11,319 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Wamsley EJ, Barron J, Livingston WH · 2026 · Journal of cognitive neuroscience
Memory is consolidated during "offline" states of reduced attention to the external stimulus environment, including sleep and resting wakefulness. While consolidation is usually studied on a timescale of hours to days, accumulating…
View details →Piazza FRG, Schuch JB, Ferreira DNSDS et al. · 2025 · Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
Objective N-acetylcysteine (NAC) is a medication known for its hepatoprotective properties and potential to reduce cravings and psychoactive substance use. Vitamin D is metabolized in the liver, and individuals with alcohol abuse often…
View details →Chen PA, Hsueh YC, Lin YC et al. · 2026 · The Journal of arthroplasty
Background Whether the addition of magnesium sulfate (MgSO 4 ) to intra-articular analgesic cocktails improves early pain after total knee arthroplasty (TKA) remains uncertain. Methods This prospective, double-blind, within-patient…
View details →Leak M, Giambini H, Cheever K et al. · 2026 · Journal of sport rehabilitation
Context Thoracic mobility is integral to respiratory function and mobility of the neck, shoulder, and spine. The efficacy of thoracic mobility exercises in enhancing respiratory function and spinal range of motion (ROM) is well documented…
View details →Mayer J, Al-Sheikhli J, Wang X et al. · 2026 · JACC. Clinical electrophysiology
Background Functional extra-stimulus (ES) substrate mapping has been shown to reduce the recurrence of ventricular tachycardia (VT) compared with intrinsic rhythm mapping. However, there is no standardized approach to functional ES…
View details →Mattila N, Meinberg M, Juppo A et al. · 2026 · Scandinavian journal of gastroenterology
Objective To assess whether a gargled articaine solution makes gastroscopy more tolerable for the patient. Background Gastroscopy is an unpleasant experience for most people. A drug that is easy to use, has a fast onset, enables quick…
View details →Hoberstorfer T, Nopp S, Steiner D et al. · 2026 · Journal of thrombosis and haemostasis : JTH
Growth differentiation factor-15 (GDF-15) has been proposed as a bleeding biomarker. To evaluate the predictive value of GDF-15 for clinically relevant bleeding (CRB, major bleeding and clinically relevant non-major bleeding [CRNMB])…
View details →Asmundo L, Pansini V, Monti CB et al. · 2026 · Abdominal radiology (New York)
To evaluate the diagnostic performance of hepatic extracellular volume (ECV) fraction derived from delayed single-energy CT for identifying graft rejection in liver transplant recipients and its added value over clinical parameters. This…
View details →Kikkawa K, Takeuchi M, Sakaguchi D et al. · 2026 · Journal of anesthesia
Purpose Monitored anesthesia care (MAC) is increasingly used for various procedures, but sedation-related upper airway obstruction may lead to hypoxemia or conversion to general anesthesia. This study evaluated whether preoperative tongue…
View details →Jin Z, Ueda K, Higo F et al. · 2026 · Anesthesia and analgesia
Background Prehabilitation during unavoidable surgical delay after an acute femoral neck fracture may mitigate rapid functional decline but is often limited by movement-evoked pain. The pericapsular nerve group (PENG) block is a…
View details →Navarro LP, Combes X, Galinski M et al. · 2026 · BMC emergency medicine
Introduction We aimed to assess the relationship between arterial partial pressure of carbon dioxide (PaCO 2 ) and end-tidal carbon dioxide (EtCO 2 ) according to three prehospital hemodynamic status and to evaluate whether…
View details →Jorritsma R, Bijkerk HJC, Martina R et al. · 2026 · Irish veterinary journal
In September 2023, the official national reference laboratory confirmed the presence of BTV serotype 3 in The Netherlands. In the following weeks, it appeared that the infection caused very severe clinical signs in sheep, but it was…
View details →Burtnett SL, Bomberger RA, Harvatine KJ · 2026 · Journal of dairy science
Oleic acid has a lower risk for biohydrogenation-induced milk fat depression (MFD) than linoleic acid and can act as an emulsifier to aid fatty acid (FA) digestion in the small intestine. Our objective was to evaluate the effect of high…
View details →Alachkar MN, Schlegl J, Bannehr M et al. · 2026 · Journal of cardiovascular development and disease
Background The TRI-SCORE was developed to predict mortality after tricuspid valve surgery and has demonstrated prognostic value in patients undergoing transcatheter tricuspid valve interventions (TTVI). Right ventricular-pulmonary arterial…
View details →Ptaszek B, Kurek O, Podsiadło S · 2026 · Lymphatic research and biology
Purpose In times when health and physical activity are gaining in value, the search for effective methods to support fitness and improve quality of life is becoming a priority. One of the therapies that is gaining increasing popularity is…
