11,325 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Umer H, Mumtaz T, Weiskirchen R et al. · 2026 · Chronobiology international
Disruption of circadian rhythm is common in rotating shift workers, individuals with jet lag, and people with irregular sleep schedules and contributes to metabolic diseases including obesity, type 2 diabetes, metabolic…
View details →Liu Y, Tao G, Zhao Y et al. · 2026 · Frontiers in medicine
Objective To characterize choroidal structural and perfusion changes in children with emmetropia, low myopia, and moderate myopia using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography…
View details →Kurogochi K, Stern JA, DeFrancesco TC et al. · 2026 · Journal of the American Veterinary Medical Association
Objective The T-wave peak-end (TpTe) interval and its ratio to the QT interval (TpTe:QT) are ECG markers of myocardial repolarization dispersion. We hypothesized that these markers are associated with echocardiographic indices reflecting…
View details →Eydou Z, Garber S, Sikkema M · 2026 · Cureus
Fusobacterium necrophorum is a recognized cause of brain abscesses and has been classically associated with Lemierre syndrome. We report a case of a 17-year-old male patient who presented with seizures, fever, and altered mental status…
View details →Boualia B, Sandeli A, Boulebd H et al. · 2026 · ACS omega
In this research, we present the successful synthesis of benzimidazolium salts ( 2a - e ) and their corresponding selenium-NHC adducts ( 3a - e ), achieved with satisfactory yields ranging from 75% to 88%, and characterized using…
View details →Qaid MM, Al-Garadi MA, Al-Abdullatif AA et al. · 2026 · Poultry science
Coccidiosis remains a major constraint in poultry production; therefore, this study evaluated the anticoccidial efficacy of a phytogenic blend of cinnamon bark and Rumex nervosus leaf in Eimeria tenella-challenged broilers. Birds were…
View details →Hayashi E, Kano H, Nakamura K et al. · 2026 · Respirology case reports
Small-cell lung cancer (SCLC) has a poor prognosis, and the efficacy of tarlatamab for untreated brain metastases remains unclear. We report a case demonstrating a discrepant response between extracranial and intracranial lesions after…
View details →Wei X, Xue M, Fan B et al. · 2026 · BMC pulmonary medicine
Background Long-term changes in lung function in children with symptom control asthma are rare. To assess the trajectory of pulmonary function in children and analyze the influence factors. Methods The effects of gender, age, Body Mass…
View details →Eltahir M, Young K, Younes S et al. · 2026 · American journal of clinical pathology
Objectives Determination of B-cell clonality in formalin-fixed, paraffin-embedded tissues is challenging, especially in cases where tumor B cells are sparse. Flow cytometry is of limited utility in Hodgkin lymphomas, at least in part due…
View details →Hauck F, Herber V, Moecke S et al. · 2026 · International journal of oral implantology (Berlin, Germany)
Purpose The aim of this pilot preclinical study was to investigate the performance of a novel double-lead thread, conical bone-level ceramic implant manufactured by injection moulding (test group) in comparison to a well-established…
View details →Uğurlu İ · 2026 · Journal of clinical laboratory analysis
Background Apelin-13 and Galectin-3 (Gal-3) are bioactive mediators linked to inflammation and cardiometabolic pathways. Their clinical utility in COVID-19 alongside routine laboratory tests remains unclear. Methods In this case-control…
View details →Qian MY, He LY, Lan P et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
This study aimed to identify predictors of outcomes and evaluate the therapeutic impact of surgical intervention in CM patients, with a specific focus on the growing HIV-negative population in East Asia. We conducted a single-center…
View details →Fang H, Feng L, Gu M et al. · 2026 · Personality and mental health
Invalidating family environments are theorized to undermine youths' emotion socialization and confer risk for psychopathology, yet heterogeneity in how invalidation is expressed within families is rarely examined. This study employed…
View details →Katip A, Demiralp E · 2026 · Toxics
Industrial and domestic wastewaters, nonpoint pollution sources, and climate change affect stream ecosystems, water quantity, and quality. Within the scope of this study, the water quality of Nilüfer Stream was evaluated using the Water…
View details →Bakhshalizadeh S, Mora-Medina R, Ayala-Soldado N · 2026 · Animals : an open access journal from MDPI
Bivalves are widely used in aquatic monitoring, but the potential of their shells to provide comparative metal signatures remains insufficiently explored in the Caspian Sea. This study quantified major and trace elements in empty shells of…
