11,312 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Garrett JM, McCormick JJ, King KE et al. · 2026 · Experimental physiology
We examined whether seven consecutive days of warm-water immersion could elevate resting and exercise-induced levels of brain-derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and…
View details →Hamada R, Tamaki A, Murao M et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Purpose Bioelectrical impedance analysis (BIA) has emerged as a simple, noninvasive method for evaluating skeletal muscle. However, BIA is sensitive to fluctuations in body water and can overestimate skeletal muscle mass, which may obscure…
View details →Yavuz AY, Can F, Avci İ et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Aim Spinal meningiomas (SMs) account for approximately 25-40% of intradural extramedullary spinal tumors [1]. The classical symptomatology typically begins with pain, followed by motor and/or sensory deficits, gait disturbances, and…
View details →Molasy B, Zawolik-Kosek W, Gronowska A et al. · 2026 · Emergency radiology
Purpose To evaluate the clinical associations of admission non-contrast CT morphology in acute pancreatitis within a real-world emergency workflow. Materials and methods This retrospective observational cohort study included 264…
View details →Ahmad I, Khondker A, Rickard M et al. · 2026 · Journal of pediatric surgery
Background Testicular torsion in undescended testes (UDT) has poor salvage rates, but it remains unclear if the cryptorchid state itself confers an intrinsic disadvantage. We aimed to compare testicular salvage between UDT and descended…
View details →Moosavi D, Nejati N, Arcan C et al. · 2026 · Journal of the Academy of Nutrition and Dietetics
Background Plant-based diets have been associated with lower risks of chronic diseases; however, not all plant-based diets confer equal health benefits. Data-driven methods provide an opportunity to empirically identify distinct…
View details →Mustafa A, Wang D, Dutton C et al. · 2026 · The Journal of invasive cardiology
Objectives Transfemoral (TF) access for transcatheter aortic valve replacement (TAVR) may be challenging in patients with peripheral arterial disease (PAD). Alternative access through intra- and extrathoracic approaches can be performed.…
View details →Tasaki K, Hoshi S, Hiraoka T et al. · 2026 · Journal of clinical medicine
Background/Objectives: Lacrimal passage intubation is commonly used to treat lacrimal duct obstruction. However, conventional dacryoendoscopes, which are limited by their low resolution and comb-structure artifacts, pose challenges for…
View details →Ergün N, Karabulut SS, Türken M et al. · 2026 · Journal of fungi (Basel, Switzerland)
Candida auris is a multidrug-resistant fungal pathogen associated with high mortality in healthcare settings. Although colonization is recognized as the harbinger of invasive infection, predicting which patients will develop bloodstream…
View details →Abid H, Khan Y, Khan N et al. · 2026 · Journal of clinical medicine
Background: Angiotensin-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs) were historically considered contraindicated in severe aortic stenosis (AS) due to theoretical haemodynamic risks. Contemporary evidence…
View details →Uchida Y, Tateo S, Wakao M et al. · 2026 · European journal of haematology
Adult T-cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase…
View details →Carbonell Martínez A · 2026 · European annals of allergy and clinical immunology
Summary Background. Lipid transfer protein (LTP)-mediated food allergy represents one of the most severe and heterogeneous forms of IgE-mediated food allergy in Mediterranean populations. Although Pru p 3 is the main marker of LTP…
View details →Brothánková P, Faitlová H, Sitina M et al. · 2026 · ORL; journal for oto-rhino-laryngology and its related specialties
Aim The aim of this study was to assess the relationship between texture and the correct identification of gustatory stimuli (sweet, salty, bitter, and sour) in both healthy participants and patients with taste disorders. Patients and…
View details →Esposito G, Passeggia R, Cannata A et al. · 2026 · Healthcare (Basel, Switzerland)
Background: University counselling services provide essential support for students navigating critical academic phases. These services have proven to be successful in promoting long-term psychological well-being and student retention.…
View details →Sezgin ME, Kaya NB, Basarmak U et al. · 2026 · BMC psychology
Background AI literacy has become increasingly relevant in digitally mediated environments, yet its relationship with fear of missing out (FOMO) and nomophobia remains underexplored. Method The study used an exploratory design to examine…
