Negative / Null Result ReportOpen accessNeuroscience
Sean Coulborn, Howard Bowman, R. Chris Miall et al. · 2020 · Frontiers in Human Neuroscience
Mind-wandering is associated with switching our attention to internally directed thoughts and is by definition an intrinsic, self-generated cognitive function. Interestingly, previous research showed that it may be possible to modulate its propensity externally, with transcranial direct current stimulation (tDCS) targeting different regions in the default mode and executive control networks. However, these studies used highly heterogeneous montages (targeting the dorsolateral prefrontal cortex (DLPFC), the right inferior parietal lobule (IPL), or both concurrently), often showed contradicting
View details →Negative / Null Result ReportOpen accessComputer Science
Christian Bock, Thomas Gumbsch, Michael Moor et al. · 2018 · Bioinformatics
Motivation: Most modern intensive care units record the physiological and vital signs of patients. These data can be used to extract signatures, commonly known as biomarkers, that help physicians understand the biological complexity of…
View details →Negative / Null Result ReportOpen accessMedicine
Wan-Ling Luo, Qing-Bo Wang, Yu-Kai Li et al. · 2025 · Journal of Hepatocellular Carcinoma
Purpose: This study aimed to evaluate the impact of middle hepatic vein (MHV) resection during hemihepatectomy on short-term surgical outcomes and long-term prognosis in patients with hepatocellular carcinoma (HCC). Patients and Methods:…
View details →Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Gillian D. Pullinger, Marc Guimerà Busquets, Kyriaki Nomikou et al. · 2016 · PLoS ONE
Bluetongue virus (BTV) can infect most ruminant species and is usually transmitted by adult, vector-competent biting midges (Culicoides spp.). Infection with BTV can cause severe clinical signs and can be fatal, particularly in naïve sheep and some deer species. Although 24 distinct BTV serotypes were recognized for several decades, additional 'types' have recently been identified, including BTV-25 (from Switzerland), BTV-26 (from Kuwait) and BTV-27 from France (Corsica). Although BTV-25 has failed to grow in either insect or mammalian cell cultures, BTV-26 (isolate KUW2010/02), which can be t
View details →Negative / Null Result ReportOpen accessMedicine
Majid Afshar, Mary Ryan, Felice Resnik et al. · 2025 · NEJM AI
BACKGROUND: Electronic health record (EHR) documentation is a major contributor to work-related practitioner exhaustion and the interpersonal disengagement known as burnout. Generative artificial intelligence (AI) scribes that passively…
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Thomas Farmer, Gary Brook, John McSorley et al. · 2013 · International Journal of STD & AIDS
‘Did not attend’ and cancellation rates were compared for two 12-month periods before (2009) and after (2012/2013) the introduction of routine short message service text reminders being sent to patients who have pre-booked appointments.…
View details →Negative / Null Result ReportOpen accessSocial Sciences
Giovanni Luca Cascio Rizzo, Francisco Villarroel Ordenes, Jonah Berger · 2026 · Journal of the Academy of Marketing Science
Abstract Amid the influencer marketing boom, companies are increasingly shifting resources from real to virtual (computer-generated) influencers. While virtual influencers can influence consumers, what makes their content more (or less) impactful? The current research examines whether social tie presence (i.e., appearing in photos with humans with whom they seem to have social interactions) shapes consumer engagement. A multimethod investigation, combining automated image and text analysis of thousands of social media posts with controlled experiments, demonstrates that social tie presence inc
View details →Negative / Null Result ReportOpen accessNeuroscience
Jonathan Daume, Jan Kamiński, Yousef Salimpour et al. · 2024 · Neuron
Working Memory (WM) and Long-Term Memory (LTM) are often viewed as separate cognitive systems. Little is known about how these systems interact when forming memories. We recorded single neurons in the human medial temporal lobe while…
View details →Negative / Null Result ReportOpen accessNursing
Ivana Djuričić, Philip C. Calder · 2025 · Current Atherosclerosis Reports
PURPOSE OF REVIEW: We synthesize the latest evidence (published 2020 to 2025) on the role of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in cardiovascular health, emphasizing biological mechanisms and key findings from observational studies and clinical trials related to cardiovascular disease (CVD) risk and outcomes. RECENT FINDINGS: EPA and DHA modulate lipid metabolism, inflammation, platelet and endothelial function, the gut-heart axis, ion channels and autonomic function via vagal tone, supporting cardiovascular health. While individual RCTs have produced variable results,
View details →Negative / Null Result ReportOpen accessMedicine
Hüseyin Alperen Yıldız, Emrullah Söğütdelen · 2025 · Journal of Medical Systems
