11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Resnick E, Travers C, Griffin R et al. · 2026 · Pediatric nephrology (Berlin, Germany)
Background Extremely low gestational age neonates (ELGANs) remain at high risk for morbidity and mortality. Acute kidney injury (AKI) is increasingly recognized, but data in the most immature neonates, especially those born at 22-23 weeks,…
View details →Yılmaz U, Buzdağlı Y, Bilgin S et al. · 2026 · Journal of strength and conditioning research
Abstract Yılmaz, U, Buzdağlı, Y, Bilgin, S, Sepil, Y, Ozan, M, Bağaçlı, UH, Şıktar, E, Baygutalp, F, and Kılıç Baygutalp, N. Multidimensional physiologic adaptations to a 14-day detraining period in elite powerlifters: Neuromuscular,…
View details →Benli O, Avşar MK · 2026 · Pediatric cardiology
Isolated (IHV) drainage can prevent uniform delivery of hepatic venous effluent to the pulmonary circulation after Fontan completion, predisposing to pulmonary arteriovenous malformations (PAVMs), hypoxemia, and thrombosis. Comparative…
View details →Rochlin DH, Chen J, Cole-Price A et al. · 2026 · Plastic and reconstructive surgery
Background The objectives of this study were to determine if financial considerations affect reconstructive decision-making, and conversely if reconstructive choice affects downstream financial burden. Methods We conducted mixed-methods…
View details →Avcı EA, Bülbül GA, Tsakır B et al. · 2026 · BMC pregnancy and childbirth
Background Accessory renal arteries (ARAs) are recognized as an extrinsic cause of hydronephrosis in children; however, their relationship with prenatally detected hydronephrosis remains unclear. This prospective study aimed to evaluate…
View details →Okur KT, Abdulaliyev F, Yalçın S et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Acetabular fracture surgery is associated with substantial perioperative blood loss and prolonged operative time. Routine preoperative pelvic computed tomography (CT) carries information about body composition…
View details →Connor CH, Katsnelson JY, Paul BJ et al. · 2026 · Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Periprosthetic infection is a frequent complication of implant-based breast reconstruction, often resulting in implant removal, additional surgery, and increased costs. This study evaluated whether polymethyl methacrylate (PMMA) discs…
View details →Schibler D, Hinkelmann MA, Frei F et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
INTRODUCTION: Hook plates remain controversial in the management of lateral clavicle fractures despite their biomechanical advantages. Concerns include implant-related complications, subacromial irritation, and the need for routine implant…
View details →Ding X, Wang Y, Choi M et al. · 2026 · Clinical oral implants research
Objective The objective of this study is to evaluate the clinical efficacy of angulated single-implant crowns using the hybrid retention versus pure screw-retained restorations in the aesthetic area. Materials and methods A retrospective…
View details →Yang H, Gao J, Mo S et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Objective and background The optimal surgical strategy for patients with hepatocellular carcinoma (HCC) and liver fibrosis/cirrhosis presenting with a future liver remnant to standard liver volume (FLR/SLV) ratio of 30%-40% remains a…
View details →Süleyman S, Emin P, Hüseyin A et al. · 2026 · Journal of clinical medicine
Background/Objectives: Acute severe ulcerative colitis (ASUC) is a high-risk condition associated with intense inflammation and a substantial risk of early colectomy. Intravenous steroids (IVS) remain the first-line therapy; however,…
View details →Leizaola-Cardesa IO, Gómez-Moreno G, Hernando J et al. · 2026 · Journal of stomatology, oral and maxillofacial surgery
Background To determine serum parathyroid hormone (PTH), vitamin D, and calcium levels in patients with medication related osteonecrosis of the jaw (MRONJ), compared with patients receiving similar medication but without MRONJ; also, to…
View details →Darroudi S, Ghazaee H, Babaei N et al. · 2026 · Scientific reports
Empagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, has demonstrated cardioprotective effects beyond glycemic control. Empagliflozin has anti-inflammatory and antioxidant effects in long-term administration; however, current…
View details →Eslami M, Ermolaev N, Kronberger C et al. · 2026 · Scientific reports
Fibroblast growth factor 23 (FGF23), a bone-derived hormone, is emerging as a potential biomarker in cardiovascular disease. However, its role in transthyretin amyloid cardiomyopathy (ATTR-CM), a progressive infiltrative cardiomyopathy,…
View details →Marković F, Bojić Z, Stjepanović M et al. · 2026 · Cancers
Background: Immune checkpoint inhibitor monotherapy targeting the PD-1/PD-L1 axis is a standard first-line treatment option for patients with metastatic non-small cell lung cancer (NSCLC) and high PD-L1 expression. However, comparative…
