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11,312 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Effects of Emergency Department Training on Buprenorphine Prescribing and Opioid Use Disorder-Associated ED Revisits: Retrospective Cohort Study.

Torchiano A, Roberts B, Haroz R et al. · 2025 · The western journal of emergency medicine

Introduction Prescribing patients buprenorphine from the emergency department (ED) is recommended by multiple organizations. However, it is unclear how best to encourage physicians to prescribe buprenorphine from the ED. Our objectives in…

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Negative / Null Result ReportMedicine

Comparison of CATCH, PECARN and CHALICE rules in children with minor head trauma.

Ferhatlar ME, Cumhur BA, Koca Y et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society

Purpose The aim of this study is to prospectively compare the diagnostic performance of the PECARN, CATCH, and CHALICE clinical decision rules in pediatric patients presenting with minor head trauma, within a rural secondary-level…

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Negative / Null Result ReportOpen accessMedicine

Computer vision for pain detection during procedural sedation.

Zarghami Y, Rad MG, Mafeld S et al. · 2026 · Scientific reports

Continual automated pain detection from facial expressions using computer vision during procedural sedation could optimize sedation dose titration and minimize pain. A prospective observational study was conducted. Participants' faces were…

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Negative / Null Result ReportMedicine

Unresponsive Systemic Mastocytosis in a Young AML With RUNX1::RUNX1T1 Fusion With Rare KIT c.1255_1257delGAC Mutation: A Clinical Deadlock.

Balraam Kv V, Nayak AR, Dass J et al. · 2026 · Journal of pediatric hematology/oncology

Background Systemic mastocytosis (SM) with associated acute myeloid leukemia (AML) is a rare malignancy usually linked to KIT p.D816V mutations. Observations We report a 17-year-old female with RUNX1::RUNX1T1-positive AML and florid mast…

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Negative / Null Result ReportMedicine

Point-of-Care Ultrasound and Clinical Findings in 14 Cats With High-Rise Syndrome.

Swanstein HKJ, Gommeren K, Langhorn R et al. · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Objective To describe point-of-care ultrasound (POCUS) and clinical findings in cats with high-rise syndrome. Design Retrospective descriptive study. Setting University hospital. Animals Fourteen cats that fell from a height. Measurements…

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Negative / Null Result ReportMedicine

Klossiella equi, an underreported parasite of equids in the Americas.

Zeldenrust EG, Carlton K, Jenkins EJ et al. · 2026 · Veterinary parasitology

Klossiella equi Baumann, 1946 (Apicomplexa: Coccidia) is a globally distributed adeleorinid parasite that infects the kidneys of equid hosts. Considered an uncommon parasite, when K. equi is detected, it is typically an incidental finding…

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Negative / Null Result ReportMedicine

Radiographic Detection of Intrathoracic Lymphadenomegaly in Dogs: How Useful Is It?

Lye G, Pollard RE, Hartman A et al. · 2026 · Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association

The intrathoracic lymph nodes (LN) of clinical interest in dogs are the sternal (STLN), cranial mediastinal (CrMLN), and tracheobronchial (TBLN) groups. Although computed tomography (CT) depicts and measures these nodes well, thoracic…

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Negative / Null Result ReportMedicine

Detection of cross-reactivity of antibodies to the N proteins of feline morbillivirus and canine distemper virus in Japanese cat plasma samples

Khin STMM, Jafar SM, Ju M et al. · 2025 · Journal of virological methods

Feline morbillivirus (FeMV) is a globally emerging virus that has been linked to chronic kidney disease (CKD) in infected cats. Immunological assays, such as enzyme-linked immunosorbent assay (ELISA), are important for studying the virus…

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Negative / Null Result ReportMedicine

Using EEG to detect lapses in sustained attention to moving stimuli.

Lowe BG, Woolgar A, Smit S et al. · 2026 · Cortex; a journal devoted to the study of the nervous system and behavior

Sustaining attention is effortful but crucial for daily life. Despite this, attentional lapses are common and can have fatal consequences (e.g., when driving). The spontaneous nature of these lapses makes studying their underlying…

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Negative / Null Result ReportOpen accessMedicine

AcrIIA8 is a putative phage structural protein of the HTJ2 family that does not inhibit Streptococcus pyogenes Cas9.

An SY, Kim I, Hong SH et al. · 2026 · Protein science : a publication of the Protein Society

Anti-CRISPR (Acr) proteins are phage-encoded anti-defense factors that suppress CRISPR-Cas immunity in bacteria. AcrIIA8 was previously identified as an inhibitor of Streptococcus pyogenes Cas9 (SpyCas9) through functional assays of…

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