11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Hernigou P, Caton J · 2025 · International orthopaedics
Purpose Calcium pyrophosphate dihydrate (CPPD) deposition, often visible radiographically as chondrocalcinosis, frequently accompanies knee osteoarthritis and is usually encountered at the time of arthroplasty. Whether its presence…
View details →Grummon AH, Zeitlin AB, Lee CJY et al. · 2026 · American journal of preventive medicine
Introduction As of 2025, 9 states have adopted Universal Free School Meal programs. The success of these programs depends in part on high participation. This study tested whether a social media campaign promoting school meal participation…
View details →Sazuka T, Habu Y, Matsusaka K et al. · 2026 · International journal of clinical oncology
Background Pelvic lymph-node dissection is performed across multiple surgical specialties. However, inconsistent terminology and unclear anatomical boundaries hinder standardization. This study established a multidisciplinary team with a…
View details →Hamrick MW, Fulzele S, Isales CM et al. · 2025 · Biochimie
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is thought to play important roles in aging, oxidative stress, and cellular senescence. We have previously shown that the AhR agonist kynurenine (Kyn), a…
View details →Busse A, Müller J, Benbow ME et al. · 2025 · Journal of Applied Entomology
Understanding the dispersal ability of insects is critical for conservation efforts, as well as for preventing economic and health risks, such as the spread of bluetongue disease or African swine fever (ASF). However, knowledge of the…
View details →de Faria OAC, Kussano NR, de Faria LC et al. · 2026 · Reproduction in domestic animals = Zuchthygiene
This study aimed to evaluate whether the quality of injection and number of oocytes injected during Intrafollicular Transfer of Immature Oocytes (IFIOT) affect ovulation timing, follicle dynamics, oocyte recovery, nuclear maturation and in…
View details →Ng PH, St-Hilaire S · 2025 · Diseases of aquatic organisms
Microcystis spp. blooms in fish ponds can lead to fluctuations in water parameters, and the microcystin-LR (MC-LR) toxin they produce may pose health risks for fish, as well as consumers. Hydrogen peroxide (H2O2) treatment has been…
View details →Klaassen AD, Willigenburg NW, Musters JWQ et al. · 2026 · The Journal of bone and joint surgery. American volume
Background Hip dislocation is the most common reason for early revision after total hip arthroplasty (THA). To prevent dislocation, patients are often prescribed movement restrictions following THA; however, these restrictions can be…
View details →Xie Z, Yang C, Yin Y et al. · 2025 · Heart (British Cardiac Society)
Background Intensive blood pressure (BP) control Methods This is a post hoc analysis of the China Rural Hypertension Control Project. Mixed-effect Cox proportional regression and generalised estimating equation models were used to…
View details →Chandan Reddy S, Mao T, Gendreau J et al. · 2026 · Clinical neurology and neurosurgery
Objective Oligodendrogliomas are typically benign tumors that arise within the white matter tracts of the cerebral hemispheres. Surgical resection, radiotherapy (RT), and chemotherapy (CT) are utilized to prolong survival in patients…
View details →Davila-Piñón P, Díez-Martín AI, Nogueira-Rodríguez A et al. · 2026 · Endoscopy
Background and study aim The impact of computer-aided detection (CADe) systems remains uncertain. We evaluated whether PolyDeep, a CADe system, improves adenoma detection rate (ADR) in a colorectal cancer (CRC) screening program. Patients…
View details →de Lint L, de Vries R, van Rookhuijzen M et al. · 2026 · Appetite
Food choices are not made within a vacuum but depend upon earlier decisions, resulting in spillover effects where subsequent choices are either similar (consistency) or contrasting (balancing). Little is known about spillovers in…
View details →Pervane YD, Bağlan E · 2025 · Expert opinion on biological therapy
Objective Biologic agents have been used in colchicine-resistant familial Mediterranean fever (FMF) patients and in patients with comorbidities including juvenile idiopathic arthritis (JIA). The main aim of our study was to evaluate the…
View details →Savin Z, Ben-David R, Shem-Tov Dlugy A et al. · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Introduction Active surveillance (AS) requires regular monitoring to detect disease progression. Multiparametric magnetic resonance imaging (mpMRI) and targeted biopsies are commonly used to identify clinically significant prostate cancer…
View details →Collins SF, Soliz L, Tucker G et al. · 2025 · Science of the Total Environment
Here, we assessed patterns of microplastics (MP; particles <5 mm) and microfibers (MF; fibers <5 mm) within benthic macroinvertebrates and fishes collected from a polluted urban stream (10-km segment; n = 5 reaches; 200-m reach lengths).…
View details →Akiyama H, Sasaki Y, Tago K et al. · 2025 · Agriculture, Ecosystems and Environment.
Previous studies have reported that nitrification inhibitors are effective in reducing nitrous oxide emissions. However, no studies have reported the effectiveness of 3,4-dimethylpyrazole phosphate, and 3,4-dimethylpyrazole succinic acid…
View details →Vavricka SR, Zeitz J, Madanchi M et al. · 2025 · The American journal of gastroenterology
Introduction Retrospective data suggest association of high-altitude exposure and inflammatory bowel disease flares. Knowledge about underlying pathogenesis remains limited. Methods This prospective interventional trial evaluated the…
View details →Hammett JF, Kirwan M, Chen W · 2026 · Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors
Objective Intimate partner violence (IPV) is a major public health concern. Heavy episodic drinking (HED; i.e., drinking 5+ drinks for men or 4+ drinks for women in a 2-hr period) is a contributing cause of IPV, yet HED does not elicit IPV…
View details →Savran F, Bayram F, Küçük F · 2026 · The Journal of craniofacial surgery
Objective This study aimed to evaluate the effects of intravenous dexamethasone and tranexamic acid (TXA), used alone and in combination, on perioperative bleeding and postoperative edema and ecchymosis in rhinoplasty. Methods In this…
View details →Lipps KM, Samuel AM, Patel D et al. · 2025 · Journal for healthcare quality : official publication of the National Association for Healthcare Quality
Background Hypertension (HTN) is common in the inpatient setting, with many patients receiving as-needed (PRN) antihypertensive medications (anti-HTN) despite lack of benefit and risk of adverse events. We aimed to decrease PRN anti-HTN…
View details →Kato K, Honda Y, Kamatani T et al. · 2026 · Arthritis & rheumatology (Hoboken, N.J.)
Objective Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory disease caused by gain-of-function mutations in NLRP3. Although somatic NLRP3 mosaicism is increasingly recognized, it remains unclear how variant allele…
View details →Demeckova V, Demcakova V, Sedlakova-Kadukova J · 2025 · IEEE transactions on nanobioscience
Silver nanoparticles (AgNPs) are widely used for their antimicrobial properties but pose risks like environmental contamination and potential harm to human health. Nanoparticles' small size facilitates translocation within the body, often…
View details →Shaik NF, Denison L, Venezia GMA et al. · 2026 · Journal of hospital medicine
Background Hospitalized patients often experience poor sleep, which is associated with worse health outcomes, increased rates of delirium, and readmissions. Objective To improve overnight sleep for clinically stable general neurology…
View details →Zhang J, Wu Q, Chi D et al. · 2025 · Soil & tillage research
Phosphorus-loaded iron-modified biochar (Fe-BP) can be used as farmlands' slow-release phosphorus (P) fertilizer. This study aimed to explore the effects of Fe-BP on soil P composition, phosphatase activity, peanut P accumulation, and P…
View details →Lukyanov AN, Vargin PN, Yushkov VA · 2025 · Atmospheric research
The eruption of the underwater volcano Hunga Tonga – Hunga Ha'apai (20.54° S, 178.3° W) on January 15, 2022, resulted in the first significant increase in the stratospheric water vapor content in the entire satellite observation era. This…
View details →Ackermann DM, Medcalf E, Bracken K et al. · 2026 · Journal of clinical epidemiology
Objectives Digital reminders are widely used in clinical trials, but their design is rarely evidence-based. We evaluated the effectiveness of two types of digital reminders for trial task completion. Study design and setting This…
View details →Jones PAT, Brockwell E, Hassan A et al. · 2025 · British journal of sports medicine
Objective Recreational and elite athletes report avoiding breastfeeding when returning to physical activity following childbirth due to a perceived increased risk of injury; yet, there are no empirical data to support this relationship. We…
View details →Sadowska-Klasa A, Bełdzińska-Gądek K, Klein-Awerjanow K et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Cytomegalovirus (CMV) pneumonia is a serious complication in immunocompromised patients, but its role in non-transplant populations remains unclear. Methods We analyzed CMV DNA in bronchoalveolar lavage (BAL) samples from 100…
View details →Murray RL, Baldwin D, Brain K et al. · 2026 · Thorax
Introduction Lung cancer screening (LCS) with low-dose CT offers a teachable moment for smoking cessation (SC), but the optimal way to implement SC within LCS is unclear. The Yorkshire Enhanced Stop Smoking (YESS) study assessed the…
View details →Garrido-Bautista J, Ortega Z, Pérez-Jiménez A et al. · 2025 · Ecological and evolutionary physiology
AbstractClutch size variation may be adaptive in bird populations if parents lay a clutch size that maximizes offspring recruitment. Brood size manipulation experiments allow for testing the optimization of clutch size by studying the…
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