11,324 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Tissink, Timmerman, Vermeer et al. · 2026 · PloS one
Recurrent weight gain remains a challenge in metabolic bariatric surgery (MBS). Recent publications focused on ring-augmented Roux-en-Y gastric bypass (RYGB) and ring-augmented sleeve gastrectomy (SG), but few studies have addressed the…
View details →Tsai, Li, Hsu et al. · 2026 · PloS one
Prostatic abscess, which is an uncommon urinary tract disease, can lead to mortality if not properly treated. This retrospective study aimed to identify risk factors associated with mortality in patients with prostatic abscess, with the…
View details →Shamsoddini, Cheraghifard · 2026 · European geriatric medicine
Balance issues and the fear of falling are among the primary factors contributing to falls in older people, leading to injury and a decline in quality of life. A single-blind, randomized, controlled trial was conducted involving 34 older…
View details →Kaman, Stork, Okumus et al. · 2026 · Langenbeck's archives of surgery
Segmentectomy is offered in selected patients with clinical T1a-b N0 M0 lung cancer. In case of positive N1 lymph node at fresh frozen section, conversion to lobectomy is recommended. Indication for redo surgery and completion lobectomy in…
View details →Wang, Xiao, Li et al. · 2026 · Frontiers in pharmacology
Inferior ST-segment elevation myocardial infarction (STEMI) complicated by right ventricular involvement (RVMI) leads to right-heart-dominant failure and a higher incidence of cardiogenic shock (CS). Evidence guiding the choice between…
View details →Larréché, Sodjinou, Tourita et al. · 2026 · Medecine tropicale et sante internationale
Hemorrhagic syndrome accounts for a significant proportion of the mortality and morbidity associated with snakebites in sub-Saharan Africa. Hyperfibrinolysis, which has been reported in some cases, suggests the potential benefit of…
View details →Papale, Festino, Di Rocco et al. · 2026 · Biology of sport
Although there is a trend toward outdoor activities, limited research has examined the effects of outdoor exercise on blood pressure. This study aimed to compare the Systolic (sBP) and Diastolic (dBP) Blood Pressure, Heart Rate (HR)…
View details →Yang, Dong, Song et al. · 2026 · Current medical imaging
The thymic veins are small vessels located in the anterior superior mediastinum, and thymic tissue undergoes physiological degeneration with age. Multidetector computed tomography (MDCT) with isotropic resolution allows comprehensive…
View details →Larkin, Schiavon, Hajihassani · 2026 · Plant disease
In South Florida, the development and maintenance of high-quality golf courses are important to the state's economy. The courses, however, are commonly affected by plant-parasitic nematodes (PPNs), which are highly damaging. Effective…
View details →Elenjickal, Baroz, Boileau et al. · 2026 · Diabetes, obesity & metabolism
Pharmacokinetic data suggest a potential dose-dependent effect of sodium-glucose co-transporter-2 (SGLT-2) inhibitors on surrogate markers of efficacy, but the impact of SGLT-2 inhibitor dose on renal and cardiovascular outcomes remains…
View details →Wilcox, Campbell, Gill et al. · 2026 · The bone & joint journal
Computer navigation is capable of improving the accuracy of glenoid baseplate and screw positioning in shoulder arthroplasty, but there is very limited evidence of its effect on clinical outcomes. In Australia, there is one commonly used…
View details →Metter, Dumoulin, Hay et al. · 2026 · Scandinavian journal of gastroenterology
Endoscopic submucosal resection (ESR) is a novel resection technique. ESR is performed with a partially insulated snare, which allows a resection close to the proper muscle layer thus resecting in the deep submucosa. This should have…
View details →García Alcaide, Conde Villar, Pérez Alfayate et al. · 2026 · European journal of dental education : official journal of the Association for Dental Education in Europe
To assess the impact of a tailored ergonomic lecture on postural risk among second-year endodontic residents depending on the use of no magnification, ergonomic loupes, or an operating microscope. A within-subjects, repeated measures…
View details →Qiao, Wang, Liu et al. · 2026 · BMC surgery
To evaluate the impact of sodium carboxymethyl cellulose (SCMC)-based absorbable hemostatic gauze on postoperative infectious outcomes in emergency laparoscopic appendectomy (LA) for acute appendicitis. A retrospective analysis of 184…
View details →Herzog, Brink, Gondalia et al. · 2026 · Sports medicine (Auckland, N.Z.)
