11,317 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Sato K, Inoue K, Yamaguchi T et al. · 2025 · JAMA network open
Importance Excess salt intake is a major modifiable risk factor for hypertension and cardiovascular disease. Personalized interventions using genetic information and digital tools, such as smartphone applications, may enhance sodium…
View details →Liu P, Zeng Q · 2025 · Journal of multidisciplinary healthcare
Background The causal relationship between HIV infection and insulin resistance, as well as diabetes mellitus, remains uncertain. This study explores these associations using genome-wide association study data and Mendelian randomization…
View details →Shaaban M, Ryan JT, Adediran E et al. · 2026 · F&S reports
Objective To study whether incident endometriosis diagnosis, staging, and typology are associated with concurrent elevated serum inflammatory markers interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF- α ).…
View details →Zebarjadi N, Kluge A, Adler E et al. · 2024 · eNeuro
The study of ideological asymmetries in empathy has consistently yielded inconclusive findings. Yet, until recently these inconsistencies relied exclusively on self-reports, which are known to be prone to biases and inaccuracies when…
View details →Anettová L, Šipková A, Cibulka P et al. · 2025 · Parasitology research
This study summarizes the findings of a comprehensive field investigation into the presence of Angiostrongylus cantonensis, a zoonotic nematode responsible for meningitis, in selected regions of the eastern Mediterranean. Samples were…
View details →Vengurlekar IN, Thudi KR · 2025 · Psychological reports
Video gaming has become a popular method of entertainment for college students. Previous work indicates mixed results regarding the link between video gaming and mental health outcomes. However, little research has addressed how different…
View details →Chatlaong MA, Stanford DM, Miller WM et al. · 2024 · Clinical hemorheology and microcirculation
Background Post-occlusive reactive hyperemia (PORH) typically requires caffeine abstinence. For habitual users, it is unknown if abstinence affects PORH. Objective Compare PORH after habitual users consume or abstain from caffeine. Methods…
View details →Gupta A, Dashti HS · 2025 · Current sleep medicine reports
Purpose of review Daytime napping, a brief sleep episode during the day, has mixed health effects. This review explores the relationship between daytime napping frequency and health outcomes by synthesizing results from published Mendelian…
View details →Ashy C, Few WE, Rivas GA et al. · 2026 · HCA healthcare journal of medicine
Introduction Concerns are rising regarding the quality, validity, and reliability of clinical research findings in medical literature. This investigation sought to identify the most cited orthopedic clinical studies and assess the…
View details →López-Padilla MF, Seoane-Miraz D, Guiñón-Fort D et al. · 2026 · Antioxidants (Basel, Switzerland)
Polyphenols represent the largest and most diverse class of dietary antioxidants. Epidemiological evidence linking specific (poly)phenol classes, such as flavonoids and lignans, to breast cancer (BC) risk remains limited and largely…
View details →Zhang X, Machlin L, McLaughlin K et al. · 2025 · Developmental psychology
This study tests Frankenhuis and Panchanathan's (2011) evolutionary commitment hypothesis by examining individual differences in susceptibility to the effects of parenting during early and late childhood. Drawing from the Future of…
View details →O'Connell SR, Wilson GE, Berkowitz DH et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Groove is the pleasurable urge to move to the beat of music, a universally experienced human phenomenon. Because listeners are often inspired to move to music with groove, we asked whether high-groove music would promote greater motor…
View details →Colbeth HL, Riddell CA, Thomas M et al. · 2024 · Journal of epidemiology and community health
Background Structural racism's influence on workforce policies and practices presents possible upstream targets for assessing and reducing racial health disparities. This study is the first to examine workforce racial diversity in…
View details →Miller AL, Zhao Y · 2023 · Physical review letters
Over 10 years ago, Fermi observed an excess of GeV gamma rays from the Galactic Center whose origin is still under debate. One explanation for this excess involves annihilating dark matter, another requires an unresolved population of…
View details →King M, Bruinsma S, Ivry RB · 2024 · Neurobiology of language (Cambridge, Mass.)
