e-ISSN: Pending
WASTE Journal

Browse the failure-mode index

11,326 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Association between Helicobacter pylori infection and thyroid dysfunction in adults visiting a tertiary care hospital in Karachi, Pakistan: a cross-sectional study.

Jahangeer A, Jabeen R, Fatima S et al. · 2026 · BMC endocrine disorders

Background Thyroid dysfunction and Helicobacter pylori (H. pylori) infection are both highly prevalent in Pakistan. Several studies have proposed a potential immunological link between H. pylori infection and autoimmune thyroid disease,…

View details →
Negative / Null Result ReportOpen accessMedicine

Immunohistochemical expression of Stomatin-Like protein 2 and trophoblast cell surface antigen 2 in papillary thyroid carcinoma in comparison to other thyroid lesions.

Elmetwally AA, Khashaba MH, Wagih HM et al. · 2026 · Diagnostic pathology

BACKGROUND: Thyroid carcinoma is a common tumor affecting the Egyptian population accounting for 2% of newly diagnosed cases of cancer in Egypt yearly and constituting 7.73% of 5 year prevalence in Egypt. Stomatin-Like Protein 2 (SLP-2)…

View details →
Negative / Null Result ReportMedicine

The Association Between the STOP-Bang Score and the Integrated Pulmonary Index in Patients Undergoing Endobronchial Ultrasound with Sedation: The STOP OSA-IPI Cohort Study.

Ozden Sertcelik U, Turker M, Sertcelik A et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Perspectives : Obstructive sleep apnea (OSA) is a prevalent condition associated with increased perioperative risks. Endobronchial ultrasound (EBUS), a diagnostic and staging procedure requiring deep sedation, may pose…

View details →
Negative / Null Result ReportMedicine

Study of phosphorylated ribosomal protein S6 (pS6) in the clinical outcomes of patients undergoing hepatectomy for metastatic colorectal cancer.

Henriques Cavalcanti Torres de Melo R, de Barros Silva PG, Neto HFEC et al. · 2026 · World journal of surgical oncology

Introduction Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide, with up to 50% of patients developing metastatic disease, predominantly involving the liver. Hepatectomy remains the gold standard for resectable…

View details →
Negative / Null Result ReportMedicine

Mechanical diagnosis and therapy as a clinical diagnostic approach in lumbar disc herniation: association with radiological findings.

Aghdasi Z, Negahban H, Movahedi Aliabadi M et al. · 2026 · The Journal of manual & manipulative therapy

Background Lumbar disc herniation (LDH) is a leading causes of low back pain (LBP). Conservative approaches, such as the McKenzie Method of Mechanical Diagnosis and Therapy (MDT), are widely used as first-line treatments. MDT is based on…

View details →
Negative / Null Result ReportMedicine

The Association of G Protein-Coupled Estrogen Receptor (GPER) Polymorphisms with Ionizing Radiation Exposure in Healthcare Workers.

Öztürk Ü, Kurutaş EB, Üremiş N et al. · 2026 · Journal of clinical medicine

Background/Objectives: The G protein-coupled estrogen receptor (GPER) is known to interact with cellular stress responses and DNA damage pathways. Therefore, exposure to ionizing radiation may modulate the biological consequences of…

View details →
Negative / Null Result ReportMedicine

Impact of Preoperative Depression on Motor Recovery Following Brachial Plexus Reconstruction: A 24-Month Prospective Cohort Study.

Jianmongkol S, Wattanakamolchai S, Wainipitapong S et al. · 2026 · Hand (New York, N.Y.)

Background Depression is frequently diagnosed in patients experiencing traumatic injury and chronic neuropathic pain. Psychological factors may undermine patient motivation, potentially adversely affecting surgical outcomes. This study…

View details →
Negative / Null Result ReportMedicine

Independent and joint associations of social participation and depressive symptoms with incident stroke risk in older adults: a prospective cohort study based on CHARLS and ELSA.

Ma L, Ma Y, Huang Z et al. · 2026 · BMC public health

Stroke remains a leading cause of death and disability among older adults. Depressive symptoms and low social participation have been linked to stroke risk via behavioral and biological pathways. This study examined the independent and…

View details →
Negative / Null Result ReportMedicine

A Pilot Study Investigating the Clinically Significant Association Between Overweight, Hyperlipidemia, and Insulin Resistance in Dogs With Chronic Liver Disease.

Cogozzo A, Habermaass V, Dini R et al. · 2026 · Veterinary medicine international

The liver plays a central role in glucose and lipid metabolism. In human medicine, glucose metabolism alterations and insulin resistance are commonly associated with chronic liver disease (CLD), particularly in metabolic…

View details →
Negative / Null Result ReportMedicine

Overutilization of helicopter emergency medical services compared to ground transport in moderate-severe penetrating abdominal trauma & associated outcomes.

Hus A, Brown A, Bundschu I et al. · 2026 · Injury

Background Helicopter emergency medical services (HEMS) play a crucial role in trauma transport, accounting for approximately 550,000 transportations annually. However, HEMS holds a disproportionate share of trauma causes, highlighting its…

View details →
Negative / Null Result ReportMedicine

Association between adherence to the Dietary Approaches to Stop Hypertension diet and depression and anxiety severity in the Mashhad Stroke and Heart Atherosclerotic Disorder study population.

Soltani S, Rahimi HR, Seifi N et al. · 2026 · Public health nutrition

Objective The present study aimed to investigate the association between adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and the risk of depression and anxiety severity in a large group of Iranian adults. Design In…

View details →
Negative / Null Result ReportMedicine

Associations of Pregnancy History and Complications with Cardiovascular Disease Among American Indian Women: The Strong Heart Family Study.

Ebadani L, Reese JA, Sitlani CM et al. · 2026 · Journal of women's health (2002)

Introduction In the United States, cardiovascular disease (CVD) is a leading cause of death among American Indian women. We examined the associations of parity and pregnancy complications (history of preeclampsia, protein in urine,…

View details →
Negative / Null Result ReportMedicine

Association of IL-18 gene variants with depressive symptoms and metabolic syndrome in Mexican adults.

Ramirez De Los Santos ML, Ramírez-De Los Santos S, Becerra Solano LE et al. · 2026 · Nutricion hospitalaria

Introduction Introduction: metabolic syndrome (MS) affects approximately 27 % of the global population and represents a growing public health concern. Identifying factors associated with its presence is essential for prevention, early…

View details →
Negative / Null Result ReportOpen accessMedicine

Factors Affecting Country Differences in the Incidence of Type 2 Diabetes Mellitus Based on the Global Burden of Disease Data 2021: A Multilevel Longitudinal Ecological Study.

Jaafari Z, Hassanzadeh J, Sayadi M et al. · 2026 · Health science reports

Background and aims The variation in the incidence of type 2 diabetes mellitus (T2DM) in different countries is associated with various factors. This study aimed to examine the factors linked to the difference in the incidence of T2DM…

View details →