11,407 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Dambro, Anderson, Clebak et al. · 2025 · Family medicine
The integration of artificial intelligence (AI) in medical education primarily has focused on clinical applications, with limited investigation into its role in learner assessment. This study explores AI usage among family medicine…
View details →Than V, Casal DI, Sica A · 2024 · Cureus
We present a case of a 59-year-old female who presented with progressively worsening altered mental status, seizures, and neuropsychiatric symptoms. Over the course of her emergency visit and admission to the hospital, laboratory tests…
View details →Noda, Takahara, Hayashi et al. · 2026 · Journal of orthopaedic case reports
Given the high mortality associated with femoral trochanteric fractures, reliable pre-operative estimation of post-operative death risk is essential. Commonly used scoring systems demonstrate only moderate predictive ability, largely…
View details →Zhou, Vo, Morelli et al. · 2026 · Journal of clinical pharmacology
Bemnifosbuvir is a novel oral guanosine nucleotide prodrug with potent pan-genotypic inhibitory activity against hepatitis C virus. In vitro studies assessing the inhibition or induction potential of bemnifosbuvir on the CYP450 and UGT1A1…
View details →Borrell-García, Mestanza-Tocto, Boo-Gordillo et al. · 2026 · European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
The present study aimed to assess parental knowledge of paediatric oral health among parents and guardians of children aged 2-12 years in Valencia, Spain, and to analyse its association with key sociodemographic variables. A…
View details →Heidtmann, Umbreit, Eckoldt · 2026 · Journal of pediatric urology
Legislation restricting surgical interventions in children with differences of sex development (DSD) has intensified debate about female genital restoration surgery (FGRS) in patients with congenital adrenal hyperplasia (CAH). Long-term…
View details →Paap K, Majoubi J · 2025 · Experimental psychology
In a recent article, Ellen Bialystok argued that bilingual experience enhances nonverbal cognition, that its effects are continuous rather than categorical, and that selective attention is the key mechanism underlying cognitive changes in…
View details →Mukherjee, Watson, Wallbanks et al. · 2026 · Cureus
Obesity as the primary cause of acute hypercapnic respiratory failure (AHRF) receiving acute non-invasive ventilation (NIV) has doubled within a decade. We analysed the primary diagnoses for receiving home mechanical ventilation (HMV) upon…
View details →Scanlin, Salazar · 2026 · Veterinary anaesthesia and analgesia
To compare postoperative analgesic efficacy between ropivacaine and liposomal bupivacaine when used for an erector spinae plane (ESP) block as part of analgesic management for hemilaminectomy surgery caudal to the eleventh thoracic…
View details →Gayraud, Lequy, Hucteau et al. · 2026 · Ophthalmology science
Age-related macular degeneration (AMD) and cataracts are part of the leading causes of blindness globally, with oxidative stress being a key factor in their development. Air pollution, known to exacerbate oxidative stress, may contribute…
View details →Ankmnal Veeranna, Chapman · 2026 · American journal of audiology
The purpose of the present study was to determine whether standard and high-frequency transducers influence test scores on clinically used speech-in-noise (SIN) assessments, such as the Word-In-Noise (WIN) and QuickSIN tests. Sixteen…
View details →Wu, Zhang, Wang et al. · 2026 · Frontiers in ophthalmology
To assess central corneal thickness (CCT), as well as the density and morphology of corneal endothelial cells (ECD) in myopic eyes. A total of 400 patients scheduled for myopic refractive surgery were consecutively enrolled in this study.…
View details →Sai-Ut, Indriani, Srisakultiew et al. · 2026 · Food science of animal resources
Meat tenderness is key to consumer acceptance but is challenged by goat meat's leanness and high connective tissue content. A promising solution is the in-pack combination of ultrasonication (US) and sous-vide (SV) technologies to enhance…
View details →Li, Peng, Song et al. · 2026 · Poultry science
The development and utilization of unconventional feed such as sprayed corn bran (SCB) have effectively alleviated the shortage of feed raw materials, although its application in meat geese production has rarely been reported. Therefore,…
View details →Bao, Wu, Li et al. · 2026 · BMC cardiovascular disorders
Atrial fibrillation (AF) with coronary artery disease (CAD) requiring percutaneous coronary intervention (PCI) - including both acute and chronic presentations - is common, yet the optimal antithrombotic regimen remains unclear. This study…