View details →Alvina, Jaffar H, Onwuzo CN et al. · 2026 · Digestive diseases and sciences
Background Biliary adverse events (AEs) have been reported with glucagon-like peptide-1 receptor agonists (GLP-1RAs), but within-class differences remain unclear. Methods We conducted a disproportionality analysis of FAERS comparing…
View details →Ding J, Li X · 2026 · Biology
Soil depth and habitat degradation can reshape fungal communities in salt-affected wetlands, but their effects on fungal ecological processes remain insufficiently understood. This study examined soil fungi in the Halahai Provincial Nature…
View details →Zaini AZ, Loganathan T, Danaee M et al. · 2026 · Journal of racial and ethnic health disparities
Background Equitable healthcare access is a key aspect of health equity, yet migrants face substantial barriers. In Malaysia, migrant workers encounter structural and socio-economic barriers to healthcare. Acculturation and social support…
View details →Nagakura Y, Yamaki F, Saimaru H et al. · 2026 · Currents in pharmacy teaching & learning
Introduction In Japanese pharmacy education, success on the National Pharmacist Examination is a key objective. This study evaluated learning gain across face-to-face, mixed-attendance, and live online participation patterns in a…
View details →Long CY, Chang CY, Sung IC et al. · 2026 · Frontiers in bioengineering and biotechnology
Background Interstitial cystitis (IC) is a disease comprised of multiple symptoms, included persistent bladder pain syndrome (BPS), frequent urination, and urgency without getting infection or other identifiable causes. Methods In our…
View details →Li L, Wang C, Ji Y et al. · 2026 · Behavioral sciences (Basel, Switzerland)
Previous research suggests receiving a concurrent auditory version of text during reading, i.e., reading-while-listening, improves eye-movement behavior in less skilled readers, while disrupting skilled reading. We extended this approach…
View details →Seiser M, Deininger C, Fierlbeck J et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Purpose External fixators are essential for the surgical management of long-bone fractures, particularly in resource-limited settings where access to commercial systems is often restricted by cost and logistics. This study aimed to develop…
View details →Batool SM, Lee H, Muralidharan K et al. · 2026 · Cancers
Characterizing the m6A epigenetic landscape is essential for understanding glioma biology, yet transcriptome-wide mapping of these modifications at isoform resolution across specific tumor subtypes has remained limited. Conventional…
View details →Chen Y, Gao L, Zheng Z et al. · 2026 · Scientific reports
Preoperative decision-making regarding extended pelvic lymph node dissection (ePLND) in prostate cancer remains challenging. Existing nodal-risk prediction tools are mainly based on clinicopathologic variables and may show suboptimal…
View details →Alghonemy WY, Ahmed NM, Abou Samra AA et al. · 2026 · Journal of oral biology and craniofacial research
Objective To evaluate the regenerative effects of platelet-rich plasma (PRP) combined with 3% low-molecular-weight hyaluronic acid (HA) gel in treating ligature-induced periodontitis in rats. Methods •40 male albino rats divided into 5…
View details →Selim AAMA · 2026 · Natural product research
Three hydrazone chromones 3a-c ( 3a, b in trans isomer while 3c was a mixture) and three hydrazone furanochromones 7a-c ( 7a in trans while 7b, c in cis ) carrying carboxylic acid or its bioisostere sulphonamide group were synthesised.…
View details →Chen L, Liang W, Guo Y et al. · 2026 · Biomedical chromatography : BMC
Paeoniae Radix Alba (PRA, roots of Paeonia lactiflora Pall.) yields stir-baked (sbPRA), charred (cPRA), and carbonized (caPRA) specifications through increasing degrees of stir-baking. In this study, an ultrahigh-performance liquid…
View details →Omran SA, Elnaggar MS, Youssef FS et al. · 2026 · Natural products and bioprospecting
Marine-derived Penicillium fungus gained significant attention in recent years due to their potential as a valuable source of unique natural compounds with a wide range of chemical structures and bioactive capabilities. The primary origins…
View details →Feng K, Bao Y, Ren J et al. · 2026 · Life (Basel, Switzerland)
MicroRNA (miRNA) regulation plays a pivotal role in intracellular gene expression. Analysis of miRNA profiles can provide critical insights into disease states. As cancer-associated molecules reported in previous studies, miRNAs may serve…
View details →Khan H, Collela Be M, Khan Z et al. · 2026 · BMC plant biology
Background Sowing period has a considerable effect on cotton productivity by regulating the use of thermal resources, but its effect on various soils depth layers has not been properly measured. The current study investigated the impacts…
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