11,324 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Lyu S, Wu Y, Dai Y et al. · 2026 · BMC women's health
Background Spontaneous ovarian endometrioma rupture typically presents with acute abdominal pain, a condition often complicated by tissue edema and pelvic adhesions that increase surgical difficulty. This study aims to evaluate the impact…
View details →Peker Y, Hjälm HH, Glantz H et al. · 2026 · Balkan medical journal
Background The relationship between obstructive sleep apnea (OSA) and coronary artery disease (CAD) remains controversial. Although observational studies have suggested that OSA is associated with an increased risk of coronary events,…
View details →Cao S, Ling M, Zhang X et al. · 2026 · BMC cardiovascular disorders
Background The safety of drug-eluting stents (DES) in patients undergoing percutaneous coronary intervention (PCI) remains largely lacking in China. This study aimed to determine the 1-year adverse outcomes in a large registry of patients…
View details →Veronesi R, Bozzini S, Dezza C et al. · 2026 · Perfusion
BackgroundOpen pulmonary endarterectomy (PEA) carries a high risk of neurological complications due to cerebral hypoperfusion and ischemia-reperfusion injury. Systemic cooling during extracorporeal circulation may not sufficiently reduce…
View details →Altintop I, Tatli M, Sarica ZS et al. · 2026 · Brain sciences
Background Contrast-induced encephalopathy (CIE) is an uncommon yet clinically significant complication associated with iodinated contrast media, with its mechanisms remaining unclear. Objective The aims of this study are to examine the…
View details →Jiang Y, Wang Z, Wen H et al. · 2026 · BMC anesthesiology
Background Drug-induced sleep endoscopy (DISE) is widely used to evaluate upper airway obstruction in patients with obstructive sleep apnea syndrome (OSAS). We aimed to compare the sedative efficacy and safety of esketamine combined with…
View details →İnan B, Erdoğan Ç, Keskin ET et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : This study investigated the prognostic value of two simple blood urea nitrogen (BUN)-based ratios, BUN/hemoglobin (Hb) and BUN/Albumin, for predicting in-hospital mortality and prolonged hospitalization in…
View details →Greța-Oanță AL, Roman A, Berindan-Neagoe I et al. · 2026 · Journal of clinical medicine
Background/Objectives: Bitter taste receptors (T2Rs), specifically T2R38, are present in the respiratory epithelium and react with bacterial quorum-sensing molecules to induce an innate immunity response. Although TAS2R38 polymorphisms…
View details →Japundža-Milisavljević M, Buha N, Milanović-Dobrota B · 2026 · Journal of applied research in intellectual disabilities : JARID
Background The study is based on the Dual Pathway to Creativity Model and explores the relationship between inhibitory control and creativity in children with mild intellectual disabilities. Method The sample consisted of 58 children with…
View details →Doganay D, Ismayilov AS, Sevınc D et al. · 2026 · Cutaneous and ocular toxicology
Purpose To evaluate the changes in aberrometry values on corneal topography and the function of the meibomian glands following therapeutic Botulinum toxin type A injections in patients with blepharospasm and hemifacial spasm. Materials and…
View details →Wang H, Wang W, Li Y et al. · 2026 · Animal reproduction science
This study aimed to examine the protective effects of kaempferol on the in vitro maturation (IVM) of bovine oocytes and their subsequent embryonic development, and to investigate the underlying mechanisms. Bovine oocytes were cultured with…
View details →Ariga A, Kubo N, Koizumi T et al. · 2026 · Food Quality and Preference.
