11,317 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Weilnhammer V · 2024 · Neuroscience of consciousness
The neurobiology of conscious experience is one of the fundamental mysteries in science. New evidence suggests that transcranial magnetic stimulation of the parietal cortex does not modulate bistable perception. What does this mean for the…
View details →Ramaswamy A, Yamamori Y, Vivekananda U et al. · 2026 · Computational psychiatry (Cambridge, Mass.)
Anhedonia, a transdiagnostic symptom marked by diminished reward sensitivity, is often linked to impairments in reinforcement learning (RL). Standard tasks (e.g., the 4-arm bandit) can place substantial demands on participants and may blur…
View details →Burkard T, Holmberg D, Thorell A et al. · 2022 · Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Background Obesity is considered a risk factor for cataracts. The association between weight loss and a cataract among patients with obesity has not been assessed to date. Objectives To assess the association between weight loss following…
View details →Cassar A, Hobbs A, Anttila-Hughes J et al. · 2026 · PNAS nexus
A consistent finding regarding human societies is that higher temperatures lead to antisocial behavior, including more crime, violence, aggression, and civil conflict. A large body of research documents this relationship at the societal…
View details →Li ZL, Zou YW, Jia PW et al. · 2026 · Food science & nutrition
Growing research implicates the diet-microbiota-joint axis plays a key role in joint health. The Dietary Index for Gut Microbiota (DI-GM) is a novel metric evaluating dietary effects on microbial communities, yet its potential link to…
View details →Wu J, Hang R, Xin P et al. · 2026 · Brain sciences
Background: Proficient second language (L2) reading relies on complex neurocognitive processes. Neuroimaging studies have identified key brain regions recruited during L2 reading, including the left inferior parietal lobule (LIPL) and the…
View details →Kırkgeçit M, Türkoğlu H, Yüzbaşı MF et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : We aimed to determine whether preoperative systemic inflammatory markers derived from complete blood count differ between patients with intradural spinal tumors and healthy controls, and whether any such…
View details →Ezquina SAM, Jones M, Dicks E et al. · 2025 · American journal of epidemiology
Common genetic variation throughout the genome and rare coding variants identified to date explain about half of the inherited genetic component of epithelial ovarian cancer risk. It is likely that rare variation in the noncoding genome…
View details →Pawel S, Heyard R, Micheloud C et al. · 2024 · eLife
In several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a 'replication success.' Here, we discuss the logical problems with this approach:…
View details →Farhan MA, Makkiyah FA, Hadiwiardjo YH et al. · 2025 · BMC medical education
Objective This study examines the relationship among medical students' academic achievement, self-regulated learning, and critical thinking ability. Methods This study employed a cross-sectional analytical design involving 120 medical…
View details →Sangroungrai A, Atipiboonsin V, Sukhonthamarn K et al. · 2025 · Arthroplasty (London, England)
Background Intraoperative periprosthetic femur fracture is a serious complication in hip arthroplasty, affecting patient outcomes. This study explored the biomechanical properties of the proximal femur, specifically comparing prophylactic…
View details →Yang W, Li Z, Chen X et al. · 2026 · Clinics (Sao Paulo, Brazil)
Background Diet plays a key role in regulating the gut microbiota. This study aimed to investigate the association between the Dietary Index of the Gut Microbiome (DI-GM) ‒ a score designed to reflect the potential of a diet to support a…
View details →Rajaraman R, Kassaye I, Sharma SS et al. · 2026 · Antimicrobial agents and chemotherapy
The aim of this study was to determine the antiamoebic efficacy of povidone-iodine when used as an adjunct to topical biguanide therapy for Acanthamoeba keratitis. Patients with smear- or culture-positive Acanthamoeba keratitis received…
View details →Pinto R, Ferreira R, Alves P et al. · 2025 · Healthcare (Basel, Switzerland)
Background : Healthcare-associated infection drives morbidity and unplanned hospital use in haemodialysis. We aimed to determine whether an adapted British Renal Society Infection Risk Screening Tool, applied during a nurse-led vascular…
View details →Andrade G, Gamboa L, Campo-Redondo M · 2026 · Frontiers in psychology
Background Beliefs about free will are central to philosophical and scientific conceptions of agency, and experimental work suggests that weakening such beliefs can reduce honesty, self-control, and helping. Yet little is known about how…