One often-stated aim of load management in elite athletes is injury reduction. However, current literature on the efficacy and effectiveness of specific load management strategies to reduce injury risk is limited. The aim of this study was…
View details →Wang, Liu, Wang et al. · 2026 · Journal of neuro-oncology
H3K27M-mutant diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brainstem tumor with a median overall survival (OS) of less than one year. Radiotherapy (RT) is the standard treatment, but the survival benefit of adding…
View details →Prasert, Praphasiri, Ditsungnoen et al. · 2026 · The Journal of infectious diseases
Antigenically drifted influenza A(H3N2) subclade K viruses have contributed substantially to influenza burden since 2025, but their clinical severity is less well described. Using sentinel surveillance data from Thailand, we found no…
View details →Keskin, Erdoğan, Küçükçetin et al. · 2026 · Psychiatry research
The aim of this study was to compare serum levels of Fibroblast Growth Factor-2 (FGF-2) and Fibroblast Growth Factor-9 (FGF-9) between patients with Bipolar Disorder (BD) and healthy controls (HC), and to evaluate whether these molecules…
View details →Li, Zhu, Xu et al. · 2026 · Advances in therapy
This study evaluated the efficacy and safety of cipepofol vs. dexmedetomidine for long-term sedation of patients undergoing mechanical ventilation (MV) in an intensive care unit (ICU). Adult patients who required invasive MV for…
View details →Tan, Feng, Wen et al. · 2026 · Medicine
To investigate the effect of expressive writing intervention on optimism and coping modes of newly diagnosed people with human immunodeficiency virus (HIV). A total of 84 newly diagnosed people with HIV in the care clinic of Public Health…
View details →Tao, Pan, Li et al. · 2026 · BMC emergency medicine
The impact of Emergency Medical Service (EMS) on the prognosis of patients with acute ischemic stroke (AIS) remains controversial. This prospective cohort study enrolled AIS patients admitted to the emergency department of the Central…
View details →Sood, Turnbull, De Silva et al. · 2026 · Heart, lung & circulation
Improved patient outcomes after ventricular arrhythmia (VA) ablation procedure have been found to correlate with procedures being performed in high volume centres. Whether the concentration of expertise in experienced, urban centres…
View details →Cheng, Zhu, Xie et al. · 2026 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
This study aimed to explore the association between different stroke onset types [unwitnessed stroke (UWS) vs. witnessed stroke (WS)] and clinical outcomes in patients with large ischemic stroke treated with endovascular therapy (EVT).…
View details →Sinsareekul, Chantarangsu, Hiran-Us · 2026 · Journal of dentistry
This retrospective study aimed to evaluate the influence of sealer extrusion on treatment outcomes using a within-tooth comparative design and to identify associated prognostic factors. A total of 126 patients who underwent nonsurgical…
View details →Susma, Spronken, van Nieuwkoop et al. · 2026 · Journal of virology
Cytosine-phosphate-guanine (CpG) dinucleotide motifs are the most underrepresented motifs in RNA virus genomes, including those of the influenza A viruses (IAV). Previous studies have indicated that increasing the number of CpG motifs in…
View details →Adeoye, Ani, Egbokhare et al. · 2026 · Psychology, health & medicine
Sickle Cell Disorder (SCD) is a complex, multi-system blood condition affecting 7.78 million people, with 80% of global cases in sub-Saharan Africa, especially Nigeria. The condition is associated with physical health complications and…
View details →Kaewmanee, Ganesan, Choochana et al. · 2026 · PloS one
Phy-Blica-O (PBO) is a traditional Thai polyherbal formulation historically regarded as a brain tonic and memory enhancer. Despite its long-standing ethnomedicinal use, its neuroprotective mechanisms have not been scientifically validated.…
View details →Yamada, Hosokawa, Mitoma et al. · 2026 · Biological & pharmaceutical bulletin
Rheumatoid arthritis is characterized by chronic synovial inflammation and recurrent flares, which are thought to involve joint-specific inflammatory memory. Synovial fibroblasts (SFs) contribute to this process through altered responses…
View details →Jawahir, Balqis, Lee et al. · 2026 · BMJ open
Guided by the Andersen Behavioural Model of Healthcare Utilisation, this study investigated the relationship between socioeconomic status, enabling factors and need factors in predicting hospital admission. Data were analysed from the…
View details →Rostami, Ashraf, Hosseininasab · 2026 · Open heart
Chemotherapy-induced cardiotoxicity is a major contributor to long-term cardiovascular morbidity among cancer survivors. ACE inhibitors (ACEIs), angiotensin receptor blockers and beta blockers have been proposed as prophylactic therapies;…
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