11,412 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ganidagli S, Akbas ES, Ozturk ZA · 2026 · Endocrine
Purpose Sodium-glucose cotransporter-2 inhibitors are widely used in older adults with type 2 diabetes mellitus; however, their effects on geriatric syndromes remain incompletely understood. This study evaluated the longitudinal effects of…
View details →Subramaniam NK, Gagnon N, Guilbert C et al. · 2026 · Toxicological sciences : an official journal of the Society of Toxicology
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health burden and major contributor to chronic liver disease. Evidence suggests arsenic (As) and/or cadmium (Cd) exposure may influence MASLD development,…
View details →Wen Z, Claeys K, García JG et al. · 2026 · Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology
The purpose of this study was to assess reliability of performance, knee functionality and movement quality parameters in agility T-test using markerless motion capture. Seventeen healthy participants performed two sessions of agility…
View details →Ahmad I, Murillo G, Horn TL et al. · 2026 · Regulatory toxicology and pharmacology : RTP
Long-chain omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are essential omega-3 fatty acids that play crucial roles in human and animal health. EPA and DHA, are mainly sourced from marine…
View details →Chrut A, Okła S, Koziel D et al. · 2026 · Otolaryngologia polska = The Polish otolaryngology
Introduction A patient's voice, after a thyroidectomy uncomplicated by recurrent laryngeal nerve damage, may undergo both objective and subjective changes. The intensity and duration of these changes are unclear. The aim of this study was…
View details →Zwaan W, Popeijus HE, Baars JJP et al. · 2026 · Nutrients
Background/Objectives : This study evaluated the immunomodulatory effects of multiple A. bisporus strains, applying both in vitro and in vivo murine models and aiming to identify specific strains with immune modulatory properties. Methods…
View details →Kim S, Chun BC · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives To characterize pathogen-specific patterns of foodborne diseases across the full COVID-19 pandemic period, including post-non-pharmaceutical intervention (NPI) relaxation through 2024. Methods We conducted interrupted time…
View details →Ferrández-Gómez JE, Baño-Alcaraz A, Gacto-Sanchez M · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses
Purpose Myogenic temporomandibular disorder frequently co-occurs with fibromyalgia and is associated with pain, disability, and maladaptive pain cognitions. This study evaluated the short- and long-term effects of an online Pain…
View details →Malatiali S, Khamisi S, Kilarkaje N · 2026 · Acta diabetologica
Aim This study investigated the effects of angiotensin (1-7) on diabetes-induced renal injury and renal miRNA levels in obese type 2 diabetic db/db mice. Methods Treatment with angiotensin (1-7) (500 μg/kg; i.p.) was started when the mice…
View details →Mahmoud WS, Alhowimel A, Almotery A et al. · 2026 · Scientific reports
Non-specific low back pain (NSLBP) represents about 80-95% of all LBP cases, yet the optimal lumbar traction position for effective treatment remains debated. To investigate the effect of different positions during lumbar traction on pain,…
View details →Liu S, Yu J, Cheng X et al. · 2026 · Eye (London, England)
Background Multifocal intraocular lenses (MF-IOLs) have been developed to enhance far, intermediate, and near vision postoperatively of cataract surgery patients. This study investigates the improvement of visual function in cataract…
View details →Cabizosu A, Zoffoli A, Mevi R et al. · 2026 · Physiological measurement
Objective. Infrared thermography is projected as an innovative and very promising tool for the observation of muscle response to fatigue. The aim of this study was to observe the skin temperature (Tsk) by thermography about acute muscle…
View details →Wysokinski A, Wiśniewska-Kadżajan B, Łozak I · 2026 · BMC plant biology
Background Sulphur is an important macronutrient for legume plants because it influences the formation and functioning of root nodules, the activity of enzymes reducing molecular nitrogen to available forms for plants, the formation of…
View details →Naka K, Ojha SK, Dimov LD · 2026 · Forest Ecology and Management.
