11,416 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Senoo K · 2025 · Journal of cardiovascular electrophysiology
Atrial fibrillation (AF) is the most common sustained arrhythmia and raises ischemic stroke risk fivefold, even when asymptomatic. Early detection and timely initiation of oral anticoagulation can significantly reduce stroke incidence,…
View details →Patel A, Esencan E, Lakhani Z et al. · 2026 · F&S reports
Objective To report an adult case of XX/XY chimera resulting from in vitro fertilization with transfer of three embryos, that was discovered with preconception genetic carrier screening. Design Case report. Subject A 33-year-old…
View details →Phommasone K, Souksakhone C, Chanthongthip A et al. · 2025 · PloS one
Background Lao PDR reported a low number of confirmed SARS-CoV-2 cases until the introduction of COVID-19 vaccines in April 2021. This raised doubts about whether the reported number reflected the true situation and questioned about…
View details →Carrillo Lizarazo JL, Cecchin D, Camozzi V et al. · 2025 · BJS open
Background Accurate preoperative localization is essential for successful, focused, minimally invasive surgery in primary hyperparathyroidism (PHPT). New imaging techniques have recently been proposed. This study evaluated the impact of…
View details →Wang L, Xue C, Zhu B et al. · 2026 · Journal of nutritional science and vitaminology
Data regarding to how serum 25 hydroxyvitamin D (25(OH)D) levels affect muscle mass and function in end-stage renal disease (ESRD) patients have led to inconclusive results. The main goal of this research was to examine the relationship…
View details →Shiba Y, Aoki K, Ohka F et al. · 2025 · AJNR. American journal of neuroradiology
Background and purpose Differentiating between a brain tumor and a nontumorous lesion remains a diagnostic challenge, particularly when conventional imaging modalities such as CT and MRI provide inconclusive results. While 11 C-methionine…
View details →Kumar R, Gravett S, Jelic V et al. · 2026 · Neurology
Background and objectives The α-synuclein (α-syn) seed amplification assay (SAA) has shown promising results for diagnosing dementia with Lewy bodies (DLB) using CSF samples. A barrier to implementing α-syn SAA clinically is the use of…
View details →Tornvall S, Blomberg L, Hirschberg AL · 2025 · Psychoneuroendocrinology
The objective of this study was to investigate the association of menstrual cycle phases on sexual function, well-being, and mood in young healthy women. Previous research has shown inconclusive results likely due to using non-validated…
View details →Wilcox A, Hall M, Menzies J et al. · 2025 · Science of the Total Environment
The biodegradability of water-soluble carboxymethyl cellulose (CMC) polymer, degree of substitution of 0.65, was evaluated in screening and simulation assays using activated sludge as the inoculum. In an OECD 301B, CMC 0.65 was slowly…
View details →Abdulrasak M, Axler O, Kapás B et al. · 2026 · Diagnostics (Basel, Switzerland)
Protein-losing enteropathy (PLE) is an uncommon and often underrecognized manifestation of lymphoproliferative disorders and may be difficult to diagnose when conventional gastrointestinal investigations are unrevealing. We present an…
View details →Maffezzoli M, Nagpal R, Elewaily M et al. · 2025 · Current oncology reports
PURPOSE OF REVIEW: Adjuvant immunotherapy has improved outcomes in several cancers, although patient selection and toxicity remain challenges. Circulating tumor DNA (ctDNA) has emerged as a biomarker for minimal residual disease (MRD)…
View details →Viderman D, Kalikanov S, Mazhibiyeva A et al. · 2026 · Frontiers in pain research (Lausanne, Switzerland)
Background and objectives Chronic knee pain is highly prevalent in various knee diseases. It significantly decreases patients' quality of life. Among non-surgical interventions, exercise is considered a promising approach for alleviating…
View details →Planello AC, Loureiro T, Alencar-Cupertino D et al. · 2025 · Revista da Associacao Medica Brasileira (1992)
Objective This study aimed to evaluate whether the increased use of exome sequencing as a primary next-generation sequencing test provides a higher diagnostic yield compared to multi-gene panels for various clinical indications within a…
View details →Mansikkaniemi L, Stewart JA, Sinisalo J et al. · 2025 · Scandinavian cardiovascular journal : SCJ
Background. Invasive coronary angiography (ICA) is the gold standard in evaluating stent patency after percutaneous coronary intervention (PCI), but it carries a risk of potentially life-threatening complications. Third-generation coronary…
View details →Naim S, Sraidi S, Salam S et al. · 2025 · Clinical case reports
We present a rare case of bone metastatic Neuroblastoma without a diagnosis of an identifiable primary lesion in a 16-year-old patient who presented with intermittent right knee pain and soft tissue swelling for 7 months. Initial…
