11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Gallardo VJ, Caronna E, Rosell-Mirmi J et al. · 2026 · The journal of headache and pain
Background It remains unclear whether high-frequency migraine is associated with objective markers of possible neuroaxonal injury and potential expression of neurodegenerative hallmarks. We compared serum and MRI biomarkers in…
View details →Abel DB, Fulford D, Fiszdon JM · 2026 · The Journal of nervous and mental disease
Aim Researchers have studied mechanisms underlying social motivation in schizophrenia, including reward learning, hostile attribution bias, and defeatist performance beliefs. Yet, existing work is limited by the use of laboratory paradigms…
View details →McCabe SC, Ramirez K, Dyer S et al. · 2026 · American journal of audiology
Purpose Follow-up care after hearing aid fitting is recommended, yet clinicians lack data on the expected number of follow-up appointments needed and which patients require more support. This study aimed to characterize follow-up service…
View details →Fernández Pérez ER, Humphries SM, Lynch DA et al. · 2026 · Annals of the American Thoracic Society
Rationale Quantitative CT using multiple instance learning (MIL)-usual interstitial pneumonia (UIP) classifier and data-driven textural analysis (DTA) provides objective and reproducible measurements of disease pattern and extent,…
View details →Berkley S, Hoyt LT, Zeiders KH et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence
This study used multilevel growth modeling to examine associations between ethnic-racial socialization (ERS) and sociopolitical development among undergraduates of color (N = 125) attending predominantly White institutions during the 2016…
View details →MacAllister WS, Désiré N, Brooks BL · 2026 · The Clinical neuropsychologist
Objective There is strong support for the use of performance validity tests (PVTs) in all neuropsychological evaluations, however, research examining racial, ethnic, and linguistic differences in failure rates remains scarce, particularly…
View details →Cronblad IA, Warvik CE, Bjerkli IH et al. · 2026 · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Background Oral tongue squamous cell carcinomas (OTSCC) frequently metastasise via lymphatic vessels, thus lymphangiogenesis may enhance tumour cell dissemination by increasing tumour-lymphatic interactions. The prognostic significance of…
View details →Pfeiffer JP, Pinquart M, Neubauer BA · 2026 · Epilepsy & behavior : E&B
Objective Using strategies for achieving age-specific goals is essential for developmental regulation. In a previous study, we demonstrated that adolescents with epilepsy have difficulty achieving some of their goals, which necessitates…
View details →Balousis P, Abood SK, Brazeau L et al. · 2026 · Frontiers in veterinary science
Introduction Raw meat-based diets (RMBD) are increasingly popular among dog guardians, yet the role of personal nutrition habits and pet-guardian relationships in their adoption remains unclear. This study examines how these factors,…
View details →Najjar E, Khan S, Quraishi NA et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Background Cage subsidence is a common radiographic finding following transforaminal lumbar interbody fusion (TLIF), but its clinical relevance remains uncertain. Hounsfield Unit (HU) values from preoperative CT scans have emerged as…
View details →Ballinger TJ, Zhao F, Jiang G et al. · 2026 · Cancer
Background Black patients with breast cancer experience higher rates of taxane-induced peripheral neuropathy (TIPN), which may compromise chemotherapy dose delivery and health-related quality of life (HRQOL). Using the prospective…
View details →Fosstveit SH, Feron J, Lohne-Seiler H et al. · 2026 · BMC sports science, medicine & rehabilitation
Background High-intensity interval training (HIIT) was originally designed to improve athletic performance, but a growing body of research over the past decade has highlighted its positive impact on various other health outcomes. However,…
View details →Lemos C, Vargas F, Donald EM et al. · 2026 · Journal of cardiac failure
Background Women, racial and ethnic minority groups, and patients of low socioeconomic status (SES) face barriers linked to adverse outcomes after heart transplantation (HT). Data are lacking regarding the association of these demographics…
View details →Sahlan RN, Frietchen R, Billman Miller MG et al. · 2025 · Suicide & life-threatening behavior
Objective Although previous research has established bidirectional links between many eating disorder (ED) symptoms and suicidal ideation (SI), no research has examined how symptoms of avoidant/restrictive food intake disorder (ARFID)…
View details →Hauser N, Sommerfield D, Nguyen J et al. · 2026 · Anaesthesia
Introduction Peri-operative respiratory adverse events remain a major cause of morbidity and mortality in children undergoing general anaesthesia; those with asthma are at higher risk. The aim of this feasibility study was to determine…