View details →Eves R, Deppe M, Kandler C et al. · 2026 · Journal of child psychology and psychiatry, and allied disciplines
Background Past studies indicate significant associations between birth anthropometrics, such as relative birthweight or head circumference, and later cognitive performance. Using twin data, we investigated whether these associations are…
View details →Toillon I, Badoud I, Ferrari S et al. · 2026 · Bone
Type 1 diabetes is associated with increased fracture risk, yet the respective contributions of insulin deficiency and replacement to skeletal fragility remain poorly understood. Using insulin-deficient male Akita mice, we characterized…
View details →Kabuga E, Nandi D, Burrell S et al. · 2026 · The Journal of the Acoustical Society of America
Individual animal identification is essential for wildlife conservation and management, aiding in estimating abundance and related parameters. The feasibility of identifying individual field crickets (Plebeiogryllus guttiventris) from…
View details →Garitaonaindia Y, Witteveen S, Dionisio E et al. · 2026 · Journal of the National Cancer Institute
Background Pathological complete response (pCR) and circulating tumor DNA (ctDNA) clearance are increasingly used as intermediate endpoints in neoadjuvant and perioperative immunotherapy (IO) trials. However, whether complete pathological…
View details →Alsharif P, Strauss A, Ng W et al. · 2026 · Family medicine
Background and objectives Point-of-care ultrasound (POCUS) is increasingly used in inpatient settings to evaluate patients. Common applications include cardiac, lung, hemodynamic assessment, and venous access. Teaching and achieving…
View details →Ghorooneh Z, Mohammadzadeh A, Farhat AS et al. · 2026 · BMC pediatrics
BACKGROUND: Whether small for gestational age adds prognostic information after NICU admission physiology is known remains uncertain in preterm infants. This distinction is clinically important because SGA is an anthropometric birth-size…
View details →Turner D, Mehdizadeh-Shrifi A, Faateh M et al. · 2026 · World journal for pediatric & congenital heart surgery
BackgroundWe sought to characterize the epidemiology, treatment patterns, and outcomes of neonatal Ebstein anomaly using a national database.MethodsIn this descriptive analysis, the pediatric health information system (PHIS) database was…
View details →Brodoline I, Anselmucci F, Sadeghi A et al. · 2026 · Bioinspiration & biomimetics
Earthworm-like robots represent a promising alternative to conventional soil investigation tools currently used in geotechnics. Their limited invasiveness and ability to navigate in three-dimensions underground are highly desirable…
View details →Erdem S, Hussain T, Erdem O et al. · 2026 · Journal of the American Heart Association
Background Sarcopenia is prevalent in patients with Fontan circulation and may contribute to functional decline and adverse outcomes. It is commonly assessed using the cross-sectional area of the psoas muscle (PMA), although volumetric…
View details →Halperin JJ, Granger D · 2026 · BMC neurology
Background CSF immunoglobulin (IgG) often informs diagnosis in CNS inflammatory disease- qualitatively (oligoclonal bands; OCBs), or quantitatively (CSF: serum IgG: albumin, e.g. IgG index). Most US laboratories estimate excess CSF IgG…
View details →Bretzman J, Andrews J, Ge S et al. · 2026 · Journal of vascular and interventional radiology : JVIR
Purpose To determine the patency of portal vein stents in patients with pancreatic cancer, identify risk factors for stent occlusion, and determine whether anticoagulation improves stent patency. Materials and methods Patients with…
View details →Corianò M, Pradegan N, Putortì F et al. · 2026 · Journal of cardiovascular development and disease
Pulmonary hypertension (PH) is associated with adverse outcomes after heart transplantation (HT). In 2022, the European Society of Cardiology introduced lower thresholds for pulmonary vascular resistance (PVR) to distinguish isolated…
View details →Lysdahlgaard S, Jensen J, Pedersen MRV et al. · 2026 · Radiography (London, England : 1995)
Introduction High-quality radiographic positioning is essential for accurate diagnosis in knee imaging. Although artificial intelligence (AI) can assess image quality with high accuracy, its influence on radiographers' clinical…
View details →Watanabe A, Furukawa M, Hiruta R et al. · 2026 · Neurologia medico-chirurgica
Tractography is a technique for visualizing the trajectories of white matter pathways. The most widely used model, the diffusion tensor imaging, assumes a single fiber orientation within each voxel. In contrast, the constrained spherical…
View details →Guo ZM, Cui F, Zhang Y et al. · 2026 · BMC anesthesiology
Background Complex spinal surgery is associated with significant trauma and pain. Herein we tested the hypothesis that increasing the dose of esketamine, as a supplement to patient-controlled analgesia, might improve pain relief after…
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