Advances in the intrinsic signaling pathway interactions and clinical translation of HR+/HER2+ breast cancer
Xinyu Li; Tao Huang · 2025 · Breast Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Hormone receptor-positive (HR +) and HER2-positive (HER2+) breast cancers represent a biologically unique subset of breast malignancies characterized by the co-expression of estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptor 2 (HER2). These cancers exhibit distinct molecular features, often leading to aggressive growth and higher recurrence rates. HR+/HER2+ breast cancer cells can utilize estrogen and HER2-driven signaling pathways to promote proliferation, survival, and metastatic potential, presenting unique challenges and opportunities for treat
Abstract by Xinyu Li; Tao Huang, Breast Cancer (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1007/s12282-025-01779-3