11,416 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Zhang Y, Zhang H, Wang Y et al. · 2026 · Cognitive processing
The influence of the interaction between accent and learning styles on learners' learning is an important issue to be considered in online animation design and application. The objective of this study is to reveal the effects of accent and…
View details →Folliard NT, Waters SM, Roskam E et al. · 2026 · Animal : an international journal of animal bioscience
The global methane (CH 4 ) pledge aims to reduce anthropogenic CH 4 emissions by 30% by 2030. Oilseed rape (Brassica napus L), a break crop with 40 million ha cultivated globally in 2022, produces fatty acid-rich by-products that could…
View details →Moussiaux IG, Vandevoorde T, Robinson M et al. · 2026 · Journal of dairy science
Increasing frequency of severe weather events such as droughts and floods may reduce the inventory of high-quality forage available for feeding dairy cattle. Thus, optimizing rumen health and milk production when feeding reduced-forage…
View details →Ünlü Ö, Görücü J · 2026 · Lasers in surgery and medicine
Objective The effectiveness of laser-etching (LE) on dentin shear bond strength (SBS) of universal adhesives remains unclear. This study aimed to compare the SBS of a nanohybrid composite resin to superficial and deep dentin following…
View details →Liu JY, Cooke JRH, Selen LPJ et al. · 2026 · The European journal of neuroscience
There are multiple methods for controlling dynamical systems under external disturbances, with some emphasizing robust performance and others prioritizing efficiency. Here, we characterized the control strategies of human steering behavior…
View details →Lee H, Sung JY, Son J et al. · 2026 · Journal of animal science and technology
In the modern swine production systems, pigs are often challenged with regrouping and vaccination, which may negatively affect growth performance and behavior of pigs. The objective was to test the hypothesis that a supplemental…
View details →Schimmele T, Castaneda NM, Mazzari G et al. · 2026 · Neuroimmunomodulation
Early life adversity (ELA) is a potent risk factor for negative mental health outcomes, in part through its enduring effects on neuroimmune function. The hippocampus is particularly sensitive to stress across the lifespan, and…
View details →Charoenphannathon JS, Royce SG, Higham Y et al. · 2026 · British journal of pharmacology
Background and purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell-derived extracellular vesicles…
View details →Maddahi N, Zamani B, Nadjarzadeh A et al. · 2026 · Urology journal
Purpose This study investigated the impact of synbiotics on blood and urinary concentrations of factors related to kidney stone formation in overweight or obese patients with hyperoxaluria. Materials and methods A randomized double-blind…
View details →Mishukov AA, Ignatova AA, Ogneva AL et al. · 2026 · Cytometry. Part A : the journal of the International Society for Analytical Cytology
Increasing evidence suggests connection between mitochondrial dysfunction and platelet-related disorders, necessitating developing of a high throughput method for assessing the functioning of mitochondria in platelets. Here we develop an…
View details →Alaoui-Ismaili Z, Grand J, Frydland M et al. · 2026 · Resuscitation plus
Background Early risk assessment is crucial in comatose survivors of out-of-hospital cardiac arrest (OHCA) for timely resource allocation and initiation of interventions. Neutrophil gelatinase-associated lipocalin (NGAL) is an inflammatory…
View details →Fida TT, Sherman T, Hall M et al. · 2026 · Biofouling
Acid-producing bacteria (APB) play significant role in pipeline corrosion by producing corrosive metabolites. Current APB mitigation strategies are often unsuccessful, costly, or not environmentally friendly. In this study, nitrate was…
View details →Bodilsen TS, Andreasen TH, Olsen MH et al. · 2026 · Acta neurochirurgica
Background Invasive multimodal neuromonitoring (MMNM) is standard of care in many neuro-intensive care units for patients with severe acute brain injury. MMNM is used for monitoring of early signs of secondary brain injury. Still, the…
View details →Lindhard K, Hansen HP, Gliese K et al. · 2026 · Clinical journal of the American Society of Nephrology : CJASN
Introduction In patients on hemodialysis, the risk of arteriovenous fistula (AVF) failure is unacceptably high. Up to 67% of AVFs need an intervention within one year after placement. There are no effective treatments to prolong AVF…
View details →Goto K, Ishizuka S, Nakamura-Takahashi A et al. · 2026 · Journal of oral biosciences
Objectives Hypophosphatasia (HPP) is a congenital disease caused by mutations in the tissue non-specific alkaline phosphatase gene. HPP is characterized by impaired hard tissue mineralization and premature tooth loss. Mild-type HPP…
View details →Van Daele A, Labarque V, Dereymaeker A et al. · 2026 · Neuropediatrics