View details →Chow SCW, Wang Y, Leung OLK et al. · 2026 · Journal of autism and developmental disorders
Purpose This study investigated the risk of ASD and ADHD in children who have survived hypoxic-ischemic encephalopathy (HIE), one of the common conditions during birth resulting in neonatal brain injury. Methods A population-based cohort…
View details →Çakır B, Polat F, Karataş MB et al. · 2026 · Acta diabetologica
Background Diabetic cardiomyopathy (DCM) frequently begins with diastolic dysfunction (DD), which leads to increased left ventricular filling pressures and subsequent left atrial enlargement, quantified by the left atrial volume index…
View details →Kilavuz A, Zorbozan O, Yildirim Simsir I et al. · 2026 · BMC nutrition
Background Recent evidence suggests that the gut microbiota plays a crucial role in the development and progression type 2 diabetes mellitus (T2DM). This study aimed to investigate the effects of multi-strain probiotic supplementation on…
View details →Tajima Y, Kubota M, Yoshida Y et al. · 2026 · World neurosurgery
Objective This study aimed to evaluate the impact of embolic protection strategies on outcomes in asymptomatic patients undergoing carotid artery stenting (CAS). Methods We retrospectively analyzed 312 consecutive asymptomatic patients…
View details →Feigin L, Feigin E, Bronstein Y · 2026 · The American journal of medicine
Background This study was conducted to examine whether a "weekend effect" exists in internal medicine departments of a large tertiary medical center in Israel. Methods We conducted a retrospective cohort study of patients > 18 admitted to…
View details →Urasheva Z, Khamidulla A, Yermagambetova A et al. · 2026 · Georgian medical news
Background Ischemic stroke is a major cause of death and disability worldwide. Recent evidence highlights the role of systemic inflammation in stroke pathophysiology and prognosis. The neutrophil-to-lymphocyte ratio (NLR), an accessible…
View details →Cernes R, Hershkovich O, Tsehovsky T et al. · 2026 · The Israel Medical Association journal : IMAJ
Background Gait disturbances are common in patients undergoing hemodialysis and are associated with increased fall risk, mobility decline, and adverse health outcomes. Prior research suggests that hemodialysis may impact gait parameters…
View details →Ugurluoglu G, Ulutas Z, Yigit Y et al. · 2026 · Echocardiography (Mount Kisco, N.Y.)
Objective This study aimed to evaluate right ventricular (RV) function pre and post bone marrow transplantation (BMT) using transthoracic echocardiography (TTE), in order to detect subclinical or clinical RV dysfunction that may occur in…
View details →Franks E, Rigdon J, Kennelly M et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Importance Intradetrusor chemodenervation with onabotulinumtoxinA (BOTOX) injections, a common office-based procedure for overactive bladder (OAB), is associated with patient anxiety and discomfort. Aromatherapy and music have been shown…
View details →Angelopoulou T, Bobetsis YA · 2026 · Journal of clinical medicine
Background/Objectives : Celiac disease (CD) is a chronic, immune-mediated enteropathy induced by dietary gluten exposure in genetically predisposed individuals. Along with non-celiac gluten sensitivity (NCGS), these disorders present with…
View details →Shen W, Cui J, Ji Y et al. · 2026 · World neurosurgery
Background Sagittal synostosis (SS) is the premature closure of sagittal sutures. To investigate the use of absorbable plates as internal attachment points for external spring (ES) traction in the treatment of sagittal craniosynostosis in…
View details →Sanda NA, Filip PV, Bobirca FT et al. · 2026 · Diagnostics (Basel, Switzerland)
Background: The role of primary anastomosis in rectal cancer surgery remains debated, particularly due to concerns regarding postoperative morbidity. Evidence from randomized trials is limited, and observational studies are frequently…
View details →García-Sáenz MR, Castro-Murillo JI, Mercado M et al. · 2026 · Archives of medical research
Introduction Predicting resistance to cabergoline in prolactinomas remains a challenge. While prolactin (PRL)-based ratios help differentiate prolactinomas from non-functioning pituitary adenomas (NFPAs), their role in forecasting…
View details →Aydın Güçlü Ö, Demirdöğen E, Hunutlu FÇ et al. · 2026 · BMC infectious diseases
Background Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality among immunocompromised patients, particularly those with hematologic malignancies. The present study aims to evaluate the clinical features,…
View details →Lee A, Higgins S, O'Driscoll D et al. · 2026 · Journal of autism and developmental disorders
OBJECTIVE: To examine the association between neonatal jaundice requiring hospital treatment and autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in offspring by age 14 years. METHODS: We used data from…
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