View details →Kolachena V, Priyadarshi M, Singh P et al. · 2026 · Resuscitation
The optimum site of tactile stimulation (TS) during initial steps of neonatal resuscitation in the delivery room (DR) is not well-established. To compare the impact of three different sites of TS (back rub, trunk rub, and sole rub) on…
View details →Soyak B, Ozgul N · 2026 · Journal of cancer research and clinical oncology
Purpose To compare the clinicopathologic characteristics, dissemination patterns, and survival outcomes of uterine carcinosarcoma (CS) and grade 3 endometrioid adenocarcinoma (G3EAC), focusing on nodal distribution and the impact of…
View details →Gul YG, Yildiz S, Güngör H et al. · 2026 · Children (Basel, Switzerland)
Background/Objectives: Postoperative agitation (PA) and postoperative pain in pediatric patients following sevoflurane anesthesia are challenging clinical scenarios. This study aimed to evaluate the effects of intraoperative…
View details →Mori H, Masaoka T, Matsuzaki J et al. · 2026 · Digestion
Background Functional dyspepsia (FD) is a heterogeneous disorder characterized by impaired gastric accommodation and autonomic dysfunction as key pathophysiological features. Cold sensation (Hie), a commonly recognized subjective bodily…
View details →Yesilli-Puzella G, Hanbal-İbooğlu E, Karataylı Özgürsoy S · 2026 · Scientific reports
This study examined the effects of a vocal hygiene education program delivered via videoconference on voice quality and self-perceived vocal outcomes among Muslim religious officials in Turkiye. The participants were 26 imams, aged between…
View details →Massoud L, Jeng G, Parish C et al. · 2026 · Annals of plastic surgery
Adult acquired buried penis (AABP) is a condition in which the penis is obscured by excessive surrounding soft tissue or skin folds, commonly associated with obesity. It is often worsened by Balanitis Xerotica Obliterans or Lichen…
View details →Chen Z, Wang X, Zhang J et al. · 2026 · Scientific reports
This study aimed to investigate the risk factors for postoperative deep vein thrombosis (DVT) in patients with hip fractures during hospitalization to establish a foundation for early prevention and management of DVT. We conducted a…
View details →Güner A · 2026 · Healthcare (Basel, Switzerland)
Background and Objectives: Familial Mediterranean fever (FMF) is a chronic autoinflammatory disease characterized by recurrent inflammatory attacks and a persistent psychosocial burden. Although generalized anxiety symptoms have been…
View details →Vishnu Sankar KV, Maiti K, Sarkar D · 2026 · Urologia
Introduction Recurrent pelvi-ureteric junction obstruction (PUJO) poses significant management challenges, and the optimal salvage procedure remains debated. This study evaluated outcomes of various salvage interventions using a structured…
View details →Domka W, Misiołek M, Przygórzewska A et al. · 2026 · Biomedicines
Background : Glucose transporter 1 (GLUT1) is frequently upregulated in solid tumors and may reflect metabolic adaptation of malignant tissues. However, evidence regarding GLUT1 protein levels in salivary gland tumors remains limited.…
View details →Gasperoni L, Del Bono L, Farolfi A et al. · 2026 · Oncology research
Background: Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) are established maintenance treatments in ovarian cancer, but comparative efficacy across genetic profiles and relapse risk categories remains unclear. The aim of this…
View details →Kim JH, Song M, Lee K et al. · 2026 · Life (Basel, Switzerland)
Background: Gynecomastia is a benign enlargement of the male breast with multiple causes. This retrospective study evaluated whether serum estradiol (E2), testosterone (T), or the E2/T ratio differed between patients and controls, while…
View details →Derebaşınlıoğlu H, Avcı O, Çelik M et al. · 2026 · Aesthetic plastic surgery
Background Regional fascial plane blocks are widely used in breast surgery for postoperative analgesia. While analgesic benefits are established, their impact on early complications after reduction mammaplasty remains unclear. Objective To…
View details →Snyder EM, Son YJ, Li L et al. · 2026 · Physiology international
Workplace stress is one of the main sources of stress for adults, although physiological and cognitive factors may impact each person's stress response. Numerous studies have shown heart rate, heart rate variability, neural activity, and…
View details →Bouchard M, Galán-Olleros M, Ng K et al. · 2026 · European journal of pediatrics
To evaluate whether implementation of a multidisciplinary care pathway was associated with changes in unplanned emergency department (ED) visits in children with musculoskeletal infections, and to assess its impact on readmissions,…
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