11,412 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Berry A, Watson M, Moore M et al. · 2026 · Epilepsy & behavior : E&B
Background and objectives Functional/dissociative seizures (FDS) are frequently treated with one-to-one therapeutic interventions. However, data describing patient-reported outcome measures (PROMs) following group-based therapy remain…
View details →Barberán-Bernardos L, Ariza-Gracia MA, Büchler P et al. · 2026 · Life (Basel, Switzerland)
This study aims to characterize diurnal changes in corneal geometry of the anterior and posterior cornea in healthy eyes using global and sector-based metrics, and to explore their associations with lifestyle-related factors. A prospective…
View details →Cheng CW, Fang WF, Yang YM et al. · 2026 · Immunopharmacology and immunotoxicology
Background Hydroxychloroquine (HCQ) is a commonly used immunomodulatory drug in various autoimmune diseases; however, its role in autoimmune thyroid diseases (AITDs) remains unclear. Objective This study aimed to evaluate the potential…
View details →Volpe G, Bonanata M, Peyla A et al. · 2026 · Ophthalmology and therapy
Introduction Intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy is the standard of care for neovascular age-related macular degeneration (nAMD) and other retinal vascular diseases. However, transient post-injection…
View details →Genç E, Bilekyiğit Kurt C, Evrim Karadağ Saygi N et al. · 2026 · Journal of pediatric endocrinology & metabolism : JPEM
Objectives Musculoskeletal abnormalities are common to mucopolysaccharidoses (MPS) and can negatively affect the patient's quality of life. Data on course of musculoskeletal findings of MPS type IVA and VI are very insufficient. This study…
View details →Martikainen A, Eloranta AM, Schwab U et al. · 2026 · Trials
Background Lifestyle interventions can reduce the risk of becoming an overweight adult and reduce the risk of health problems. The aim was to investigate the effects of obesity treatment on BMI-for-age, metabolic markers, and quality of…
View details →Asbi T, Mayer Y, Sarikov R et al. · 2026 · The Saudi dental journal
Maxillectomy produces extensive oral and maxillofacial defects that disrupt normal physiology and often require obturator prostheses for functional and aesthetic rehabilitation. Although these devices are routinely used, their influence on…
View details →Stoll PD, Thol F, Spuck N et al. · 2026 · The Journal of craniofacial surgery
Introduction Orthognathic surgery is traditionally considered painful, often prompting opioid use. In the context of rising opioid-related harm, this study assessed postoperative pain levels, factors influencing analgesic requirements, and…
View details →Lafitte E, Sfumato P, Walz J et al. · 2026 · World journal of urology
Introduction Preoperative anemia (PA) and red blood cell transfusion (RBT) are associated with decreased survival in several cancers. In muscle-invasive bladder cancer (MIBC), anemia is frequent and may be worsened by neoadjuvant…
View details →Jones A, Johnco C, Beyersmann E et al. · 2026 · Child psychiatry and human development
Poor reading ability is associated with internalising symptoms in children; however, little research has been done with adolescents. The current study used self- and parent-report data from two cohorts of the Longitudinal Study of…
View details →Majidi S, Rouhi A · 2026 · BMC primary care
Background Obsessive-Compulsive Disorder (OCD) is one of the psychiatric disorders which characterized by unwanted thoughts (obsessions) and repetitive behaviors (compulsions). Mental health problems can affect job performance of…
View details →Yaemrattanakul W, Manachamni K, Ruangrattanapong J et al. · 2026 · BMC psychology
Background Healthcare undergraduate students often face high cognitive and emotional stress, negatively affecting their working memory and well-being. Mindfulness-based practices, such as sitting meditation and body scan, are proposed to…
View details →Stankovičová V, Nováček VL, Rozsíval P · 2026 · Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti
Aim The aim of this study was to assess the effect of Rexon-Eye therapy, based on quantum molecular resonance (QMR) technology, optical parameters, tear film stability, and patients' subjective symptoms. Material and methods A total of 30…
View details →Mancarella M, Novara L, Carignano S et al. · 2026 · The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
Objectives Uterine leiomyomas may cause disorders such as bleeding and bulky symptoms impacting on quality of life; a recent therapeutic option is relugolix, a GnRH antagonist effective in controlling bleeding and reducing the size of…
View details →Thomas L, Hazell G, Baczynska K et al. · 2026 · Photochemistry and photobiology
Far-UVC (200-235 nm) has emerged as a safe and effective modality to inactivate pathogens in an indoor setting. trans-urocanic acid (UCA) is a chromophore that resides in the stratum corneum of the skin and is converted into the more…