View details →Li M, He H, Dong L et al. · 2026 · Journal of psychosomatic research
Background Patients post hepatocellular carcinoma (HCC) surgery encounter physiological challenges as well as psychological and social adaptation problems，yet the trajectory and predictors of their psychosocial adjustment (PSA) remain…
View details →Tezanos KM, Simeone A, Gerson R et al. · 2026 · Child psychiatry and human development
Youth are presenting to Emergency Departments (EDs) following a suicide-related crisis at higher rates and younger ages. Clinicians lack tools to effectively discern suicide risk in younger patients. The present investigation examines how…
View details →Joshi S, Jahn KN · 2026 · Ear and hearing
Objectives Cochlear implants (CIs) enable people with moderate-to-profound sensorineural hearing loss to perceive sounds, but perceptual outcomes with a CI remain highly variable from person to person. Individuals who wear their CI…
View details →Ciriello GD, Colonna D, Morelli C et al. · 2026 · Indian pacing and electrophysiology journal
Fetal echocardiography plays a pivotal role in the diagnosis and management of fetal arrhythmias, allowing evaluation of the electrophysiological mechanism and guiding appropriate medical therapy. Herein, we describe our ten-year…
View details →Chan ACY, Stephan AT, Sneed RS · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences
Objectives While the intensity of grandparent caregiving has been linked to older adults' health, limited research has examined the bidirectional associations between grandparenting intensity and health, particularly within grandparent…
View details →Kula O, Machluf Ruttner R, Shahar B et al. · 2026 · Psychotherapy (Chicago, Ill.)
The primary proposed change process in emotion-focused therapy models for couples involves partners accessing and revealing vulnerable emotions and responding to such disclosures with empathy and compassion. Therapists often use enactments…
View details →Chawner LR, Kidby S, Filippetti ML · 2026 · Appetite
Parental feeding practices, child temperament, and poor emotion regulation abilities are central factors associated with Emotional Eating (EE) during childhood (3–10 years). Yet, it is poorly understood how children develop EE behaviours…
View details →Özden HÖ, Çelik FND, Üstüner FŞ et al. · 2026 · Diagnostics (Basel, Switzerland)
Background: Abrupt cessation of deep brain stimulation (DBS) in Parkinson's disease (PD), most commonly due to implantable pulse generator (IPG) battery depletion, may lead to DBS withdrawal syndrome (DBS-WDS). However, withdrawal syndrome…
View details →Morel M, Mitchell L, Stienen E et al. · 2026 · Proceedings. Biological sciences
The post-fledging period is a critical phase for inexperienced birds, who must navigate and explore unfamiliar environments to locate essential resources for survival. Successful foraging during this stage relies on acquiring spatial…
View details →O'Shaughnessy J, Brufsky AM, Layeequr Rahman R et al. · 2026 · JCO precision oncology
Purpose Randomized trials have not demonstrated clear benefit from anthracyclines for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HER2-) early breast cancer (EBC). The MammaPrint 70-gene…
View details →Xiao H, Warner E, Ryan J et al. · 2026 · Cancer causes & control : CCC
Purpose Cancer-related cognitive impairment (CRCI) is a common concern among breast cancer (BC) patients receiving chemotherapy, yet predictors of short-term cognitive change remain unclear. This study examined whether baseline…
View details →William JB, Chieng D, Crowley R et al. · 2026 · JACC. Clinical electrophysiology
Background Left atrial (LA) enlargement is commonly used in patient selection for catheter ablation. However, its role in predicting postablation outcomes in persistent atrial fibrillation (AF) remains uncertain. Objectives The study goal…
View details →Alpert E, Kaplan A, Nelson D et al. · 2026 · Psychological trauma : theory, research, practice and policy
Objective Among patients with co-occurring posttraumatic stress disorder (PTSD) and substance use disorders (SUDs), little is known about early PTSD treatment processes, including treatment preference and outcome expectancy. This study…
View details →Cohen H, Toro D, Zuluaga D et al. · 2026 · Clinical transplantation
Introduction To evaluate donor-stratified graft and patient survival following kidney transplantation (KT) for lithium-associated end-stage kidney disease (ESKD). Methods This retrospective analysis utilized the Organ Procurement and…
View details →Yang L, Zhang H, Wei Y et al. · 2026 · American journal of hematology
Immunosuppressive therapy (IST) is the standard treatment for acquired pure red cell aplasia (aPRCA), but predictors of treatment response and long-term prognosis remain unclear. The clinical significance of somatic mutations in aPRCA is…
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