11,325 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Mulay, Bhansali, Indurkar et al. · 2026 · Bioinformation
Early achievement of optimal interdental papilla fill around dental implants remains a clinical challenge affecting aesthetic outcomes in single-tooth replacement. Therefore, it is of interest to compare interdental papilla fill around…
View details →Fukushi, Emori, Tsuchie et al. · 2026 · Cureus
Aggressive surgical resection with adequate margins is associated with improved local control and survival in selected patients with primary spinal sarcomas. However, anatomical constraints often preclude complete resection, and outcomes…
View details →Benson, Gomez, DerAshodian et al. · 2026 · Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
This study examines disability-related disparities in tooth loss and dental visits, and Medicaid dental service utilization across Nevada counties in 2022. A cross-sectional analysis of the 2022 Behavioral Risk Factor Surveillance System…
View details →Rode, Wolf, Bolan et al. · 2026 · Childhood obesity (Print)
This clinical trial evaluated hepatic fat content and weight loss in adolescents with severe obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) following short-term meal replacement therapy (MRT). Adolescents aged…
View details →Kohzai, Yamamoto, Matsushita et al. · 2026 · Diagnostics (Basel, Switzerland)
Objectives : Whereas irreversible compression of Digital Imaging and Communications in Medicine (DICOM) files can reduce data size, research on its impact on diagnostic ability when using artificial intelligence (AI) software is limited.…
View details →Bosbach, Montazeri, Senge et al. · 2026 · Diagnostics (Basel, Switzerland)
Purpose: Large language models (LLMs) may reduce administrative workload in radiology by automating structured diagnostic extraction from text reports. This study evaluates the accuracy of ChatGPT-4.0 when extracting correct diagnoses from…
View details →Paternostro, Joura, Postl et al. · 2026 · Journal of clinical medicine
Background/Objectives: Large loop excision of the transformation zone (LLETZ) is used as a standard treatment for cervical dysplasia. Although obesity is associated with reduced cervical screening participation and may complicate…
View details →Astan, Balta, Zengin et al. · 2026 · Journal of clinical medicine
Background/Objectives: Paprosky Type IIC acetabular defects encountered during revision total hip arthroplasty (rTHA) present substantial challenges in terms of surgical planning and implant stability. This study evaluates the outcomes of…
View details →Wegner, Warnke, Buschmann et al. · 2026 · Journal of clinical medicine
Background/Objectives : Post-traumatic joint contracture (PTJC) is a common complication in orthopedic surgery characterized by fibrosis and restricted joint mobility. Previous work by our multi-arm study demonstrated that nintedanib…
View details →Ozalp, Yolcu, Uyar et al. · 2026 · Journal of clinical medicine
Background: The erector spinae plane block (ESPB) is a commonly used interventional method in the treatment of post-herpetic neuralgia (PHN). ESPB can be performed under the guidance of ultrasound or fluoroscopy, and there are limited data…
View details →Merluzzi, Lepri, Lidano et al. · 2026 · Animals : an open access journal from MDPI
The Anatomage Table Vet (ATV) is a digital tool that may facilitate the understanding of complex structures and improve visuospatial skills. This study evaluated the effectiveness of the ATV as a review method prior to cadaveric dissection…
View details →Fu, Xiao, Ma et al. · 2026 · Animals : an open access journal from MDPI
Digestive tract structure is a key indicator of fish health and environmental adaptation, while seasonal dynamics of the gut microbiota reflect host responses to environmental changes. In this study, the digestive tract microstructure of…
View details →Moosavi, Khorakian, Sedaghati et al. · 2026 · BMC oral health
Severe caries in mixed dentition frequently affects mandibular first permanent molars, often necessitating full-coverage restorations. Stainless steel crowns (SSCs) and porcelain-fused-to-metal (PFM) crowns are among the most commonly used…
View details →Yue, Kong, Huang et al. · 2026 · BMC cancer
The optimal timing for thermal ablation (TA) in patients with colorectal liver metastases (CRLM) eligible for local curative therapy remains undefined. This study aimed to evaluate the impact of time to ablation (TTA) on long-term survival…
View details →Roberts, Waddell, Atkins et al. · 2026 · The New Zealand medical journal
Our aim was to determine the 30- and 90-day all-cause mortality of healthcare-associated Staphylococcus aureus bacteraemia (HA-SAB) and determine mortality risk factors. We collected HA-SAB events from 1 July 2022 to 30 June 2024. Patient…
