11,312 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Hashemi Tayer A, Shokoohi G · 2026 · Iranian journal of microbiology
Background and objectives Umbilical cord blood-derived platelet gel (CBPG) is rich in growth factors (GFs) and antimicrobial peptides. This study evaluated its in vitro antibacterial and antifungal activity against dominant nosocomial…
View details →Landolt MA, Strebel NL, Moehrlen U et al. · 2026 · Epigenetics
Fetal repair of spina bifida aperta (fSBA) is an established intervention that improves neurological and neurodevelopmental outcomes. The present exploratory study examines whether molecular signatures related to stress regulation are…
View details →Stump K, Morar H, Talsania A et al. · 2026 · Hand (New York, N.Y.)
Background Glucagon-like peptide-1 receptor agonist (GLP-1 RA) use has demonstrated positive effects on bone metabolism and pseudoarthrosis following fusion surgery. There is, however, little evidence regarding the preoperative use of…
View details →Egeskov-Cavling AM, van Wijhe M, Yakimov V et al. · 2024 · The Journal of infectious diseases
Background Worldwide, respiratory syncytial virus (RSV) infections are among the most common causes of infant hospitalization. Host genetic factors influencing the risk and severity of RSV infection are not well known. Methods We conducted…
View details →Tan E, Williams HC · 2026 · American journal of clinical dermatology
Nicotinamide has been widely promoted as a low-cost safe chemopreventive agent against non-melanoma skin cancer. A recent large retrospective study of more than 33,000 US veterans reported a 14% reduction in overall skin cancer risk and a…
View details →Lien MC, Ruthruff E · 2023 · Journal of cognition
There is emerging evidence that suppressing distractors occur to prevent capture by those distractors. Theeuwes (2022) claimed that the absence of capture is not because of suppression but rather because a difficult, serial search causes…
View details →Mochizuki M · 2022 · Cognitive processing
The QWERTY effect is a phenomenon in which words typed with more characters from the right side (everything to the right of T, G, and B) of a standard keyboard (i.e. QWERTY keyboard) are evaluated as having a higher valence or a more…
View details →Famularo RL, Aboelata A, Schatz T et al. · 2026 · Developmental science
Human newborns are able to discriminate between certain languages but not others. This ability has long been attributed to sensitivity to rhythm-the temporal regularities in speech of different languages. Here, we demonstrate through a…
View details →Warman A, Clark A, Malcolm GL et al. · 2024 · Quarterly journal of experimental psychology (2006)
It's been repeatedly shown that pictures of graspable objects can facilitate visual processing, even in the absence of reach-to-grasp actions, an effect often attributed to the concept of affordances. A classic demonstration of this is the…
View details →Melton ZJ, Chaffin R, Kangas-Dick K et al. · 2023 · Quarterly journal of experimental psychology (2006)
The causal relationship of interpersonal liking affecting interpersonal synchrony is inconsistently documented. This study tests whether (a) interpersonal liking increases both behavioural and perceived synchrony and (b) people will…
View details →Lee MK, El Sergani AM, Herrick N et al. · 2025 · Orthodontics & craniofacial research
Objective Torus Palatinus (TP) is a common trait with an unclear aetiology. Although prior studies suggest a hereditary component, the genetic factors that influence TP risk remain unknown. The purpose of this study is to identify genetic…
View details →Tengku Kamalden TMI, Azali MZ, Chong LC et al. · 2022 · The Medical journal of Malaysia
Introduction Many factors are associated with cochlear implant (CI) outcomes and various methods of assessment for auditory and speech performance outcomes in CI are available globally. The objective of this study is to identify factors…
View details →Wengler K, Baker SC, Velikovskaya A et al. · 2024 · JAMA psychiatry
Importance The link between psychosis and dopaminergic dysfunction is established, but no generalizable biomarkers with clear potential for clinical adoption exist. Objective To replicate previous findings relating neuromelanin-sensitive…
View details →Kooij KL, Andreani NA, Keller L et al. · 2025 · The International journal of eating disorders
Objective Anorexia nervosa (AN) is a complex psychiatric disorder characterized by persistent dieting and reduced food intake, leading to significantly low body weight. Dysbiosis in the gut microbiome of patients with AN has been suggested…
View details →Kotb A, Wagdy S, Sharaf H et al. · 2025 · Scientific reports
Preeclampsia is a multi-factorial disease, with both genetic and environmental factors contributing to its development. The genetic susceptibility in preeclampsia has been determined to be around 50%. STORKHEAD_BOX1 PROTEIN 1 (STOX1), is…