View details →Chen C, Zhang W, Chu C et al. · 2026 · Gland surgery
Background Thyroid malignancies pose a significant global health burden, especially in women. Sex hormones are crucial for thyroid function, but their relationship with thyroid malignancy remains unclear. This study investigates the causal…
View details →Hamilton F, Mitchell RE, Constantinescu A et al. · 2023 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Severe malaria remains a deadly disease for many young children in low- and middle-income countries. Levels of interleukin (IL)-6 have been shown to identify cases of severe malaria and associate with severity, but it is unknown…
View details →Oda T, Houshmand Chatroudi A, Yotsumoto Y · 2026 · Journal of vision
Flicker-induced time dilation refers to the robust illusion whereby temporally modulated visual stimuli are perceived as lasting longer than static stimuli. Although flicker-induced time dilation has been consistently demonstrated, it…
View details →Xu X, Zang X, Liu H et al. · 2026 · The Journal of international medical research
ObjectiveTo assess the causal effects of specific eating habits on ischemic stroke risk and functional outcomes using Mendelian randomization.MethodsThis two-sample Mendelian randomization study used genetic variants associated with 32…
View details →Lin WT, Yang JL, Lin CY et al. · 2026 · JAC-antimicrobial resistance
Objectives Among patients with daptomycin-resistant and vancomycin-resistant Enterococcus faecium bloodstream infection (BSI), the optimal definitive therapy is uncertain. We estimated the dose effect of daptomycin (≥11 mg/kg versus 8 to…
View details →Ünal K, Taş Torun Y, Erol ME et al. · 2026 · World journal of clinical pediatrics
Background Generalized anxiety disorder (GAD) is a prevalent psychiatric condition in children and adolescents, frequently linked to difficulties in daily functioning and academic performance. Increasing evidence suggests that immune…
View details →Michel C, Langeloh M, Tünte MR et al. · 2025 · PloS one
Violation of expectation (VOE) paradigms are key to understanding infants' early knowledge. In VOE paradigms, infants are presented sequences of events either according with or violating regularities of their physical or social…
View details →Gurbuz E, Rohr M, Wentura D · 2024 · Experimental psychology
Research on automatic evaluative responses to faces varying in emotional expression and ethnicity has yielded conflicting results. Some paradigms, like the Approach/Avoidance task, demonstrated interactive evaluation. In contrast, recent…
View details →Chitic D, Zdravkov KS, Dounavi V et al. · 2026 · The European journal of neuroscience
Long-term memory (LTM) has been associated with neural oscillation in the theta (3-8 Hz) range. Although previous studies have suggested that the dorsomedial prefrontal cortex (dmPFC) is a core region for LTM retrieval, causal evidence is…
View details →Wolff A, Feneberg E, Shakhtour J et al. · 2026 · PloS one
Background Chronic inflammatory bowel diseases, encompassing Crohn's disease and ulcerative colitis, are characterized by persistent inflammation of the gastrointestinal tract. While traditionally regarded as confined to the gut, the…
View details →Chen J, Chen Z, Yan Q et al. · 2025 · BMC oral health
Objectives To evaluate patient-reported outcome measures (PROMs) of povidone-iodine rinse and chlorhexidine rinse for patients undergoing dental implant treatments, as well as their bacteriostatic efficacy. Materials and methods Patients…
View details →Saminathen MG, Lundin A, Raninen J et al. · 2026 · BMC public health
Background Parenting practices, such as emotional support and warmth, are key determinants of adolescent mental health, whereas the role of parental knowledge is less well understood. Parental warmth is thought to foster openness and…
View details →Li J, Lee P, Jones BC et al. · 2025 · PloS one
The tendency for men to find younger adult women more attractive has been hypothesised to reflect preferences for cues of reproductive potential. To further test this hypothesis, we investigated the possible relationship between…
View details →McKean J, Underwood P, Yasinzai AQK et al. · 2026 · Cancers
Background/objectives Pancreatic ductal adenocarcinoma is an aggressive malignancy with poor long-term survival. While surgical resection followed by adjuvant chemotherapy remains the standard of care for resectable disease, a substantial…
View details →Sadil P, Cowell RA, Huber DE · 2024 · Psychonomic bulletin & review
In the "serial dependence" effect, responses to visual stimuli appear biased toward the last trial's stimulus. However, several kinds of serial dependence exist, with some reflecting prior stimuli and others reflecting prior responses.…
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