View details →McFarland, Sihra, Walker et al. · 2026 · Journal of racial and ethnic health disparities
To evaluate Black birthing people's knowledge of American Academy of Pediatrics (AAP) infant safe sleep recommendations over time in the context of a substantial, county-wide, tailored public health initiative against infant mortality.…
View details →Benyamini, Khan, Elmenawi et al. · 2026 · Hip international : the journal of clinical and experimental research on hip pathology and therapy
Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly utilised for metabolic optimisation in surgical patients. Their effect on postoperative patient-reported outcomes (PROMs) and satisfaction following primary total hip…
View details →Rajvanshi, Kumar, Goyal et al. · 2026 · Pediatric pulmonology
Flexible fibreoptic bronchoscopy (FFB) is widely used in pediatric pulmonology, though hypoxemia remains a primary concern during the procedure. High-flow nasal cannula (HFNC) has shown potential in reducing hypoxemia in adults undergoing…
View details →Dhakar, Ghori, Parihar et al. · 2026 · The Gulf journal of oncology
Oral cavity cancers often require radiotherapy (RT), leading to toxicities such as xerostomia, skin reactions, and mucositis. This study aims to compare these toxicities between three-dimensional conformal radiotherapy (3D-CRT) and…
View details →Granfeldt, Kirkegaard, Vallentin et al. · 2026 · JAMA
Patients with in-hospital cardiac arrest have poor outcomes. Sodium bicarbonate is commonly administered during cardiac arrest, but the effects on clinical outcomes are unknown. To determine whether administration of sodium bicarbonate…
View details →Itoh, Iseda, Yoshizumi et al. · 2026 · Cancer medicine
We examine the impact of interferon (IFN)-based and IFN-free treatment on the prognosis of hepatocellular carcinoma (HCC) after hepatitis C virus (HCV) sustained virological response (SVR). Clinical information was collected on 311 cases…
View details →Naoumova, Nawaia, Krekmanova · 2026 · European journal of orthodontics
Extraction of mandibular primary second molars in patients with congenitally missing second premolars may influence oral health-related quality of life (OHRQoL), yet this has not been previously investigated. To assess the impact of…
View details →Tsujimoto, Yamashiro, Suzuki et al. · 2026 · International journal of endocrinology
Adult growth hormone deficiency (AGHD) is often diagnosed after surgery for nonfunctioning pituitary neuroendocrine tumor (NF-PitNET). While a growth hormone stimulation test (GHST) is required to establish its diagnosis, it is associated…
View details →Fukue, Suetomi, Matsuura et al. · 2026 · Circulation reports
As part of work-style reform for physicians, task shifting to non-physician healthcare professionals has been promoted in Japan. We previously reported task shifting results for percutaneous coronary interventions (PCI), but the status in…
View details →Tomita, Kakuta, Kainuma et al. · 2026 · Circulation reports
Robotic mitral valve repair (MVr) offers superior visualization and dexterity, potentially overcoming challenges in severe thoracic deformity such as pectus excavatum. This study compared surgical outcomes after MVr in patients with and…
View details →Liu, Xiang, Li et al. · 2026 · Frontiers in psychology
To better serve the best interests of minors, there is a growing consensus on the need for differentiated correction approaches for juvenile offenders based on their classifications. To implement these tailored interventions, it is…
View details →Ranabothu, Smith, Perkins et al. · 2026 · Pediatric transplantation
Pediatric kidney transplant recipients typically receive low-KDPI deceased donor kidneys but often experience higher HLA mismatches. The relationship between KDPI and HLA mismatch and their combined effect on graft and patient outcomes in…
View details →Kamagaté, Jusot, Mory et al. · 2026 · Therapeutic advances in drug safety
In Côte d'Ivoire, pharmacovigilance is not a routine activity in most healthcare facilities and many healthcare professionals have limited knowledge of pharmacovigilance methods. This study aimed to evaluate the quality of adverse…
View details →Saeed, Jalal · 2026 · Pulmonary medicine
The COVID-19 pandemic, caused by SARS-CoV-2, has led to significant global mortality and morbidity. Angiotensin-converting Enzyme 2 (ACE2) has been identified as the primary receptor for viral entry into host cells and is believed to play…
View details →Mohammed, Naser, Abozaid · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
Composite resin placement technique may influence marginal integrity, polymerization stress distribution, and long-term clinical performance of posterior restorations. This randomized controlled clinical trial evaluated the 24-month…
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