11,309 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Escoffier, Hedhli, Campos-Juanatey et al. · 2026 · The French journal of urology
Artificial intelligence (AI) is increasingly used in surgery, but its role in reconstructive urology remains insufficiently studied. The aim of this work was to evaluate the theoretical knowledge of several AI platforms and compare their…
View details →Yip, Xu, Liu et al. · 2026 · Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
To build a visual question answering (VQA) dataset for fine-tuning and evaluating vision-language models (VLMs) in myopic maculopathy (MM). Cross-sectional study. Colour fundus photographs (CFPs) from two publicly available datasets were…
View details →Peng, Wang, Xiao et al. · 2026 · Journal of minimally invasive gynecology
To compare the effectiveness and safety of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) pelvic reconstruction (PRC), vNOTES presacral-uterosacral ligament suspension (PULS), and sacrospinous ligament fixation…
View details →Rocha, Dos Anjos, Pinho et al. · 2026 · Journal of dentistry
This 12-month, double-blind, parallel, randomized controlled trial compared the material fracture/retention rates of occluso-proximal direct composite resin restorations associated with polyethylene fiber (CR+PF; Ribbond®) with…
View details →Kim, Yang, Kuang et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
Conventional cephalometry relies on measurements derived from a limited set of landmarks and population-based norms, which may not fully capture individual skeletal form. Although evaluated independently, many cephalometric variables…
View details →Olson, Perera, Kamal et al. · 2026 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Quantitative pupillometry (QP) provides a reliable measure of the pupillary light reflex. The pupil accommodation reflex (P-AR) occurs when there is a change in visual focus from near to far or from far to near. The ability to measure the…
View details →Jiang, Zhu, Gan et al. · 2026 · European journal of radiology
This study aimed to investigate the effectiveness and safety of endovascular treatment (EVT) in patients with large ischemic strokes assessed by non-contrast CT (NCCT) within the extended time window. This study was a sub-analysis of a…
View details →Zhao, Wang · 2026 · Acta psychologica
Handwashing, as a common physical cleansing behavior, not only serves a physiological cleaning function but is also believed to symbolically "wash away" emotional experiences or mental residues. Previous research has primarily focused on…
View details →Karnati, Wu, Kaghazchi et al. · 2026 · Journal of neurosurgery. Spine
The aim of this study was to evaluate the impact of initial postoperative gabapentinoid prescription on chronic postoperative opioid use in patients who underwent short-segment lumbar instrumentation by using a large multicenter electronic…
View details →Chen, Maddali, Langlotz et al. · 2026 · Journal of medical Internet research
Most clinically relevant data are in unstructured clinical notes, which are verbose and imprecise, making structured data extraction a costly bottleneck for screening patients for studies or maintaining health care registries. This…
View details →Fuentes-Expósito, Frid, Muñoz-Mateu et al. · 2026 · JCO clinical cancer informatics
We evaluated whether offering access to a multicomponent mHealth app improves quality of life (QoL) and psychosocial outcomes among breast cancer survivors under pragmatic, nonprescriptive conditions. In this single-center, randomized,…
View details →Esposito, Bocari, Cho et al. · 2026 · The International journal of oral & maxillofacial implants
This multicenter randomized controlled trial compared the clinical effectiveness of 7.0-mm wide-diameter implants with 5.0-mm conventional-diameter implants placed immediately after molar extraction. Thirty-nine patients needing a single…
View details →Li, Ma, Liu et al. · 2026 · Tropical animal health and production
In this study, we used lactic acid bacteria to ferment the byproduct of Arundo donax papermaking, Arundo donax juice (ADJ), to obtain fermented Arundo donax juice (FADJ). We aimed to investigate the effects of FADJ on the growth…
View details →Zang, Yan, Dong et al. · 2026 · The Journal of craniofacial surgery
Scar is an inevitable pathological product of tissue injury repair, and pathological scars often occur in exposed areas, bringing severe psychological burden and economic losses to patients. With the popularization of digital healthcare,…
View details →Li, Sugita, Togawa et al. · 2026 · Frontiers in plant science
High planting densities in indoor horticulture often accelerate lower-leaf chlorophyll degradation, increasing trimming frequency, reducing effective photosynthetic area, and raising labor costs. While spectral composition has been widely…
