11,310 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Burger C, Pirotte M, Ray K et al. · 2026 · The western journal of emergency medicine
Introduction Emergency physicians commonly receive feedback in the form of performance metrics such as patients seen per hour. Reviewing metrics has been associated with increased stress and burnout. Although effects on efficiency have…
View details →Jang YE, Kim Y, Kim HI et al. · 2026 · Journal of endodontics
Introduction Hydraulic calcium silicate cement-based sealers (CSC sealers) are now frequently used with warm vertical compaction in root canal treatment. However, the impact of heat on the biological properties of CSC sealers remains…
View details →Nakano H, Shiinoki T · 2026 · Journal of neuro-oncology
PURPOSE: The radiosensitivity index (RSI) is a transcriptomic predictor of intrinsic radiosensitivity. The longitudinal behavior of the RSI in glioma and its variation across intratumoral cellular states have been unknown. We investigated…
View details →Silva TR, Poínhos R, Oliveira BMPM et al. · 2026 · The British journal of nutrition
While rapid four-compartment (4C) models have demonstrated cross-sectional validity in diverse populations, including athletes, their longitudinal validity remains unverified. This study aims to evaluate the longitudinal validity of…
View details →Hugueny J, de Ricolfis A, Johnson N et al. · 2025 · Thrombosis research
Objective This review aimed to synthesize recent data on venous thromboembolism (VTE) risk in the context of masculinizing hormone therapy with testosterone. Methods An electronic search was performed in MEDLINE/PubMed without date…
View details →Rhodes J, Leach A · 2026 · Journal of sport & exercise psychology
Imagery is widely used in sport, but its effectiveness depends on how it is structured and the range of senses engaged. This study compared Functional Imagery Training-a multisensory, motivational intervention-with single-sense internal…
View details →Anthuparambil ND, Timmermann S, Dargasz M et al. · 2026 · The Journal of chemical physics
The effect of lowered pH on the thermal gelation behavior of hen egg yolk was investigated over the temperature range of 58-72 °C using low-dose X-ray photon correlation spectroscopy in ultra-small-angle X-ray scattering geometry.…
View details →Tikhonova P, Mekonnen Z, Belanger KD et al. · 2026 · Communications medicine
Background Mass deworming programs using anthelmintic drugs are a common public health strategy for controlling soil-transmitted helminth (STH) infections in high-risk, low-income countries. However, whether routine deworming induces…
View details →Ma CY, Chen J, Fu Y et al. · 2026 · BMC medical education
Background Competence in radiation oncology is still commonly expected to emerge through apprenticeship, although essential tasks such as target delineation, treatment-plan review, and multidisciplinary reasoning are not reliably sampled…
View details →Burnet G, Vasic I, Sauaia A et al. · 2026 · Journal of surgical education
Objective To determine the efficacy of cognitive behavioral therapy (CBT) on stress, anxiety, burnout, and depression in surgical interns and to determine the optimal timing of CBT. Our hypothesis was that CBT could improve each of these…
View details →Mehraj F, Bhat MA, Mangulkar A et al. · 2025 · Journal of pharmacy & bioallied sciences
Introduction In recent years, there has been a great deal of interest in research because of the changes that the extraction of premolars has caused to the structures surrounding of the upper airway. This is because it's thought that these…
View details →Benson JC, Carr CM, Mark IT et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Wrong-site vertebroplasty is a known complication of image-guided procedures. Although rare, these errors have considerable clinical and medicolegal implications and are considered "never" events. This iterative…
View details →Rodriguez-Belenguer P, Beser-Robles M, Marfil-Trujillo M et al. · 2026 · Computer methods and programs in biomedicine
Background and objectives Radiomics-based machine learning models are increasingly used for clinical decision-making, yet their reliability is often constrained by limited sample sizes and class imbalance in imaging datasets. While prior…
View details →Denstad SE, Volløyhaug I, Lieng M et al. · 2026 · Journal of minimally invasive gynecology
Study objective To evaluate changes in health-related quality of life (HRQoL) 3 years after laparoscopic hysterectomy (LH) for benign, prophylactic, and malignant indications, and to identify baseline factors associated with these changes.…
View details →Yuan L, Li T, Jiang D et al. · 2026 · Insect science
A broad host range facilitates the rapid spread of Hyphantria cunea. This study explored the mechanism underlying the multi-host adaptability of H. cunea larvae, focusing on glutathione S-transferase (GST), and developed nucleic acid…
View details →Tan J, Rurak BK, Helmich RC et al. · 2026 · Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Objective Tremor is a common motor symptom of Parkinson's disease (PD) that reduces quality of life. Cortico-cortical paired associative stimulation (ccPAS) is a transcranial magnetic stimulation protocol that induces connective…
View details →Bode-Akinboye E, Rietdijk R, Dale R et al. · 2026 · American journal of speech-language pathology
Purpose Adults with moderate-severe traumatic brain injury (TBI) often have significant communication challenges, particularly in interpersonal conversations. Most research aiming to understand these challenges has used static measures of…
View details →Acar GC, Tuncel S · 2026 · PeerJ
Background This study aims to investigate the effects of Zumba dance training conducted in a mirrored environment on participants' knee joint position sense (proprioception), static-dynamic balance and mood state. Methods A total of 39…
View details →Kucuk SD, Jabet P, Groso A et al. · 2026 · South African Journal of Botany.