Multisensory research has demonstrated that the perceptual characteristics of a receptacle can influence how beverages are experienced, a phenomenon known as sensation transference. Previous studies have shown that the lip thickness of a…
View details →Grande-Moreillo C, Pérez-López C, Vicente-Sánchez N et al. · 2026 · European journal of pediatrics
Acquired cryptorchidism is an increasingly recognized condition and may present bilaterally with a metachronous pattern. The objective of this study was to evaluate the incidence of acquired contralateral metachronous cryptorchidism and to…
View details →Zhao Z, Wu C, Fu S et al. · 2026 · World journal of urology
Purpose Benign prostatic hyperplasia (BPH) is a common age-related urological condition influenced by both modifiable lifestyle factors and genetic susceptibility. This large cohort study was performed to examine the association between…
View details →Sardar N, Raouf S, Bilal A et al. · 2026 · International urology and nephrology
Background Calcium oxalate (CaOx) nephrolithiasis is a recurrent urological disorder, and Randall's plaque (RP) of the renal papilla is widely accepted as an early site of stone nucleation. Although immune activation, epithelial injury,…
View details →Goyal A, Konieczny K, Plombon S et al. · 2026 · Journal of general internal medicine
Background Diagnostic errors (DEs) are a major threat to hospital patient safety. Identifying admission-based predictors associated with harmful DEs may help improve diagnostic safety in high-risk populations. Objective To assess the…
View details →Ciftci B, Karadag B · 2026 · International journal of women's health
Objective To evaluate the effectiveness of intrauterine hyaluronic acid (HA) gel application in preventing postoperative intrauterine adhesion formation following operative hysteroscopy. Methods This retrospective comparative study was…
View details →Yasmin F, Rab AU, Asghar MS et al. · 2026 · Journal of cardiothoracic surgery
Purpose Given the systemic nature of connective tissue diseases (CTD), open surgical intervention for aortic stenosis is often considered high risk, making transcatheter aortic valve replacement (TAVR) a potentially preferable alternative.…
View details →Nakamae A, Nekomoto A, Nakata K et al. · 2026 · The journal of knee surgery
Abstract This study aimed to identify factors associated with greater quantitative pivot shift in anterior cruciate ligament (ACL)-injured knees by quantitatively assessing the pivot shift under anesthesia using a navigation system prior…
View details →Cakir M, Buyuk C, Kan B · 2026 · The International journal of oral & maxillofacial implants
Purpose Achieving optimal primary stability is critical for dental implant success, particularly in low-density bone regions such as the posterior maxilla. Conventional high-speed drilling with irrigation may remove vital bone fragments…
View details →Kawaguchi M, Hoshina M, Sugahara S et al. · 2026 · Cureus
Objective This pilot study investigated the dosimetric impact of artificial intelligence (AI)-generated seminal vesicle (SV) autocontouring (AC) compared with manual contouring (MC) in high-risk prostate cancer volumetric-modulated arc…
View details →Erken AA, Dincer ST · 2026 · Asia-Pacific journal of clinical oncology
Aim Total neoadjuvant therapy has been adopted to improve systemic disease control in locally advanced rectal cancer, yet long-term real-world outcomes, particularly in non-Western populations, remain incompletely defined. We compared…
View details →Benedikt M, Herrmann M, Aziz F et al. · 2026 · Journal of clinical medicine
Background : Sodium glucose-linked transport 2 inhibitors (SGLT2-Is) are well known to exert beneficial effects in chronic heart failure (CHF) independent of left ventricular ejection fraction (LVEF). As inflammation plays a key role in…
View details →Whiteside SPH, Gloe LM, Biggs BK · 2026 · Journal of clinical psychology
Objectives Cognitive behavioral therapy (CBT) is the most researched treatment for childhood anxiety disorders (CADs). Improving outcomes and efficiency of CBT will require identifying and optimizing the most efficacious therapeutic…
View details →Erdoğan F, Cengiz T, Şimşek ŞA et al. · 2026 · Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
Background Pediatric femoral neck fractures are rare but carry a high risk of complications such as avascular necrosis (AVN), premature physeal closure, and coxa vara. Although stable internal fixation is essential, the optimal number of…
View details →Pandey K, Choubey B, Gupta N et al. · 2026 · Journal of neonatal-perinatal medicine
BackgroundRespiratory distress is a frequent complication in preterm infants, often requiring respiratory support. Respiratory distress syndrome (RDS), caused by surfactant deficiency in the immature lung, is the predominant etiology in…
View details →Makiev EA, Kozhevnikova TN, Pronin AV et al. · 2026 · Voprosy virusologii
Objective To evaluate how influenza infection affects the hypolipidemic effect of a novel combined drug - Prenophytol based on polyisoprenoids (sodium polyprenyl phosphate and beta-sitosterol) in mice with experimental dyslipidemia.…
View details →Mohamed FB, Middleton DM, Manmatharayan A et al. · 2026 · Spinal cord
Study design (Phantom & Human) OBJECTIVE: The purpose of this study was to optimize imaging sequences to suppress artifacts induced by metallic hardware, using phantoms implanted with spinal hardware and participants with spinal cord…
View details →Tomczyk K, Yang-Jensen KC, Lorentzen LG et al. · 2026 · Scientific reports
Prasterone (dehydroepiandrosterone, DHEA) is increasingly used in the treatment of genitourinary syndrome of menopause (GSM), although its molecular effects on vaginal tissue remain insufficiently characterized. This prospective study…
View details →Wen YC, Chu FY, Wang TH et al. · 2026 · Clinical toxicology (Philadelphia, Pa.)
Introduction Hydrogen sulfide exposure is a major cause of occupational poisoning and is frequently associated with life-threatening effects. This study aimed to investigate the patterns, poisoning severity, and predictors of severity in…
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