View details →Mukhopadhyay, Modgekar, Yang-Hood et al. · 2026 · Scientific reports
Quantal synaptic transmission in vestibular endorgans is glutamatergic. Here, we investigated the vestibular phenotype of deaf Vglut3 -/- (Slc17a8 -/- ) mice from the cellular to behavioral levels. In Vglut3 -/- mice, quantal synaptic…
View details →Miyazaki, Ishigo, Yamada et al. · 2026 · Journal of pharmaceutical health care and sciences
Candidemia has high mortality and requires early antifungal stewardship (AFS). Management by non-infectious disease specialists has been associated with worse outcomes, particularly in small- and medium-sized hospitals where infectious…
View details →Wiseman R, Watt C · 2026 · PeerJ
Preregistration is commonly seen as an effective way of reducing questionable research practices within psychology. This procedure happens prior to data collection/analysis and usually involves either sending in a research plan to a study…
View details →Hansen-Lewis J, Marcus M · 2025 · American economic journal. Economic policy
Maritime shipping emits as much fine particulate matter as half of global road traffic. We are the first to measure the consequences of US maritime emissions standards on air quality, human health, racial exposure disparities, and…
View details →Schauer JM · 2023 · Multivariate behavioral research
A prominent approach to studying the replication crisis has been to conduct replications of several different scientific findings as part of the same research effort. The reported proportion of findings that these programs determined…
View details →Orhan B, Nauta M · 2026 · Death studies
Meaning Management Theory suggests that engaging with meaning-related resources helps individuals constructively regulate consciously experienced death anxiety. Consistent with that theory, we tested whether a single-session, online…
View details →Mitsuhara, Shimizu, Ebihara et al. · 2026 · Acute medicine & surgery
This study aimed to evaluate whether early enteral nutrition can be administered without increasing gastrointestinal complications in patients receiving mechanical circulatory support. This retrospective observational study was conducted…
View details →Pang, Hageman, Lou · 2026 · International journal of pharmaceutics
Tissue back pressure is an important indicator of tissue resistance during subcutaneous injection and is associated with injection performance and patient experience. Currently, assessments of tissue back pressure during injection are…
View details →Littlejohn, Zuckerman, Gargurevich et al. · 2026 · Journal of asthma and allergy
Determine if there is a difference in race, socioeconomic factors and baseline asthma severity at the time of biologic initiation and whether those characteristics are associated with response to therapy within 18 months of initiation.…
View details →Shen, Dai, Hu et al. · 2026 · Quantitative imaging in medicine and surgery
Inguinal lymph node (ILN) metastasis significantly affects prognosis and treatment strategies in patients with gynecological malignancies. Conventional ultrasound (US) provides morphological assessment but has limited sensitivity for…
View details →Nakamura N · 2026 · Annals of the ICRP
Radiation risks for cancer are classified into probabilistic effects because the induction of oncogenic mutations in a single epithelial cell is thought to be causally related to the process of carcinogenesis. However, two observations…
View details →Joshi, Scheuer, Chew et al. · 2026 · JACC. Heart failure
Heart transplantation (HT) from donation after circulatory death (DCD) donors has successfully expanded the donor pool with excellent short-term survival outcomes, but there is uncertainty regarding long-term outcomes. This study compared…
View details →Shi, Qu, Wang et al. · 2026 · Frontiers in microbiology
Human papillomavirus 33 (HPV33) is among the five most prevalent HPV genotypes in China and is commonly involved in co-infections. However, the synergistic effects of specific genotype combinations on cervical carcinogenesis remain…
View details →Sheikhzadeh, Sheikhhoseini, Piri et al. · 2026 · PeerJ
Many yoga poses involve supporting part or all of the body weight on the shoulder girdle and arms, which impose high loadings on the shoulder girdle. The present study aims to investigate the differences in electromyographic (EMG) activity…
View details →Iwamoto, Takagawa · 2026 · Scientific reports
Accurate modelling of tropical cyclones (TCs) is essential for reliable storm surge simulations, as TCs provide the primary external forcing. While deep learning models have demonstrated effectiveness in TC modelling, a challenge remains…
View details →