View details →Sabatini P, Zhang T, Boruvka N et al. · 2025 · American journal of clinical pathology
Objective Somatic hypermutation at immunoglobulin heavy chain variable (IGHV) genes, an established prognostic and predictive biomarker for chronic lymphocytic leukemia (CLL), is assessed by gene sequencing. We developed a single…
View details →Holopainen A, Verhage ML, Schuengel C et al. · 2025 · Journal of reproductive and infant psychology
Background Fear of childbirth and negative birth experiences have suggested to been associated with parenting behaviour and thereby indirectly with child outcomes. The current study contributes to this knowledge by investigating fear of…
View details →Young RP, Ward RC, Scott RJ et al. · 2025 · Annals of the American Thoracic Society
Rationale: Current eligibility criteria for lung cancer (LC) screening are derived from randomized controlled trials and largely based on age and smoking history. However, the individualized benefits of screening are highly variable and…
View details →Garabedian C, Girault A · 2025 · Journal of gynecology obstetrics and human reproduction
Fetal monitoring during labor is crucial for detecting potential hypoxic situations that could lead to severe outcomes like cerebral palsy or peripartum death. The current standard, fetal heart rate (FHR) monitoring, is subjective and…
View details →Racano E, Spinelli C, Sacco G et al. · 2026 · Scientific reports
Early detection and documentation of anterior segment opacities in infants (aged 1–6 months) is limited by resource constraints and specialist availability. This study aimed to evaluate the usefulness of digital infrared reflex testing…
View details →Shah KV, Jung C, Talian D et al. · 2025 · OTO open
Objective While the etiology of Meniere's disease (MD) is likely multifactorial, genetics are thought to play a role. Several previous studies have yielded inconclusive results, potentially due to phenotypic uncertainty and variable…
View details →Nguyen MD, Park D, Scott JW et al. · 2026 · Science advances
Landau predicted that transverse sound propagates in a Fermi liquid with sufficiently strong interactions such as for liquid 3 He, unlike a classical fluid that cannot support shear oscillations. Previous attempts to observe this unique…
View details →Gay A, Laudet F, Meynard P et al. · 2026 · Orthopaedics & traumatology, surgery & research : OTSR
Introduction Infection is a significant and challenging complication of total hip and knee arthroplasties. Diagnosing chronic periprosthetic joint infection (PJI) can be difficult, particularly when joint aspiration yields inconclusive…
View details →Payton C, Kvaratskhelia N, Chalfin M et al. · 2025 · Journal of immigrant and minority health
Cancer screening can detect cancer at an early stage and decrease cancer morbidity and mortality. Refugee populations may have had limited access to cancer screening before arrival in the United States. A cross-sectional analysis of…
View details →Kaseb A, Benider H, Treglia G et al. · 2025 · European journal of clinical investigation
Background 4D-CT has garnered attention as complementary imaging for patients with primary hyperparathyroidism (pHPT). Herein we evaluated a diagnostic strategy using [ 18 F]Fluorocholine Positron Emission Tomography/Computed Tomography…
View details →Kuyucu M, Erdogan KM, Adiyaman D et al. · 2025 · Medicine
This study shares our 5-year experience with chorionic villus sampling (CVS) and analyzes the indications, results, and complications of this procedure. We conducted a retrospective analysis of data from singleton pregnancies that…
View details →Shebli B, Ghabally M, Shabouk MB et al. · 2025 · Frontiers in cardiovascular medicine
Background Beta-agonists like Levalbuterol and Albuterol are used in the treatment of Hyperkalemia. However, few studies in the medical literature have directly compared the cardiac effects and potassium-lowering efficacy of levalbuterol…
View details →Cohen M, Slae M, Gamliel A et al. · 2025 · Respiratory medicine
Background -Nasal Potential Difference (NPD) is an established diagnostic tool for CF. However, standardized values for very young patients are lacking. Aim - To evaluate the feasibility of performing NPD testing in young children. Methods…
View details →Chen Y, Bhatti P, Dummer T et al. · 2025 · Cancer epidemiology
Background Studies of the relationship between diabetes medications and pancreatic cancer risk have produced inconclusive results. We aimed to examine associations between classes, subclasses, and individual diabetes medications with…
View details →Baldini GM, Ferri D, Lot D et al. · 2026 · Gynecologic and obstetric investigation
Objectives The objective of the study was to evaluate the impact of male human papillomavirus (HPV) sexually transmitted infection on sperm parameters, embryo morphokinetics, and clinical pregnancy outcomes in assisted reproductive…
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