This study examines the structural and compositional changes in Table Mountain pine (Pinus pungens Lamb.) associated forest ecosystems over a two-decade period (1997–2017) and assesses the species’ status across disturbed and undisturbed…
View details →Tepe D, Deligozoglu D, Baskan C et al. · 2026 · Journal of pediatric endocrinology & metabolism : JPEM
Objectives Although Graves' orbitopathy (GO) in childhood is generally considered milder than in adults, data regarding its clinical course and relationship with thyroid autoimmunity remain limited. This study aimed to evaluate the…
View details →White DE, Ghani U, Pedersen M et al. · 2025 · Journal of neuroengineering and rehabilitation
Background Unilateral nostril breathing (UNB) has a history linked to ancient yogic traditions where it is believed to affect both physical and mental states however the mechanism(s) by which this technique potentially influences brain…
View details →Scalvini S, Donati V, Zanelli E et al. · 2026 · European journal of internal medicine
Background Heart failure (HF) and type 2 diabetes (T2DM) are significant public health concerns. This study evaluated a 6-month home-based telemedicine program for older patients with combined HF and T2DM. The primary outcome was exercise…
View details →Guillen B, Zambrano-Huailla R, Chirinos JA · 2026 · Revista de gastroenterologia de Mexico (English)
Introduction The use of artificial intelligence (AI) in endoscopic studies has grown in recent years. The present study evaluates the performance of AI in detecting polyps and adenomas in daily clinical practice. Materials and methods A…
View details →Hollenbach J, Schroth FN, Hildebrand C et al. · 2026 · Placenta
Introduction Osteopontin (OPN) is an extracellular matrix protein secreted by endometrial glands during early pregnancy and is required for adhesion and signal transduction at the uterine-placental surface. In sheep, endometrial OPN…
View details →Sas A, Jónyer D, Valikovics A et al. · 2026 · Journal of clinical medicine
Background/Objectives: Rheumatoid arthritis (RA) has been associated with accelerated atherosclerosis and cerebrovascular alterations. Our 2017 study compared 60 RA patients to healthy controls, assessing vascular, neurological, and…
View details →Sangiorgi G, Cavinato L, Cristoferi M et al. · 2026 · Respiratory medicine
Background Elexacaftor/tezacaftor/ivacaftor (ETI) therapy rapidly improves monocyte antimicrobial activity in people with cystic fibrosis (pwCF). Here, we investigated the effect of long-term ETI therapy on Pseudomonas aeruginosa…
View details →Gökcek Taraç M, Çolak M · 2026 · American journal of dentistry
Purpose To evaluate the effects of two commonly used pediatric medical syrups on the surface roughness and the adhesion of Streptococcus mutans (S. mutans) to three fluoride-releasing restorative materials: high-viscosity glass-ionomer,…
View details →Houska N, McCaw N, Meneses EC et al. · 2026 · Journal of cardiothoracic and vascular anesthesia
Objectives To describe thrombotic outcomes associated with Factor Eight Inhibitor Bypassing Activity (FEIBA) exposure in neonates and infants undergoing cardiac surgery with cardiopulmonary bypass (CPB), including the Norwood procedure.…
View details →Almuashi H, AbuMostafa A · 2026 · Quintessence international (Berlin, Germany : 1985)
Objective The management of pain in dental procedures is crucial, as local anesthetic injections may induce patient anxiety and discomfort. Various techniques including Vibraject and Dentapen have been devised to alleviate injection…
View details →Veli-Quispe D, Urquizo-Prado S, Cesare-Ariza E et al. · 2026 · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Background Cerebrovascular disease remains a leading cause of mortality worldwide. In Peru, evidence on recent mortality trends and regional disparities is limited. Objective To evaluate temporal trends and regional disparities in…
View details →Qin LG, Camarda ND, Kasetty VM et al. · 2026 · Journal of vitreoretinal diseases
Purpose: To investigate the effect of intravitreal (IVT) aflibercept injection monotherapy on retinal ischemia in eyes with severe proliferative diabetic retinopathy (PDR) that underwent pars plana vitrectomy (PPV) without panretinal…
View details →Li DY, Kim S, Javed S et al. · 2026 · Regional anesthesia and pain medicine
Background Methadone is commonly used as an alternative to other opioids for managing cancer-related pain. High-dose methadone, primarily in opioid dependence treatment, has been associated with QTc prolongation and dangerous arrhythmias.…
View details →Švajger U, Kolar M, Pompe B et al. · 2026 · Cartilage
ObjectiveUmbilical cord-derived mesenchymal stromal cells (UC-MSCs) are a promising treatment for knee osteoarthritis (KOA). This study aimed to (1) characterize early synovial fluid biomarker changes after intra-articular UC-MSCs therapy…
View details →Ramachandran I, Rajesh AT, Elumalai P · 2026 · Fish physiology and biochemistry
The current study aimed to ascertain the growth, antioxidant capacity, intestinal architecture, digestive enzyme activity, and disease resistance of S. agalactiae of Nile tilapia (Oreochromis niloticus) fed a diet enriched with…
View details →Kaba Ö, Tanatar A, Koç R et al. · 2026 · Jornal de pediatria
Objectives Colchicine is an essential component of familial Mediterranean fever (FMF) treatment. It is suggested that it may affect vitamin B 12 levels by affecting intestinal absorption. This research focused on examining the impact of…
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