11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ragamin A, Schappin R, Pasmans SGMA et al. · 2023 · Skin health and disease
National prescription data for therapeutic clothing in atopic dermatitis was analysed to investigate the role of therapeutic clothing in atopic dermatitis. Therapeutic clothing is most frequently prescribed by dermatologists in a hospital…
View details →Merlo JK, da Silva AV, Casonatto J et al. · 2024 · Healthcare (Basel, Switzerland)
Objective To investigate the effects of combining a Pilates program with photobiomodulation therapy (PBMT) in patients with chronic nonspecific low back pain (CNLBP). Methods Thirty-eight adults with CNLBP were randomly assigned to two…
View details →Stroemel-Scheder C, Lautenbacher S · 2023 · The journal of pain
Recent research suggests that recovery sleep (RS) has the potential to restore pain sensitivity and modulation after hyperalgesia due to preceding sleep deprivation. However, it has not yet been systematically examined whether the…
View details →Moretti L, Richelmi L, Cosentini D et al. · 2024 · Breast (Edinburgh, Scotland)
The efficacy of adjuvant denosumab in combination with hormonotherapy in breast cancer patients was investigated in two randomized trials, ABCSG-18 and D-Care, but the results were mixed with respect to the impact of this drug on…
View details →Góis KS, Braga M, Souza VH et al. · 2026 · Einstein (Sao Paulo, Brazil)
Objective This study aimed to analyze the possible association between rs2814778, rs12075 ( ACKR1 gene), and rs4073 ( CXCL8 gene) single nucleotide variants and COVID-19 severity. Methods This cross-sectional study included 319 COVID-19…
View details →Hosier H, Lipkind HS, Rasheed H et al. · 2023 · Hypertension (Dallas, Tex. : 1979)
Background Preeclampsia is a leading cause of maternal morbidity, and dyslipidemia has been associated with preeclampsia in observational studies. We use Mendelian randomization analyses to estimate the association between lipid levels,…
View details →Richardson KE, Suo C, Albertella L et al. · 2025 · JAMA psychiatry
Importance Cannabis is the most commonly used illicit drug, with 10% to 30% of regular users developing cannabis use disorder (CUD), a condition linked to altered hippocampal integrity. Evidence suggests high-intensity interval training…
View details →da Silva NIS, de Araújo TLAC, Firmino SS et al. · 2026 · Tropical animal health and production
This study aimed to evaluate the effects of supplementing high-concentrate diets for sheep with green propolis extract (PRO) from Mimosa tenuiflora or with salinomycin (SAL) on feed intake, apparent digestibility, nitrogen balance, and…
View details →Luzuriaga AL, Madrigal-González J, de la Cruz M et al. · 2026 · Ecology
The relationship between taxonomic and phylogenetic diversities remains underexplored. Our goal was to determine whether a causal link exists between species richness and phylogenetic diversity and to determine the direction of this…
View details →Lo Verso L, Lessard M, Lauzon K et al. · 2026 · Journal of animal science
This study aimed to determine the effects of deoxynivalenol (DON) and zearalenone (ZEA) co-contamination on systemic immune responses and intestinal mucosal immunity in weaned piglets and to evaluate the mitigating ability of antioxidant…
View details →Platzer HP, Köck A, Schobersberger W et al. · 2026 · Journal of strength and conditioning research
Abstract Platzer, H-P, Köck, A, Schobersberger, W, and Dünnwald, T. Ischemic preconditioning does not improve climbing specific performance in elite athletes. J Strength Cond Res 40(1): e69-e75, 2026-The aim of the present investigation…
View details →Mosneag IE, Rubio M, Lemarchand E et al. · 2026 · Stroke
Background Inflammation contributes significantly to neuronal damage in ischemic stroke, with IL (interleukin)-1 being a key mediator. IL-1Ra (IL-1 receptor antagonist) inhibits IL-1 signaling, successfully reducing inflammation in…
View details →Li S, De Vivo I, Davinelli S et al. · 2026 · GeroScience
Although mechanistic studies support a beneficial effect of several dietary flavonoids on telomere length (TL), to our knowledge no studies have examined associations between habitual flavonoid intakes and TL in population-based studies.…
View details →Alves Pereira D, Silva Bonatto M, Souza Santos S et al. · 2025 · Lasers in medical science
The aim of this study was to evaluate the effects of dual-wavelength photobiomodulation (PBMT) compared with antibiotic therapy with amoxicillin on postoperatory healing and symptoms after third molar extraction. Sixty patients were…
View details →Aloud A, Alzahrani H, Arzoo S et al. · 2026 · Acta pharmaceutica (Zagreb, Croatia)
This study examined the effects of omega-3 fatty acids supplementation on gut barrier integrity, systemic inflammation, neurotrans-mission and oxidative stress, in an aged rat model of propionic acid (PPA)-induced neurotoxicity.…
View details →Dong T, Sun R, Xiao J · 2026 · Revista espanola de enfermedades digestivas