Black rice (Oryza sativa L.) is a rich source of phenolics and flavonoids, making it a candidate ingredient for dermocosmetic applications. This study aimed to evaluate the bioactive potential of an ethanolic black rice extract as a…
View details →Dong ZH, Zhang Y, Lu J et al. · 2026 · Journal of hazardous materials
Acetaminophen (APAP) is frequently detected in municipal wastewater, yet its effect on heterotrophic denitrification remains insufficiently resolved. Here, Paracoccus denitrificans was exposed to 0.5 and 7.5 ppm APAP, representing lower…
View details →Dhurat RS, Sharma R, Shetty C et al. · 2025 · Skin appendage disorders
Introduction Prostaglandin D2 (PGD2) is elevated in the bald scalp of men with androgenetic alopecia (AGA) and inhibits hair growth. Cetirizine, an H1-antihistamine, reduces PGD2 production and has anti-inflammatory effects, making it a…
View details →Kober M, Livingston JA, Barrick C et al. · 2026 · Journal of holistic nursing : official journal of the American Holistic Nurses' Association
Background: Emergency department (ED) nurses are routinely exposed to high-stress clinical environments, increasing their risk for burnout and emotional exhaustion. In holistic nursing, self-care is viewed as a professional and ethical…
View details →Žilytė A, Petrikaitė V · 2026 · Cells
In this study, we evaluated the impact of different in vitro 3D culture modelling methods on the activity of doxorubicin (DOX) and 5-fluorouracil (5-FU) in human melanoma spheroids. Human melanoma A375 and IGR39 spheroids were generated…
View details →Jamal H, LaLoggia M, Boggarapu S et al. · 2025 · JACC. Case reports
Background The overuse of telemetry without indication leads to alarm fatigue, unnecessary costs, and reduced patient satisfaction. Unnecessary telemetry use does not improve patient outcomes. Rationale We hypothesized that a…
View details →Kayin Y, Oztas B · 2026 · Nurse education in practice
Aim This study examined the effects of PechaKucha and Teach-Back teaching techniques on nursing students' knowledge, self-efficacy and satisfaction regarding discharge education. Background Effective discharge education requires strategies…
View details →Hirsch T, Moser U, Wolf A et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Purpose This prospective pilot study aimed to evaluate whether dupilumab therapy induces measurable changes in the sinonasal microbiome of patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Methods Eight CRSwNP patients…
View details →Parakkal T, Kuriakose MJ, Natarajan PV et al. · 2026 · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie
Surgically facilitated anterior maxillary distraction (AMD) is used for the treatment of maxillary hypoplasia secondary to cleft lip and palate (CLP). In this study, the soft and hard tissue changes following AMD in growing patients with…
View details →Stanford K, Cain RM, Millis D et al. · 2026 · American journal of veterinary research
Objective To identify the effects of incline and decline treadmill trotting on forelimb muscle activity in dogs using electromyography (EMG). Methods Data were collected for a prospective within-subject, repeated-measures study in January…
View details →da Silva PCH, Faria TV, Galvani LD et al. · 2026 · The Angle orthodontist
Objectives To evaluate the effect of different antimicrobial solutions on the mechanical properties of aligners (Invisalign, Align Technology Inc., San Jose, CA, USA). Material and methods Invisalign aligners were used, originating from an…
View details →Ayazi H, Kalani N, Rabiee M et al. · 2026 · Musculoskeletal care
Background and purpose Lumbopelvic rhythm describes the relationship between the lumbar spine and hip motion during trunk bending tasks, while the lumbar lordosis angle represents the normal sagittal curvature of the lumbar spine. This…
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