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Browse the failure-mode index

11,310 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Associations of 2000 m Rowing Ergometer Performance With Load-Velocity Relationship Variables Obtained During Bilateral and Unilateral Prone Bench Pull and Leg Press.

Pérez-Castilla A, Quidel-Catrilelbún MEL, Baena-Raya A et al. · 2026 · Journal of strength and conditioning research

Abstract Pérez-Castilla, A, Quidel-Catrilelbún, MEL, Baena-Raya, A, Miras-Moreno, S, Conceição, F, Fernandes, JFT, and Ramirez-Campillo, R. Associations of 2000 m rowing ergometer performance with load-velocity relationship variables…

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Negative / Null Result ReportMedicine

The Elevated Eosinophil Counts and Neutrophils/Lymphocytes Ratio as Predicting Biomarkers in Non-responders, Chronic Spontaneous Urticarial Patients to Cetirizine/Famotidine Treatment.

Khalili A, Estakhri Z, Shams A et al. · 2026 · Iranian journal of allergy, asthma, and immunology

The responses of patients with chronic spontaneous urticaria (CSU) to regular therapeutic options vary. While these methods are effective for some patients, many do not respond successfully. Despite several studies conducted to identify…

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Negative / Null Result ReportOpen accessMedicine

The relationship between compassion fatigue and perceptions of spirituality and spiritual care in intensive care unit nurses: a cross-sectional study.

Neşe A, Yiğit B, Bakır E · 2026 · BMC nursing

BACKGROUND: Intensive care units (ICUs) are high-stress environments that significantly predispose nurses to compassion fatigue, affecting both their well-being and the quality of patient care. Spirituality and spiritual care are often…

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Negative / Null Result ReportOpen accessMedicine

Relationship of vitamin D receptor expression with hormone receptors and other clinicopathological features in primary breast carcinomas: A retrospective cross-sectional study.

Ünlü Y, Ömeroğlu E, Ay AS et al. · 2025 · Medicine

Breast cancer is a heterogeneous disease in which estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki-67 play crucial roles in molecular subtyping, diagnosis, treatment, and…

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Negative / Null Result ReportMedicine

Incidence of thromboembolic events in testicular cancer patients receiving cisplatin (TESTCIS study).

Dubois M, Joly M, Dionne A et al. · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

IntroductionDespite the increased incidence of testicular cancer in men aged 15 to 35, patients with this neoplasm have a high five-year survival rate thanks to chemotherapy. However, cisplatin, a drug used in the standard treatment for…

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Negative / Null Result ReportMedicine

The relationship between individual characteristics and musculoskeletal disorders in tuna fishermen in Pelita Jaya Hamlet, West Seram Regency, in 2024.

Mailuhu JT, Silalahi PY, Maruanaya S et al. · 2025 · International maritime health

Background Indonesia is a country with vast marine areas. It is also part of the world's coral reef triangle, which means that Indonesia has various types of coral reef species. This gives Indonesia a very strong maritime potential.…

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Negative / Null Result ReportMedicine

A microplastic meal: A baseline assessment of microplastic polymer presence within manta-ray (Mobula alfredi) feeding grounds at D'Arros Island and the St. Joseph Atoll.

Choppy MT, Duncan MI, Gordon N et al. · 2026 · Marine pollution bulletin

Microplastic ingestion by reef manta rays (Mobula alfredi) is a threat to their health and population stability. Seychelles' outer islands are vital habitats for M. alfredi but nothing is known about marine microplastic pollution in the…

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Negative / Null Result ReportMedicine

The effect of physiological changes in estradiol hormone during the follicular phase of the menstrual cycle in healthy women on retinal ganglion cell function, retinal and optic nerve vascularization and structure.

Hamurcu M, Gültekin BP, Göçmen M et al. · 2026 · Documenta ophthalmologica. Advances in ophthalmology

Purpose This study aimed to investigate the effects of estradiol changes occurring during the early follicular phase of the menstrual cycle on retinal ganglion cell function, retinal and optic nerve vascularity and structure in healthy…

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Negative / Null Result ReportMedicine

No Association Between Anatomic Factors and Non-Contact ACL Injury Risk in 217 Female Team Sport Players: A Prospective 4.5-Year Study.

Leppänen M, Jarske H, Krosshaug T et al. · 2026 · Scandinavian journal of medicine & science in sports

The purpose of this explorative study was to investigate the association between anatomic factors and risk for non-contact anterior cruciate ligament (ACL) injuries among female team sport players. A total of 225 players from basketball,…

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Negative / Null Result ReportMedicine

Visual Outcomes and the Impact of Intermediate Segment Orientation on the Performance of an Asymmetric Multifocal Intraocular Lens.