View details →Long SK, Lee J, Yamani Y et al. · 2022 · Applied ergonomics
Trust is a critical factor that drives successful human-automation interaction in a myriad of modern professional environments. One seminal work on human-automation trust is Muir and Moray (1996) showing that human-machine trust evolves…
View details →Woestemeier A, Schwandt T, Lingohr P et al. · 2026 · Surgery open science
Introduction Abdominal surgery causes an inflammatory reaction in the intestines, resulting in a postoperative ileus. Mast cells can be divided into mucosal mast cells and connective tissue mast cells. In this study, we investigated mast…
View details →Jamil B, Su J, Elam K et al. · 2025 · Development and psychopathology
Introduction Past research suggests that polygenic scores for major depressive disorder (MDD-PGS), family conflict, and parental acceptance may all predict depressive outcomes among adolescents. Few studies have examined the interplay of…
View details →Burris JL, Reider LB, Oleas DS et al. · 2024 · Acta psychologica
Researchers have proposed that humans have evolved psychological mechanisms that facilitate the detection, rapid response, and subsequent avoidance of potential threats. However, some inconsistent results in the literature have called into…
View details →Chang WH, Hu TY, Kuo LK · 2026 · Diagnostics (Basel, Switzerland)
Background: Severe sepsis and septic shock remain major causes of ICU mortality despite advances in critical care. Polymyxin B hemoperfusion (PMX-HP) is widely used in Asia for refractory endotoxemia, yet the optimal session strategy…
View details →Andrashko V, Novak T, Kopecek M et al. · 2026 · Therapeutic advances in psychopharmacology
Background Ketamine is a rapid-acting antidepressant with robust evidence, but unclear predictors of therapeutic response. Objectives Based on previous knowledge, hemodynamic parameters and acute altered state of consciousness have been…
View details →Hong W, Yang Y, Xing Z · 2025 · BJPsych open
Background Depression in individuals with type 2 diabetes mellitus (T2DM) is associated with worse clinical prognosis; however, evidence regarding the relationship between depression and hypoglycaemic risk remains limited and inconclusive.…
View details →Qi J, Yin Z, Peng Y et al. · 2025 · Journal of pharmaceutical policy and practice
Background Polymyxin B is increasingly used to treat infections caused by multidrug-resistant gram-negative bacteria; however, its widespread clinical use is hindered by the high incidence of nephrotoxicity. Antioxidants, such as vitamin…
View details →Alton LA, Kutz T, Bywater CL et al. · 2024 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Metabolic cold adaptation, or Krogh's rule, is the controversial hypothesis that predicts a monotonically negative relationship between metabolic rate and environmental temperature for ectotherms living along thermal clines measured at a…
View details →Asher MW, Hecht CA, Harackiewicz JM et al. · 2025 · Motivation science
According to expectancy-value theories of motivation, individuals choose to pursue tasks that they expect to succeed at and find personally valuable. Historically, researchers have often suggested that these two factors interact to…
View details →Eshraghi N, Jayervand F, Hashemi N et al. · 2025 · BMC pregnancy and childbirth
Background To determine whether the combination of vaginal progesterone and cervical pessary initiated during the second trimester reduces the incidence of preterm birth and enhance neonatal outcomes among women diagnosed with singleton…
View details →Sulfaro AA · 2026 · Psychonomic bulletin & review
Vividness judgements are intended to capture variance in the axis that uniquely separates the experience of a mental image from other unambiguously sensory perceptual experiences, and from a completely non-sensory experience of one's…
View details →Petkova YP, Johnston JD, Collins AL · 2026 · Food science & nutrition
There is controversy regarding the differential metabolic effects of proteins from plant and animal sources. Existing literature focuses on a limited range of plant proteins consumed just before, or as part of, a mixed meal, resulting in…
View details →Ventura GC, Ryan H, Yu HN et al. · 2026 · World journal of clinical pediatrics
Children born with fetal growth restriction (FGR) or small for gestational age (SGA) face an increased risk of motor and cognitive impairments, although prevalence and severity vary across studies due to differences in definitions,…
View details →Rotondo F, Biddle K, Chen J et al. · 2022 · Neuroscience
The prospect of exploiting memory reconsolidation to treat mental health disorders has received great research interest, particularly following demonstrations that the β-adrenergic receptor antagonist propranolol, which is safe for use in…
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