Prophylactic defect closure has been considered to prevent delayed bleeding after polypectomy. However, recent evidence has demonstrated its beneficial effect is limited to those ≥20 mm proximal nonpedunculated lesions. Despite this,…
View details →Fink J, Norceide DJ, Kahlon A et al. · 2026 · JSES reviews, reports, and techniques
Background Tranexamic acid (TXA) is increasingly used in total shoulder arthroplasty to minimize perioperative blood loss; however, the quality and objectivity of evidence supporting its use remain uncertain. Systematic reviews and…
View details →Vakka A, Kyriakoulis KG, Tatakis F et al. · 2026 · Hypertension research : official journal of the Japanese Society of Hypertension
Overactivation of sympathetic nervous system (SNS) has a key role in the pathophysiology of hypertension, as well as in chronic kidney disease, heart failure, atrial fibrillation, type 2 diabetes mellitus, obstructive sleep apnea, and…
View details →Vediya N, Jain V, Sritharan P et al. · 2025 · Arthroplasty today
Background Systematic reviews (SRs) are vital for evidence consolidation in clinical research, utilized for their robust, reproducible methodology. SRs are prone to misrepresentation as they are based on primary studies and the…
View details →Lewis-Hoeber E, Darainy M, Ebrahimi S et al. · 2026 · Journal of neurophysiology
In verbal memory, retrieval cues can facilitate recall of otherwise inaccessible information. Recent work, using passive movements following a motor learning task, suggests that somatic retrieval cues similarly access motor memories. The…
View details →· 2006
Oxytocin is an essential lactation hormone released during breastfeeding that causes milk ejection and appears to have calming effect on the mother.[1] Administration of exogenous oxytocin to mothers having difficulty in breastfeeding has…
View details →Wynne R, Dharmalingam R, Omarit R et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Objectives To assess whether high flow nasal oxygen (HFNO) therapy reduces the need for endotracheal intubation in adults with acute hypoxaemic respiratory failure (AHRF) in the intensive care unit (ICU). Methods Systematic reviews were…
View details →Zhang J, Pan Q, Jin L et al. · 2026 · The British journal of ophthalmology
Aims To investigate the effect of switching to a different type of myopia control spectacles on myopia progression. Methods This retrospective matched-cohort study involved 1012 children or adolescents who were prescribed myopia control…
View details →Nagai T, Kuwaki A, Kodama K · 2026 · Nanoscale advances
Developing oxygen reduction reaction (ORR) catalysts with both high catalytic activity and durability is essential for the commercialization of polymer electrolyte fuel cells (PEFCs). One promising strategy to simultaneously enhance the…
View details →Gažarová M, Lenártová P, Kopčeková J et al. · 2026 · Nutrients
Background/Objectives: The aim of the study was to assess the metabolic response of women to a six-week consumption of full-fat sheep milk yogurt, with a focus on cardiovascular risk markers, lipid profile, and subfractions of low-density…
View details →Vogel MJ, Hacker K, Herting J et al. · 2026 · Clinical research in cardiology : official journal of the German Cardiac Society
Background Electrical cardioversion (ECV) is an effective treatment for restoring sinus rhythm in supraventricular tachycardias such as atrial fibrillation (AFib) and atrial flutter (AFlu). In clinical practice, serum potassium is often…
View details →Treat T, Jones D, Lorenzano N et al. · 2026 · Journal of periodontology
Background Evidence for whether and how non-surgical periodontal treatment (NSPT) improves systemic outcomes remains equivocal. Inconclusive findings may in part be due to design variations of randomized controlled trials (RCTs) in this…
View details →Abapolnikova M, Coyne AE, Glushka L et al. · 2026 · Psychotherapy research : journal of the Society for Psychotherapy Research
Objective Although interpersonal psychotherapy (IPT) and cognitive behavioral therapy (CBT) for depression are comparably efficacious, less is known about the respective patient-level processes that help transmit their beneficial effect.…
View details →Ersoy O, Kizilay G · 2026 · Biotechnic & histochemistry : official publication of the Biological Stain Commission
Clinical and experimental studies have shown that sitagliptin regulates blood glucose levels. This study was designed because it is thought that sitagliptin may reduce diabetes-induced apoptosis in testes by affecting blood glucose levels…
View details →Sosnówka-Czajka E, Skomorucha I, Wojtysiak D et al. · 2026 · Animals : an open access journal from MDPI
The growing greenhouse gas emissions from agricultural production are increasing the pressure on poultry producers to use practices that reduce the environmental impact of farms, mainly by reducing ammonia emissions. The study evaluated…
View details →