McLintock C, Uprety S, McKelvie J et al. · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)

Purpose To evaluate the visual outcomes and the impact of intermediate segment orientation on the performance of an asymmetric multifocal intraocular lens (IOL) in patients who have cataract. Methods In this retrospective single-center…

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Negative / Null Result ReportMedicine

Understanding AI adoption in medical education: Insights from students and faculty members in Indonesian medical schools.

Rujito L, Muhaimin A, Pergodi MA et al. · 2026 · Journal of education and health promotion

Background Artificial Intelligence (AI) implementation in medical education has changed the learning process, with new forms of diagnosis, treatment planning, and patient care. Biases in AI adoption among Indonesian medical schools'…

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Negative / Null Result ReportMedicine

Connectedness to Nature, Ceremonial Participation, and Mental and Physical Health Among Rural and Urban Wixárika in Jalisco, Mexico.

Shattuck EC, McKinnon L, Herrera IR et al. · 2026 · American journal of human biology : the official journal of the Human Biology Council

Objectives Research in Western samples has repeatedly demonstrated a link between exposure to nature and natural stimuli and improved health. We sought to test these relationships in a sample of Indigenous Wixárika, whose traditional…

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Negative / Null Result ReportMedicine

Prognostic factors and outcome measures after BRAF-directed targeted therapy of unresectable metastatic BRAF<sup>V600E</sup> colorectal cancer: a study cohort-level analysis.

Colloca GA, Venturino A · 2026 · Investigational new drugs

BRAF V600E mutation in metastatic colorectal cancer (mCRC) is associated with a poor prognosis. BRAF V600E inhibitors (BRAFi) plus EGFR inhibitors + / - MEK inhibitors regimens prolonged overall survival (OS), but prognosis remains…

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Negative / Null Result ReportMedicine

The association of non-alcoholic fatty liver index, plasma metal levels, and genetic susceptibility using genome-wide type analysis.

Yu SH, Luo KH, Yang CC et al. · 2026 · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Background & aims This study aimed to explore the relationship between heavy metal exposure and the occurrence of non-alcoholic fatty liver disease (NAFLD), an area with conflicting existing research and unexplored genetic implications.…

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Negative / Null Result ReportMedicine

Serial homicide offenders and the lunar cycle.

Salafranca Barreda D, González JA · 2026 · Chronobiology international

The purpose of this research is to establish whether there are factors that contribute to the predatory activation of serial homicide offenders (SHOs) in relation to the lunar cycles. In order to move the discussion away from the media…

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Negative / Null Result ReportOpen accessMedicine

Exploring the role of ankle torque fluctuations and intramuscular coherence in gait function among older adults.

Yaguchi-Horiuchi A, Tsuji T, Takeuchi H et al. · 2025 · Aging clinical and experimental research

Objective This study aimed to investigate the relationship between ankle joint function and walking performance in older adults by assessing qualitative ankle functions through torque fluctuation analysis and tibialis anterior (TA)…

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Negative / Null Result ReportMedicine

The Impact of Operative Timing on Postoperative Complications in Laparoscopic Appendectomy for Uncomplicated Acute Appendicitis: A Retrospective Cohort Study.

Bozkurt H, Taşkın M, Özcan C et al. · 2026 · Journal of laparoendoscopic & advanced surgical techniques. Part A

Background Acute appendicitis (AA) is one of the most common surgical conditions presenting as acute abdomen. Delaying appendectomy can increase the risk of perforation. However, patients admitted or treated at night have been found to…

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Negative / Null Result ReportMedicine

Composite dietary antioxidant index and cardiovascular diseases and all-cause mortality in Iranian adults: a prospective cohort study.

Farhadnejad H, Mokhtari E, Dianati Z et al. · 2026 · Nutrition, metabolism, and cardiovascular diseases : NMCD

Background and aims Antioxidants are known to combat oxidative stress, a key factor in the development of cardiovascular diseases(CVDs) and mortality. In the current study, we aimed to prospectively investigate the relationship between the…

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Negative / Null Result ReportOpen accessMedicine

Is Demographic Concordance Between Lifestyle Coach and Participant Associated With Participant Retention and Weight Change in the National Diabetes Prevention Program Lifestyle Change Intervention?

Smart BP, Forte A, Jacobs J et al. · 2026 · Journal of diabetes research

Objective The goal of this study is to explore the association between racial/ethnic, sex, and age category concordance and participant retention and weight loss among participants enrolled in the National Diabetes Prevention Program…

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Negative / Null Result ReportMedicine

The Relationship Between Neurofilament Light Chain and B Lymphocyte Chemoattractant and Cognition in Multiple Sclerosis.

Bakırcıoglu-Duman E, Petek-Balcı FB, Calıskan-Dolu N et al. · 2026 · Noro psikiyatri arsivi

Introduction Multiple sclerosis (MS) is a chronic inflammatory, autoimmune, demyelinating disease of the central nervous system that is often associated with cognitive impairment. This study aims to investigate whether Neurofilament light…

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