11,317 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Legler M, Heenemann K · 2025 · Veterinary sciences
The common swift is the most observed swift species in Germany. During the summer months in urban areas, juvenile swifts in need of help are frequently cared for in wild bird rescue centers. Providing adequate housing and veterinary…
View details →Zosim V, Mullie C, Peltier F et al. · 2025 · Molecular biology reports
Background Antimicrobial resistance (AMR) in Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. (ESKAPE pathogens), notably in carbapenem-resistant…
View details →Atobatele S, Mpimbaza A, Ngufor C et al. · 2025 · Malaria journal
Background Malaria rapid diagnostic tests (RDTs) have improved case management and surveillance across sub-Saharan Africa by reducing presumptive treatment and enhancing diagnostic specificity. However, healthcare workers' (HCWs) concerns…
View details →Ebner R, Braach J, Rübenthaler J et al. · 2025 · Journal of nuclear medicine : official publication, Society of Nuclear Medicine
The aim of this retrospective study was to evaluate the correlation between findings from somatostatin receptor (SSTR) PET/CT and histopathology in patients with suspected intracranial meningiomas. Methods: We conducted a retrospective…
View details →Horn EJ, Menefee B, Schotthoefer AM et al. · 2026 · Journal of clinical microbiology
Current laboratory testing for Lyme disease (LD) relies on serology. We evaluated the performance of standard two-tiered testing (STTT) and modified two-tiered testing (MTTT) algorithms using samples obtained from well-characterized…
View details →Baumgarten J, Stephan E, Ohlwärther TEN et al. · 2026 · Forensic science, medicine, and pathology
Estimation of the postmortem interval (PMI) of found bones is an important and challenging part of forensic osteology assessments. This study examined human long bones that had been taken from cemeteries and hoarded by a "bone collector".…
View details →Sheybani L · 2026 · The European journal of neuroscience
A recent study by Hausdorf et al. reported that combining closed-loop acoustic stimulation with transcranial direct current stimulation during sleep does not improve memory consolidation. This contrasts with past studies that reported a…
View details →Pruss A, Skierska A, Kwiatkowski P et al. · 2025 · PloS one
Klebsiella pneumoniae is a typical opportunistic pathogen that exhibits multiple virulence factors and antibiotic resistance conditioning mechanisms. Carbapenemases are enzymes that help bacteria to exhibit the strongest resistance against…
View details →Bolterstein E, Mungre S, Nuss K et al. · 2025 · microPublication biology
WRNexo and Blm , Drosophila orthologs of human WRN and BLM RecQ helicases, play crucial roles in DNA replication and repair. Using a Course-based Undergraduate Research Experience (CURE) in an introductory Biology course, we investigated…
View details →Uedo N, Gotoda T, Takizawa K et al. · 2026 · The American journal of gastroenterology
Introduction The recommendation to discontinue low-dose aspirin (LDA) during the periprocedural period of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) remains controversial in patients at low thrombotic risk. If…
View details →Zabir MOH, Habib MA, Monalisa et al. · 2026 · IJID regions
Objectives Acute respiratory infections (ARIs) such as influenza-like illness (ILI) and severe acute respiratory infection (SARI) are leading causes of morbidity among children aged under 5 years (under-5) in Bangladesh. In Cox's Bazar,…
View details →Fróes LAR Júnior, Sotto MN, Avancini J et al. · 2026 · Anais brasileiros de dermatologia
Early diagnosis of leprosy remains primarily clinical, based on recognition of skin lesions with altered sensation and peripheral nerve involvement. However, complementary tests play crucial roles in confirming uncertain cases, guiding…
View details →Zhao G, Jiao Z, Dai P et al. · 2023 · Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
Objective To explore the cause for a twin pregnancy with false negative result for 22q11.2 deletion syndrome by expanded non-invasive prenatal testing (NIPT-plus). Methods A pregnant woman with twin pregnancy through in-vitro fertilization…
View details →Maegele M, Breidenbach L, Kaufmann J et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Introduction Mild traumatic brain injuries (mTBI) affect millions of people worldwide every year as one of the most common clinical presentations in the emergency department. Diagnosis is mainly based on clinical criteria and computed…
View details →Wagenhofer V, Mihaljević I, Kralj T et al. · 2024 · Acta clinica Croatica
The aim was to determine the diagnostic value of stimulated serum thyroglobulin (sTg) for the follow-up of patients with differentiated thyroid cancer (DTC) and to evaluate whether repeated sTg measurement provides additional clinical…
