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Browse the failure-mode index

11,419 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The Effect of Isotonic Versus Isometric Strength Exercise for Pain and Strength in Proximal Hamstring Tendinopathy: A Randomized Crossover Trial.

Rich, Ford, Cook et al. · 2026 · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

The effect of isometric exercise on pain and strength for various tendinopathies has been investigated but there are no published studies on proximal hamstring tendinopathy (PHT). The objective of this trial was to determine the…

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Negative / Null Result ReportMedicine

Multiparametric MRI-Based Habitat Radiomics Combined with Deep Transfer Learning for Predicting Extrathyroidal Extension in Papillary Thyroid Carcinoma.

Li, Zeng, Wang et al. · 2026 · Journal of imaging informatics in medicine

The objective of the study is to develop and validate a multiparametric MRI (mpMRI)-based model that integrated with habitat-based radiomics, deep transfer learning (DTL), and quantitative parameters for the preoperative prediction of…

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Negative / Null Result ReportMedicine

Early orthodontic traction does not compromise root development in inversely impacted maxillary central incisors: a three-year cone-beam computed tomography evaluation.

Yang, Dong, Cheng et al. · 2026 · Clinical oral investigations

To evaluate whether early orthodontic traction of inversely impacted maxillary central incisors with curved roots affects subsequent root development and labial/palatal alveolar bone support. A retrospective cone-beam computed tomography…

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Negative / Null Result ReportMedicine

Venous thromboembolic events in traumatic brain injury. Does timing of prophylaxis matter? A single-center retrospective cohort study.

Hernandez, Christensen, Shumaker et al. · 2026 · Proceedings (Baylor University. Medical Center)

Patients with traumatic brain injury (TBI) are at increased risk for venous thromboembolism (VTE) due to immobilization and a hypercoagulable state. The administration and optimal timing for chemoprophylaxis remain unclear because of…

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Negative / Null Result ReportMedicine

Phacoemulsification with IOL implantation combined with goniosynechialysis and goniotomy in primary angle-closure glaucoma following failed trabeculectomy: short-term effectiveness and safety outcomes.

Zhou, Ge, Jin et al. · 2026 · Frontiers in medicine

To evaluate the short-term effectiveness and safety of Phacoemulsification with intraocular lens implantation combined with goniosynechialysis and goniotomy (PEI-GSL-GT) in eyes with prior failed trabeculectomy compared to surgically…

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Negative / Null Result ReportMedicine

Efficacy and cost-effectiveness of intraoperative cell salvage for patients with placenta previa during cesarean section: a retrospective comparison analysis.

Zhang, Lu, Hua et al. · 2026 · Open medicine (Warsaw, Poland)

This study aimed to evaluate whether intraoperative cell salvage (ICS) and retransfusion reduce allogeneic blood transfusion (ABT) requirement and treatment costs in patients with placenta previa undergoing cesarean section. We…

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Negative / Null Result ReportMedicine

Endoscopic versus open flexor hallucis longus tendon transfer for reconstruction of chronic achilles tendon rupture: A prospective randomized pilot trial.

Afifi, Hewaidy, El Shazly et al. · 2026 · Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons

Chronic Achilles tendon rupture often requires surgical reconstruction. Flexor hallucis longus (FHL) tendon transfer is widely used, and endoscopic techniques may reduce soft-tissue morbidity and facilitate early recovery. Thirty patients…

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Negative / Null Result ReportMedicine

Valorization of Sour Cherry Seeds in Beef Meatballs: Effect on Quality, Lipid Oxidation, Texture Profile, Acrylamide Formation and Antioxidant Activity.

Savaş, Kavrut, Engin · 2026 · Foods (Basel, Switzerland)

In the study, the effects of adding sour cheery seed powder at different concentrations (0%, 0.5%, 1%, and 1.5%) on the pH, water content, lipid oxidation, cooking loss, color, TPC, antioxidant activity (DPPH and ABTS), texture, and…

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Negative / Null Result ReportMedicine

Persistent deficits in the motor unit following mono and dual administration of SMN up-regulators in the SmnΔ7 mouse model of spinal muscular atrophy.

Partlova, Comley, Haigh et al. · 2026 · Experimental neurology

Spinal muscular atrophy (SMA) is characterized by motor neuron loss and neuromuscular junction (NMJ) pathology. Although SMN-upregulating therapies such as Nusinersen markedly improve survival and motor function for many patients,…

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