Background Neonatal stroke is a rare but potentially severe condition that may lead to long-term neurological impairment. Several factors may influence both its occurrence and outcomes. Methods In this retrospective, single-center cohort…
View details →Zeni NG, Perricone V, Tognoli C et al. · 2026 · Poultry science
The poultry sector faces increasing sustainability challenges related to feed-food competition, volatility in the cereal markets and the environmental impact of poultry production. In this context, the use of products from the bakery and…
View details →Flämig L, Felix Zhu W, Hoffmann K et al. · 2026 · Organic & biomolecular chemistry
Agonists of the κ-opioid receptor are useful drugs for the treatment of severe pain, itching skin diseases and inflammatory and immunological diseases. Herein, novel κ agonists with the κ-pharmacophoric ethylenediamine system embedded in a…
View details →Chiang YW, Chang JY, Yeh KL et al. · 2026 · Investigative ophthalmology & visual science
Purpose To investigate whether exposure to artificial lighting with different correlated color temperatures (CCTs) affects ocular structure and myopia-related molecular signaling pathways before axial elongation in a murine model. Methods…
View details →Yamakawa R, Sakaue Y, Okada S et al. · 2026 · Gait & posture
Background Hip osteoarthritis (HOA) often leads to compensatory movements such as trunk lateral bending during gait due to pain and restricted range of motion. Because multiple joints coordinate to control the center of mass (CoM) during…
View details →Lines JB, Cungi PJ, Da Silva C et al. · 2026 · BMJ military health
Introduction Non-surgical management of non-neurological thoracic or lumbar spine (TL) fractures seems to provide good results in the civilian population, leading to return to work in most cases. However, data on the military population…
View details →García-García A, Goyoaga M, Nuño F et al. · 2026 · Carbohydrate Polymers.
Despite the increasing interest on self-healing hydrogels in the fabrication of customized scaffolds for tissue engineering applications, their optimal printability is still a challenge due to the weak mechanical stability of dynamic…
View details →Shimoyama M, Nakada-Tsukui K, Nozaki T · 2026 · Journal of cell science
Rho guanine nucleotide-exchange factors (RhoGEFs) activate Rho and Rac small GTPases, orchestrating cellular processes, such as actin remodeling, endocytosis and migration. In the protozoan parasite Entamoeba histolytica, the causative…
View details →Vera-Escalona I, Peralta-Prato J, Jorquera E et al. · 2026 · Gene
Over the decades, the Cytochrome Oxidase I (COI) gene has been widely used as a low-cost standardized identification method for phylogenetic and phylogeographic studies. However, the literature of the COI gene amplification, cloning, and…
View details →Pu Y, Gampa A, Simon C et al. · 2026 · Journal of investigative medicine : the official publication of the American Federation for Clinical Research
Atrial arrhythmias (AA), including atrial fibrillation (AF) and atrial flutter, are a significant clinical problem in oncological patients. The effect of AA on clinical outcome of patients with non-small cell lung cancer (NSCLC) is not…
View details →Kahveci ME, Yigit AA, Kabakci R · 2026 · Reproduction in domestic animals = Zuchthygiene
Linuron, chloridazon and metribuzin are herbicides thought to have potential endocrine disruption (ED) effects. This study investigated the effects of linuron, chloridazon and metribuzin on bovine granulosa cell viability and oestrogen…
View details →Kashiri M, Berk B, Yemenicioğlu A · 2026 · International journal of biological macromolecules
This study aimed at utilizing soy protein-based emulsion gel as a fat substitute in spirulina enriched plant-based spreadable cheese (PBC). For this purpose, spirulina enriched vegetable oil-in-water emulsions prepared using soy protein as…
View details →Jaafar LS, Sous NS, Shehadi HH et al. · 2026 · The Journal of nutrition
Background Emerging evidence suggests that each Branched-chain amino acids (BCAA; leucine, valine, and isoleucine) exert distinct physiological effects. Moreover, leucine and valine, but not isoleucine, are structural components of…
View details →Rebeis LM, Baruselli PS, Harden H et al. · 2026 · Journal of dairy science
The aim of this study was to evaluate the effects of administering 325 mg of recombinant bovine somatotropin (rbST) at the initiation of the synchronization protocol (SYNCd) and/or on the day of embryo transfer (ETd) using a 2 × 2…
View details →Palmi S, Arponen O, Murto M et al. · 2026 · JAMA network open
Importance Statin use has been associated with improved survival in patients with breast cancer, but there are no data on the association between statin use and survival in different intrinsic breast cancer subtypes. Objective To assess…
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