View details →Wittenborn J, Cuma C, Kennes LN et al. · 2026 · Diagnostics (Basel, Switzerland)
Objective: The aim of this study was to evaluate the positive predictive value of endocervical curettage (ECC) during colposcopic examination in a dysplasia unit since the implementation of the new cervical cancer screening program in…
View details →Mu Y, Jing Y, Liu X et al. · 2026 · International journal of women's health
Background Non-invasive prenatal testing (NIPT) is widely adopted for its high sensitivity in detecting chromosomal abnormalities, but its accuracy for placental and fetal mosaicism is limited due to reliance on placental DNA, leading to…
View details →Iamchaimongkol A, Leeareekun K, Chira-Adisai W et al. · 2026 · Journal of rehabilitation medicine
Objective To assess the correlation between controlled-pressure provocative test duration and electrodiagnostic severity in carpal tunnel syndrome. Design Cross-sectional correlational study. Patients Patients with clinical symptoms…
View details →Nanni AG, Urso D, Caccamo M et al. · 2024 · Journal of Alzheimer's disease reports
This report presents a challenging case of Creutzfeldt-Jakob Disease (CJD), a rare and rapidly progressing neurological disorder. The patient exhibited diverse and progressive neuro-psychiatric symptoms, including memory impairment,…
View details →Kim JH, Shin JY, Park SY et al. · 2024 · Scientific reports
The somatic BRCA1 or BRCA2 Pathogenic Variant (PV)/Likely PV (LPV) from Next Generation Sequencing (NGS) is the most important biomarker for PARP inhibitor use and maintenance-targeted therapies. A discrepancy in the detection rates of…
View details →Heyman Y, Röjlar H, Hawranek C et al. · 2026 · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
PURPOSE: As genetic testing becomes increasingly integrated into routine care, understanding its impact on psychological well-being and health-related quality of life (HRQoL) is essential. This study assessed HRQoL, anxiety and cancer…
View details →Vega-Gonzalez J, Toro JAC, García EL et al. · 2025 · Genes, chromosomes & cancer
According to the 5th edition of the WHO Classification of Soft Tissue and Bone Tumors, the diagnosis of synovial sarcoma relies on morphology, immunohistochemistry, and the detection of a specific fusion involving the SS18 gene with a…
View details →Taechikantaphat M, Kongchareon A, Julapanthong P et al. · 2026 · Veterinary and animal science
This prospective, randomized clinical trial compared the therapeutic efficacy and rate of platelet recovery of doxycycline 10 mg/kg once daily (SID) (Group A, n=17) versus 5 mg/kg twice daily (BID) (Group B, n=12) in 29 dogs naturally…
View details →Pimentel V, Becker J · 2025 · Arquivos de neuro-psiquiatria
Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune demyelinating disease characterized by a high risk of relapse and disability. In cases positive for aquaporin 4-immunoglobulin G (AQP4-IgG), long-term immunosuppression…
View details →Mazzotta E, Natale A, Bellinati L et al. · 2025 · Animals : an open access journal from MDPI
Equid milk (donkey or mare) has traditionally been consumed raw or fermented due to its distinctive chemical composition, which closely resembles human milk, and its nutritional benefits. Nowadays, interest in it is increasing, despite…
View details →Bai M, Li Y, Gao Q et al. · 2025 · Virology journal
Purpose Present study aimed to compare the boiling and magnetic bead nucleic acid extraction method for HPV genotypes detection. Methods By mixing hemoglobin with HPV positive quality control products, the anti-interference ability of two…
View details →Limaye AP, Crespo M, Kamar N et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background QuantiFERON-cytomegalovirus (QFT-CMV) is a standardized assay for the evaluation of cytomegalovirus-specific cell-mediated immunity (CMV-CMI). Objectives The purpose of this study was to assess the evolution of CMV-CMI…
View details →Wang X, Fan Z, Huo L et al. · 2025 · Breast care (Basel, Switzerland)
Background In sentinel node biopsy (SNB) procedure for breast cancer patient, whether the abnormal node was excised is uncertain. The impact of abnormal node on the accuracy of SNB results is unknown. Methods In this prospective study,…
View details →Russo F, Chatterjee D, DeMaria N et al. · 2024 · Journal of community genetics
DNA-based population screening for adult-onset diseases holds promise for advancing personalized medicine and improving public health. Yet as most individuals pursuing such screening receive negative results, the return of results process…
View details →Roman TS, Gray SM, Sneddon TP et al. · 2026 · HGG advances
The impact of clinical exome and genome sequencing (ES/GS) depends on the clinical setting. In the sequencing arm of a multifactor randomized clinical trial to evaluate broadening access, we assessed the diagnostic and inconclusive…
View details →