BACKGROUND: Artificial intelligence (AI) chatbots are increasingly used for medical inquiries, including sensitive topics like sexually transmitted diseases (STDs). However, concerns remain regarding the reliability and readability of the information they provide. This study aimed to assess the reliability and readability of AI chatbots in providing information on STDs. The key objectives were to determine (1) the reliability of STD-related information provided by AI chatbots, and (2) whether the readability of this information meets the recommended standarts for patient education materials. M
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Araiz Hussain · 2025 · Cardiovascular Diabetology – Endocrinology Reports
Chronic hyperglycemia is the defining feature of type 2 diabetes mellitus (T2DM) and a central driver of its long-term complications, including microvascular and macrovascular diseases. Among these, cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in individuals with T2DM. Persistent glucose elevation activates multiple interrelated biochemical pathways, including the polyol pathway, formation of advanced glycation end-products, protein kinase C activation, oxidative stress via several cellular mechanisms, as well as the hexosamine biosynthetic pathway. These p
View details →Negative / Null Result ReportOpen accessMedicine
Carmen Fiuza‐Luces, Nuria Garatachea, Nathan A. Berger et al. · 2026 · PubMed
Advances in this century regarding allogeneic hematopoietic stem cell transplantation (allo-HSCT) have led to an expanding population of long-term survivors, many of whom suffer severe side effects, particularly those related to graft-versushost disease (GVHD), a potentially multi-systemic disorder caused by immunoeffector donor lymphocytes that destroy host tissues. The GVHD, especially in its chronic form (cGVHD), generates considerable morbidity and compromises the physical capacity of patients. We have reviewed the main pathophysiological aspects of the disease as well as the data availabl
View details →Negative / Null Result ReportOpen accessMathematics
Fırat Soylu, David Raymond, Arianna Gutierrez et al. · 2018 · Journal of Numerical Cognition
The impact of fingers on numerical cognition has received a great deal of attention recently. One sub-set of these studies focus on the relation between finger gnosis (also called finger sense or finger gnosia), the ability to identify and individuate fingers, and mathematical development. Studies in this subdomain have reported mixed findings so far. While some studies reported that finger gnosis correlates with or predicts mathematics abilities in younger children, others failed to replicate these results. The current study explores the relationship between finger gnosis and two arithmetic o
View details →Negative / Null Result ReportOpen accessMedicine
Chiara Corti, Beyza Koca, Tasnim Rahman et al. · 2025 · ImmunoTargets and Therapy
While immunotherapy has transformed treatment across various cancers, its impact on breast cancer is relatively limited. Recent advances have established immunotherapy as an effective approach for triple-negative breast cancer (TNBC), an…
View details →Negative / Null Result ReportOpen accessMedicine
Nouf Abdullah Alharbi · 2026 · Frontiers in Nutrition
Polyphenols, plant-derived bioactive compounds, are known for their antioxidant, anti-inflammatory, and antimicrobial properties, benefiting plant-based foods. Fermentation, driven by microbial enzymes like glycosidases, esterases, and decarboxylases, alters the chemical structure of polyphenols, enhancing their bioavailability and bioactivity. This review explores the transformation of polyphenols, particularly flavonoids and phenolic acids, during fermentation, resulting in bioactive metabolites with increased solubility, stability, and antioxidant activity, improving gastrointestinal absorp
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Carmella Evans‐Molina, Richard A. Oram · 2025 · Diabetes Obesity and Metabolism
Type 1 diabetes (T1D) has been historically regarded as a childhood-onset disease; however, recent epidemiological data indicate that adult-onset T1D accounts for a substantial proportion of cases worldwide. There is evidence that…
View details →Negative / Null Result ReportOpen accessMedicine
Bruce Cree, Joseph R. Berger, Benjamin Greenberg · 2025 · CNS Drugs
B-cell depletion with CD20-targeted agents is commonly used for treatment of multiple sclerosis (MS), other autoimmune diseases, and certain hematologic malignancies. Initial apparent success with rituximab in MS and neuromyelitis optica…
View details →Negative / Null Result ReportOpen accessEngineering
Poundoss Chellamuthu, Kirubaveni Savarimuthu, M. Gulam Nabi Alsath et al. · 2026 · Scientific Reports
Chronic Obstructive Pulmonary Disease (COPD) is a progressively debilitating and life-threatening respiratory condition that has long been attributed to exposure to airborne toxic substances like carbon monoxide (CO), a reliable biomarker…
View details →Negative / Null Result ReportOpen accessMedicine
Michelle Curran, John P. Campbell, Mark T. Drayson et al. · 2026 · PubMed
Type 1 diabetes (T1D) is a T cell mediated autoimmune disease that targets and destroys insulin-secreting pancreatic beta cells. Beta cell specific T cells are highly differentiated and show evidence of previous antigen exposure.…
View details →Negative / Null Result ReportOpen accessComputer Science