View details →Hali, Mahmoudi, Namdar et al. · 2026 · Dental research journal
Laser therapy with fluoride-containing material, such as casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), is a new technique for caries prevention. The purpose of this study is to investigate the effect of CPP-ACP, fluoride…
View details →Yang, Zhu, Chen et al. · 2026 · Frontiers in neuroscience
To observe the therapeutic effects of deep transcranial magnetic stimulation (dTMS) and repetitive transcranial magnetic stimulation (rTMS) on upper and lower limb motor dysfunction in patients with basal ganglia infarction, and to…
View details →Yao, Fang, Xu et al. · 2026 · Frontiers in medicine
To investigate the discrepancies between fall risk and fall awareness among hospitalized elderly cataract patients, providing a basis for implementing precise fall prevention assessments and interventions in clinical practice. Using…
View details →Yu, Li, Cai et al. · 2026 · Frontiers in medicine
This study directly compares the diagnostic performance of two routinely available, non-invasive techniques-ultrasound-derived fat fraction (UDFF) and non-contrast computed tomography (NCCT)-for screening and grading hepatic steatosis…
View details →Mahmoud, Elrefaei, Shata et al. · 2026 · Frontiers in oral health
The literature regarding the use of injectable platelet- rich fibrin (i-PRF) for root coverage is scarce. Therefore, this RCT aimed to evaluate and compare the effect of using connective tissue graft (CTG) with and without i-PRF using the…
View details →Fu, Yao, Zhang et al. · 2026 · Frontiers in cardiovascular medicine
The safety of achieving ultra-low low-density lipoprotein cholesterol (LDL-C) levels in acute coronary syndrome (ACS) patients on dual antiplatelet therapy (DAPT), particularly regarding global coagulability, specific platelet reactivity,…
View details →Kurokawa, Taniguchi, Nakaniwa et al. · 2026 · Foot & ankle orthopaedics
Varus-type ankle osteoarthritis (OA) is often managed conservatively; however, surgical intervention is required in some patients. Identifying factors associated with transition to surgery may help optimize treatment timing. This…
View details →Cui, Liang, Feng et al. · 2026 · Journal of bone and joint infection
Background : Periprosthetic joint infection (PJI) is a devastating complication of arthroplasty and is difficult to diagnose accurately. This study aims to explore the value of neutrophil extracellular traps in synovial fluid (SF-NETs,…
View details →Guo, Cao, Xiao et al. · 2026 · Plants (Basel, Switzerland)
Grain for Green, as an important ecological restoration method, profoundly affects soil nitrogen (N) cycling by altering the soil physicochemical properties and microbial community. Soil nitrogen mineralization is a key process in the…
View details →Cheng, Zhao, Li et al. · 2026 · Plants (Basel, Switzerland)
Plasma membrane intrinsic proteins (PIPs), a subfamily of aquaporins (AQPs), play critical roles in various physiological processes in plants, including the transport of water and CO 2 , regulation of stomatal movement, absorption of…
View details →Ma, Zhang, Yuan et al. · 2026 · Plants (Basel, Switzerland)
In rocky mountainous regions characterized by shallow, barren soils and water scarcity, non-rainfall water, such as condensation, plays a crucial ecological role in mitigating seasonal drought in forest trees. To enhance the water-use…
View details →Zhang, Wang, Tong et al. · 2026 · Sensors (Basel, Switzerland)
This study aimed to compare the neuromuscular control characteristics of international- and national-level squash players during forehand strokes using a multichannel surface electromyography (sEMG)-based sensing framework. By integrating…
View details →Hammer, Reiser, Bader et al. · 2026 · Nutrients
Boswellia serrata has traditionally been used in Ayurvedic medicine for its anti-inflammatory and antioxidant properties. Although several studies support clinical analgesic efficacy, the underlying mechanisms have not been investigated in…
View details →Jung, Lee, Jung et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Atelocollagen, a purified collagen derivative, has demonstrated potential benefits in various orthopedic applications; however, its role in anterior cruciate ligament (ACL) reconstruction remains unclear. This…
View details →Kim, Hong, Lee · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Surfactant protein B (SFTPB) is a surfactant-associated protein secreted by alveolar type II epithelial cells that plays a critical role in maintaining alveolar stability and surface tension. Although SFTPB is…
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