Cerebellar involvement in language processing has received considerable attention in the neuroimaging and neuropsychology literatures. Building off the motor control literature, one account of this involvement centers on the idea of…
View details →Obara-Gołębiowska M · 2026 · Eating and weight disorders : EWD
Purpose To identify person-centered psychological profiles of eating-related risk based on early maladaptive schemas (EMS), emotion regulation difficulties, and eating behaviors, and to examine their external validation using…
View details →Bjørkheim SB, Hystad SW, Sætrevik B · 2026 · PeerJ
The way people perceive health risks is often assumed to influence how they adopt precautionary measures. However, people's assessment of a given phenomenon's risk may vary over time, and the relationship between perceived risk and…
View details →Kracht CL, Falkenhain K, Flanagan EW et al. · 2026 · JMIR mental health
Background Household chaos is an emerging risk factor for childhood obesity development, especially in families with lower socioeconomic status (SES). It is unclear if changes in household chaos, especially in pregnancy, may mediate the…
View details →Neelam P, Sowndarya K, Anupama H et al. · 2025 · Advanced biomedical research
Background Homocysteine (Hcy) and dyslipidemia are established risk parameters of atherosclerosis. Considerable research has been conducted using ratios of lymphocytes to other cellular components of the peripheral white blood cell count…
View details →Serimaa O, Keltikangas-Järvinen L, Lyytikäinen LP et al. · 2025 · Psychological medicine
Background Previous evidence has reported associations of a polygenic risk score for schizophrenia (PRS SCZ ) with negative developmental outcomes, such as psychiatric symptoms, adverse health behaviors, and reduced everyday functioning.…
View details →Cheema S, Augustin C, Göttlich M et al. · 2024 · eNeuro
The growing field of social neuroscience is reliant on the development of robust, ecologically valid paradigms for simulating social interaction and measuring social cognition in highly controlled laboratory settings. Perspective taking is…
View details →Alshehri FS, Alshehri AS, Alhejali AE et al. · 2025 · Journal of orthodontic science
Theoretical and anatomical pathways suggest a connection between the stomatognathic and visual systems. However, the evidence for associations between dental occlusion, temporomandibular disorders (TMD), and visual function is fragmented…
View details →Javaheri S, Javaheri S, Gozal D et al. · 2024 · Journal of the American College of Cardiology
Many studies have shown an association of obstructive sleep apnea (OSA) with incident cardiovascular diseases, particularly when comorbid with insomnia, excessive sleepiness, obesity hypoventilation syndrome, and chronic obstructive…
View details →Lazar A, Rougier M, De Houwer J et al. · 2026 · International review of social psychology
Prior research revealed a correlation between individual differences in neuroticism (specifically, the component of trait anxiety) and evaluative conditioning (i.e., changes in attitude due to stimulus pairings). In two studies ( N = 274…
View details →Pelzer M, Werthmann J, Svaldi J et al. · 2026 · Eating and weight disorders : EWD
Purpose Body image disturbances (BID) are central to anorexia nervosa (AN), influencing its development, maintenance and relapse. While mirror exposure (ME) has been shown to reduce BID in adults, research in adolescents is limited. This…
View details →Simmons LA, Phipps JE, Castro-Alvarez S et al. · 2026 · BMC pregnancy and childbirth
Background Rising rates of overweight and obesity globally have led to an increasing number of women who enter pregnancy with excess weight, posing significant health risks to mothers and infants. Mobile health interventions, such as…
View details →Delgado CA, Poletto E, Vera LNP et al. · 2024 · Cell biochemistry and function
Mucopolysaccharidosis type II (MPS II) is an inborn error of the metabolism resulting from several possible mutations in the gene coding for iduronate-2-sulfatase (IDS), which leads to a great clinical heterogeneity presented by these…
View details →Adegboye HA, Sun Y, Zhang P et al. · 2026 · Journal of the American Heart Association
Background Von Willebrand factor (VWF) and ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motif, 13) are linked to dementia risk, and limited evidence suggests apolipoprotein E ( APOE )-ε4 alters VWF release. This…
View details →Goldsmith BE, Horiuchi Y, Matush K et al. · 2025 · PNAS nexus
US democracy appears to have weakened during the 21st century. Scholars have raised concerns that this democratic backsliding will reduce favorable views of the United States among foreign citizens in other democracies. In turn, observers…
View details →Fertig A, Hartman A, Iyer L et al. · 2026 · The journal of politics
Can financial incentives lead households to register land in women's names, thereby providing them with formal property rights? Can formal property ownership improve women's economic outcomes and change decision-making dynamics within the…
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