Bismark Nyaaba Akanzire, Matthew Nyaaba, Macharious Nabang · 2025 · Journal of Digital Educational Technology
This rapid study explores teacher educators’ perceptions of generative artificial intelligence (GenAI) in teacher education, conducted through a descriptive survey involving 55 teacher educators from two colleges of education in Ghana. A convenience sampling technique was adopted for data collection, and a data analysis using <i>exploratory factor analysis</i> was used to identify primary factors shaping perceptions and preparedness of GenAI integration. Key findings reveal a generally positive perception among the teacher educators, who recognize GenAI’s potential to support acade
View details →Negative / Null Result ReportOpen accessMedicine
Noriyuki Otsuki, Yuichiro Nakatsu, Toru Kubota et al. · 2013 · PLoS ONE
Canine distemper virus (CDV) becomes able to use human receptors through a single amino acid substitution in the H protein. In addition, CDV strains possessing an intact C protein replicate well in human epithelial H358 cells. The present study showed that CDV strain 007Lm, which was isolated from lymph node tissue of a dog with distemper, failed to replicate in H358 cells, although it possessed an intact C protein. Sequence analyses suggested that a cysteine-to-tyrosine substitution at position 267 of the V protein caused this growth defect. Analyses using H358 cells constitutively expressing
View details →Negative / Null Result ReportOpen accessMedicine
Deven K. Gupta, Beth H. Shaz · 2025 · Journal of Translational Medicine
BACKGROUND: Chimeric antigen receptor T-cell (CAR T-cell) therapies have shown significant promise in treating cancers and other diseases. However, the manufacturing processes for CAR T-cell therapies exhibit considerable variability,…
View details →Negative / Null Result ReportOpen accessMedicine
Michelle N. Vu, R. Elias Alvarado, Dorothea R. Morris et al. · 2026 · Nature Communications
Abstract SARS-CoV-2 Omicron variants emerged in 2022 with >30 novel amino acid mutations in the spike protein alone. While most studies focus on receptor binding domain changes, mutations in the C-terminus of S1 (CTS1), adjacent to the…
View details →Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Laurent Cavenaile, Murat Alp Celik, Xu Tian · 2026 · The Review of Economic Studies
Abstract To study competition, innovation, and industry dynamics that arise as a result of their interaction, we develop a new oligopolistic general-equilibrium Schumpeterian growth model. This model ties together the endogenous growth,…
View details →Negative / Null Result ReportOpen accessMedicine
Le Zhang, Tianyu Liu, Chuan H. He et al. · 2026 · Journal of Alzheimer s Disease
Abstract Alzheimer’s disease, the most common age-related neurodegenerative disease, is closely associated with both amyloid-ß plaque and neuroinflammation. Two thirds of Alzheimer’s disease patients are females and they have a higher…
View details →Negative / Null Result ReportOpen accessHealth Professions
Osea Giuntella, Johannes König, Luca Stella · 2025 · Scientific Reports
This study explores the relationship between artificial intelligence (AI) and workers' well-being and health using longitudinal survey data from Germany (2000-2020). Using a measure of occupational exposure to AI, we explore an event study…
View details →Negative / Null Result ReportMedicine
Hayato Omori, Yutaka Tanizawa, Rie Makuuchi et al. · 2018 · World Journal of Surgery
BACKGROUND: The REGATTA trial showed that gastrectomy followed by chemotherapy for advanced gastric cancer with a single non-curable factor did not improve survival outcomes in comparison with chemotherapy alone. Chemotherapy is therefore…
View details →Negative / Null Result ReportOpen accessMedicine
P. Gamborg Nielsen, S Madsen, L. Strömberg · 2026 · Acta Dermato Venereologica
The effects of a hydrocolloid dressing (Comfeel Ulcus) on the physical environment of chronic leg ulcers in 58 consecutive out-patients were investigated. Patients were subdivided into two groups of which Group 1 included 31 (53.4%) and…
View details →Negative / Null Result ReportOpen accessMedicine
Minghua Wu, Shervin Assassi, Gloria A. Salazar et al. · 2016 · Arthritis Research & Therapy
BACKGROUND: Systemic sclerosis (SSc)-related interstitial lung disease (ILD) has phenotypic similarities to lung involvement in idiopathic interstitial pneumonia (IIP). We aimed to assess whether genetic susceptibility loci recently identified in the large IIP genome-wide association studies (GWASs) were also risk loci for SSc overall or severity of ILD in SSc. METHODS: A total of 2571 SSc patients and 4500 healthy controls were investigated from the US discovery GWAS and additional US replication cohorts. Thirteen IIP-related selected single nucleotide polymorphisms (SNPs) were genotyped and
View details →Negative / Null Result ReportPsychology
Samantha J. Heintzelman, Jason Trent, Laura A. King · 2014 · The Journal of Positive Psychology
Growing popular interest in positive psychology may have important implications for the measurement of well-being. Five studies tested the prediction that well-being ratings are influenced by desirability bias. In Study 1, participants (N…
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