Prophylactic Effects of Combined Bosentan and Nintedanib on Early Post-Traumatic Joint Contracture Formation in a Rat Model.
Wegner; Warnke; Buschmann; Pirkl; Betz; Ritz; Mühlschlegel; Dietz · 2026 · Journal of clinical medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background/Objectives : Post-traumatic joint contracture (PTJC) is a common complication in orthopedic surgery characterized by fibrosis and restricted joint mobility. Previous work by our multi-arm study demonstrated that nintedanib…
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Metadata source: PubMed · DOI 10.3390/jcm15114116