Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Ha-yeong Baek, Seung-yoon Han, Il-kyu Ahn et al. · 2026 · Physical Therapy Korea
Background: Hip abductor muscles play a critical role in stabilizing the pelvis during functional activities. A decline in hip abductor strength is associated with impaired balance and an increased risk of falls, particularly in elderly females who experience physiological changes and age-related muscle loss. Although limb dominance has been proposed to influence lower extremity muscle strength in young adults, no studies have yet examined differences in hip abductor strength between the dominant and non-dominant limbs in elderly females. Furthermore, the relationship between hip abductor stre
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Jiagen Wen, Meizi Zeng, Zhaoqian Liu et al. · 2019 · Journal of Pharmacological Sciences
Metformin is the most widely used drug among type 2 diabetes mellitus patients. However, drug interaction on metformin will influence its glucose-lowering effect or increase its side effect of lactic acidosis. In this study, a randomized, two-stage, crossover study was conducted to unveil the potential drug interaction between metformin and the anti-hypertension drug, telmisartan. Totally, 16 healthy Chinese male volunteers were enrolled. Blood samples from various time-points after drug adminstration were analyzed for metformin quantification. Oral glucose tolerance test (OGTT) was conducted
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Shaheen Akhtar, Sanjeev Verma, Navinder Pal Singh et al. · 2023 · National Journal of Physiology, Pharmacy and Pharmacology
Background: With improvement in living conditions in the population and the availability of treatments for various communicable and non-communicable diseases, the life expectancy and consequently the elderly population have increased. Stress leads to mental and physical problems. Aim and Objective: The aim of this study was to assess the effect of stress on muscle functions in the elderly. Materials and Methods: One hundred apparently healthy persons (50 males and 50 females) took part in the study. Perceived stress scale was used to measure their level of stress. Maximum voluntary contraction
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Cristiana Mateus, Cláudio J. Maia, Fernanda Domingues et al. · 2023 · Antibiotics
Aliarcobacter butzleri is a Gram-negative bacterium associated with infections of the gastrointestinal tract and widely distributed in various environments. For successful infection, A. butzleri should be able to tolerate various stresses during gastrointestinal passage, such as bile. Bile represents an antimicrobial host barrier that acts against external noxious agents and consists of a variety of bile salts. The intestinal bile salts act as detergents involved in the antimicrobial host defense; although, on the bacterial side, they could also serve as a signal to activate virulence mechanis
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