Enzalutamide Plus Metformin Versus Enzalutamide Alone in Metastatic Castration-resistant Prostate Cancer: A Randomized Phase 2 Trial (SAKK 08/14).
Gillessen S; Gobat K; Cathomas R; Fischer N; Pereira Mestre R; Hermanns T; Rothschild SI; Mach N · 2026 · European urology oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background and objective The aim of our study is to determine whether the addition of metformin to enzalutamide can improve the outcomes of men with metastatic castration-resistant prostate cancer (mCRPC). Methods From 2016 to 2021,…
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Metadata source: Europe PMC · DOI 10.1016/j.euo.2026.03.001