View details →McLintock C, Uprety S, McKelvie J et al. · 2026 · International ophthalmology
Background We aim to evaluate the effect of pharmacological pupil dilation on spherical and toric intraocular lens (IOL) power calculations using biometric measurements from the Anterion optical biometer. Methods This was a prospective…
View details →Reinprayoon U, Yaisawang S, Israsena N et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose Descemet Membrane Endothelial Keratoplasty (DMEK) is a surgical intervention for restoring endothelial function in Fuchs endothelial corneal dystrophy (FECD). However, changes in corneal biomechanical properties assessed using…
View details →Chen S, Kortas J, Ren Y et al. · 2026 · Healthcare (Basel, Switzerland)
Objectives : Explore and compare the effects of 8-week time-restricted eating (TRE), walking exercise, and their combination on fat and lean muscle distribution in female college students with hidden obesity. Methods : A total of 68…
View details →Aliyev F, Yigit S, Yucel E et al. · 2026 · Scientific reports
Pressure rise time (PRT) is an adjustable ventilator parameter that regulates the rate of inspiratory flow delivery and may influence ventilator mechanics and tissue oxygenation. However, its short-term physiological effects in neonates…
View details →Tavasoli H, Rajabi MM, Sadat Hoseini AS · 2026 · Journal of pediatric nursing
Purpose To determine the effect of harmonica-based breathing and airway clearance exercises on pulmonary function in children with cystic fibrosis (CF). Methods This randomized controlled trial included 70 children with CF aged 8-18 years.…
View details →Fernández-León MF, Flórez Acosta LR, Fernández-León AM · 2026 · Foods (Basel, Switzerland)
Almond ( Prunus dulcis ) is a highly nutritious nut, rich in unsaturated fatty acids, fibre, and bioactive compounds such as tocopherols, phenolic compounds, and carotenoids. Processing methods commonly applied in the almond industry,…
View details →Khalaf NF, Salman IN, Ad'hiah AH et al. · 2026 · Scientific reports
Type 2 diabetes mellitus (T2DM) is a dysfunctional metabolic disorder characterized by low-grade inflammation. Peripheral neuropathy (PN), nephropathy (NE), and retinopathy (RT) are prominent microvascular complications (MICs) associated…
View details →Masakazu H, Akiko M, Midori Y et al. · 2026 · Scientific reports
This study was conducted to evaluate the longitudinal morphological changes in cone density (CD) in patients with the eyes shut homolog (EYS)-associated retinitis pigmentosa (RP) using adaptive optics (AO) fundus imaging and to assess its…
View details →Kabukçu HO, Müftüoğulları S, Yıldız E · 2026 · Children (Basel, Switzerland)
Objectives: The diagnosis of pediatric acute appendicitis remains challenging due to clinical findings that overlap with nonspecific abdominal pain (NSAP). In this study, the value of fibrinogen in the diagnosis of pediatric acute…
View details →Ashrafi F, Moulavi P, Jamalipanah Z et al. · 2026 · AMB Express
This study evaluated the antibacterial and antibiofilm activity of Echinacea-loaded amino-functionalized UIO-66 MOF nanoparticles against clinical Pseudomonas aeruginosa isolates. Echinacea-loaded amino-functionalized UIO-66 metal-organic…
View details →Wang MK, Wang MR, Niu YD et al. · 2026 · Pest management science
Background Autophagy is essential for insect reproduction and endosymbiont homeostasis, with Atg8 serving as a key autophagy-related gene. However, the specific role of LsAtg8 in reproduction and endosymbiont regulation in Laodelphax…
View details →Fopka-Kowalczyk M, Krajnik M · 2026 · BMC medical education
Background This article presents an evaluation of the first obligatory programme on 'Spirituality in Medicine' for medical students in Poland, implemented at the Collegium Medicum in Bydgoszcz of the Nicolaus Copernicus University in…
View details →Tanabe K, Kojima S, Saito K et al. · 2026 · Scientific reports
Transcutaneous auricular vagus nerve stimulation (taVNS) is a noninvasive electrical stimulation technique applied to the left cymba concha that may improve somatosensory impairment in stroke. Although previous studies have investigated…
View details →Díaz Duque Á, Kaur S, Wolf M et al. · 2026 · Faraday discussions
Revealing the structural properties of water at charged interfaces is key for a better understanding of interfacial processes in various fields such as atmospheric chemistry, biology, and electrochemistry. One important aspect of the…
View details →Akanuma S, Sugano Y, Shimmura S et al. · 2026 · Legal medicine (Tokyo, Japan)
DNA evidence can be used to link perpetrators to crime scenes or victims. We examined all Japanese criminal court cases included in a commercially available LEX/DB Internet (LEX database) from 1989, the year DNA analysis was first used as…
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