11,412 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Almajed N, Al-Musharaf S, Aldhwayan MM et al. · 2025 · International journal of general medicine
Purpose Certain trace minerals, such as zinc (Zn) and magnesium (Mg), may play a role in glucose regulation and insulin signaling pathways. However, population data from the Middle East are scarce and may differ in terms of dietary and…
View details →Herzig L, Stöckert J, Lochmann M et al. · 2026 · Frontiers in sports and active living
The aim of this study was to determine if positional Worst-Case-Scenarios (WCS) during official games (OG) are replicated in Large-Sided Games (LSG) with a similar Area per Player (ApP) as OG. Twenty-one football players from the second…
View details →Bugden S, Szkudlarek E, Brannon EM · 2021 · Trends in neuroscience and education
Background Prior studies reported that practice playing an approximate arithmetic game improved symbolic math performance relative to active control groups in adults and preschool children (e.g. Park & Brannon, 2013, 2014; Park et al.,…
View details →Schriefl C, Schoergenhofer C, Buchtele N et al. · 2022 · Journal of personalized medicine
Background The clinical value of a prognostic score depends on its out-of-sample validity because inaccurate outcome prediction can be not only useless but potentially fatal. We aimed to evaluate the out-of-sample validity of a recently…
View details →Daubney ER, Flatley C, Hwang LD et al. · 2025 · Behavior genetics
Despite significant advances in pre- and postnatal care over the last century, adverse pregnancy related events still occur frequently. We used Mendelian randomisation (MR) to investigate potential causal effects of the mother's and fetal…
View details →Groncki R, Beaudry JL, