11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Brodoline I, Anselmucci F, Sadeghi A et al. · 2026 · Bioinspiration & biomimetics
Earthworm-like robots represent a promising alternative to conventional soil investigation tools currently used in geotechnics. Their limited invasiveness and ability to navigate in three-dimensions underground are highly desirable…
View details →Erdem S, Hussain T, Erdem O et al. · 2026 · Journal of the American Heart Association
Background Sarcopenia is prevalent in patients with Fontan circulation and may contribute to functional decline and adverse outcomes. It is commonly assessed using the cross-sectional area of the psoas muscle (PMA), although volumetric…
View details →Halperin JJ, Granger D · 2026 · BMC neurology
Background CSF immunoglobulin (IgG) often informs diagnosis in CNS inflammatory disease- qualitatively (oligoclonal bands; OCBs), or quantitatively (CSF: serum IgG: albumin, e.g. IgG index). Most US laboratories estimate excess CSF IgG…
View details →Bretzman J, Andrews J, Ge S et al. · 2026 · Journal of vascular and interventional radiology : JVIR
Purpose To determine the patency of portal vein stents in patients with pancreatic cancer, identify risk factors for stent occlusion, and determine whether anticoagulation improves stent patency. Materials and methods Patients with…
View details →Corianò M, Pradegan N, Putortì F et al. · 2026 · Journal of cardiovascular development and disease
Pulmonary hypertension (PH) is associated with adverse outcomes after heart transplantation (HT). In 2022, the European Society of Cardiology introduced lower thresholds for pulmonary vascular resistance (PVR) to distinguish isolated…
View details →Lysdahlgaard S, Jensen J, Pedersen MRV et al. · 2026 · Radiography (London, England : 1995)
Introduction High-quality radiographic positioning is essential for accurate diagnosis in knee imaging. Although artificial intelligence (AI) can assess image quality with high accuracy, its influence on radiographers' clinical…
View details →Watanabe A, Furukawa M, Hiruta R et al. · 2026 · Neurologia medico-chirurgica
Tractography is a technique for visualizing the trajectories of white matter pathways. The most widely used model, the diffusion tensor imaging, assumes a single fiber orientation within each voxel. In contrast, the constrained spherical…
View details →Guo ZM, Cui F, Zhang Y et al. · 2026 · BMC anesthesiology
Background Complex spinal surgery is associated with significant trauma and pain. Herein we tested the hypothesis that increasing the dose of esketamine, as a supplement to patient-controlled analgesia, might improve pain relief after…
View details →Rodak O, Alkali IM, Peris-Diaz MD et al. · 2026 · Reproduction in domestic animals = Zuchthygiene
Ovarian tissue vitrification holds great promise as a preservation technique for endangered wild felids; however, the development of an optimal protocol remains desired. One potential factor affecting success is the equilibration…
View details →Gillessen S, Gobat K, Cathomas R et al. · 2026 · European urology oncology
Background and objective The aim of our study is to determine whether the addition of metformin to enzalutamide can improve the outcomes of men with metastatic castration-resistant prostate cancer (mCRPC). Methods From 2016 to 2021,…
View details →Lizama E, Carcamo-Herrera B, López G et al. · 2026 · Psychoneuroendocrinology
Performance in precision sports such as golf depends on the athlete's ability to regulate psychophysiological responses under competitive pressure. Heart rate variability (HRV), cortisol, and DHEA provide complementary indices of autonomic…
View details →Ho K, Adjei-Afriyie O, Carmona-Martinez R et al. · 2026 · Brain communications
Congenital myasthenic syndromes (CMS) are a group of rare disorders characterized by fatigable muscle weakness and caused by impaired neuromuscular junction (NMJ) function. CMS symptoms are highly variable, but it can be detrimental and…
View details →Morales AA, Camarena V, Peart L et al. · 2026 · Scientific reports
Geleophysic dysplasia (GD) is a rare genetic disorder characterized by short stature, joint contractures, and cardiopulmonary complications, with early mortality, and linked to mutations in ADAMTSL2 (GD1), FBN1 (GD2), or LTBP3 (GD3) genes.…
View details →Halko ML, Halonen J, Laukkanen M et al. · 2026 · Cognition & emotion
Political and economic challenges, amplified by social media algorithms, are increasingly polarising how people receive and evaluate information. This study examines how political views and immediate emotional reactions shape the perceived…
View details →Araga Y, Nakamura Y, Sugita C et al. · 2026 · Rinsho shinkeigaku = Clinical neurology
The patient was a 30-year-old man who was admitted to our department 2 months after the onset of anterograde amnesia. Cognitive function tests indicated memory impairment only. MRI FLAIR images of the head showed a high signal in the…
View details →Pham TN, Chamseddine I, Lebhertz D et al. · 2026 · Physics in medicine and biology
Introduction. Radiation-induced optic neuropathy (RION) is a rare but functionally-disabling complication of radiotherapy for brain and head/neck tumors. Even with modern proton therapy and adherence to dose constraints, about 6% of…
View details →Shi L, Li Y, Li C et al. · 2026 · International journal of clinical oncology
Background Comparative evidence for neoadjuvant chemoimmunotherapy (NCIT) versus neoadjuvant immunotherapy combined with chemoradiotherapy (NICRT) in locally advanced esophageal squamous cell carcinoma (ESCC) is limited. We compared…
View details →Hatipoğlu Ö, Başar Ö, Mağat G et al. · 2026 · Scientific reports
Accurate detection of overhanging dental restorations on bitewing radiographs is clinically important but remains challenging due to subtle marginal discrepancies. This study aimed to develop and compare deep learning-based instance…
View details →Packet B, Van Severen R, Cattani L et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objectives To study the association between the subpubic arch angle and area, the latter a novel estimator of maternal pelvic outlet dimensions, and postpartum anal incontinence. Methods Convenience sample from a prospective observational…
View details →Aglen T, Matre KH, Selles RW et al. · 2026 · Journal of hand therapy : official journal of the American Society of Hand Therapists
Background Collagenase treatment can improve finger extension and hand function in patients with Dupuytren's disease. The role of hand therapy in enhancing or prolonging these effects remains unclear. Purpose The primary aim was to examine…
View details →Steen JP, Jaiswal KS, Dilipkumar J et al. · 2026 · The journal of pain
The measurement performance of the Short-Form Brief Pain Inventory (BPI-SF) across IASP-recognized pain mechanisms remains unclear. We evaluated the reliability and structural validity of BPI-SF across clinician-assigned predominant…
View details →Ghofranian A, Baird M, Reckhow J et al. · 2026 · Minerva obstetrics and gynecology
Background Luteal phase E2 priming is commonly used in patients with DOR to 30 synchronize follicular development before controlled ovarian hyperstimulation (COH). Some protocols 31 incorporate a GnRH antagonist during the luteal phase to…
View details →Kongkhuntian P, Aunmeungtong W, Khongkhunthian P · 2026 · Clinical implant dentistry and related research
Objective This study aimed to compare the effect of PTFE tape wrapping and PTFE-coated titanium alloy screws on the removal torque after cyclic loading and on preload values under repetitive tightening. Methods A total of 60 titanium…
View details →Tournu E, Tourdot-Maréchal R, Coelho C · 2026 · International journal of food microbiology
Phytosanitary and copper treatments in viticulture are essential to protect vines against biotic and abiotic stresses. However, residues from these treatments can persist in grape musts and wines, potentially raising risks to consumer…
View details →McClure Z, Fuller-Tyszkiewicz M, Messer M et al. · 2026 · The International journal of eating disorders
Objective Although a range of evidence-based treatments for eating disorders exist, treatment response varies substantially. The ability to match individuals to a treatment which they are most likely to benefit from may help improve…
View details →Khatri D, Poudel S, Pun Magar L et al. · 2026 · Frontiers in plant science
Soybean meal quality for monogastric animals is limited by low sulfur-containing amino acids, especially methionine and cysteine, while oil oxidative stability is restricted by the high polyunsaturated fatty acid content. This two-year…
View details →Wall A, Fisher JA, Watkinson EK et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Background Early warning scores like the National Early Warning Score 2 (NEWS2) identify patient deterioration but do not incorporate clinician-intuitive assessment. Previous research suggests facial expressions can be critical indicators…
View details →Larsen LJ, Dornbusch MR, Hines-Snider C et al. · 2026 · Plant disease
Seed rot and damping-off of alfalfa ( Medicago sativa L.) is caused by a soilborne disease complex resulting in thin initial stands of plants with continuing damage during wet soil conditions decreasing forage yields and winter survival.…
View details →Giese H, Gaissmaier W, Kuss O et al. · 2026 · Medical decision making : an international journal of the Society for Medical Decision Making
BackgroundTime-to-event outcomes from randomized controlled trials (RCTs) are often communicated without clearly conveying how treatment effects evolve over time. This can limit clinicians' ability to interpret results and support patient…
View details →Müller D, Gillani A, Hirschmann MT et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Purpose Accurate risk adjustment in total knee arthroplasty (TKA) is essential for outcome prediction and quality assessment. Most existing prediction models rely solely on patient demographics and comorbidities and do not account for…
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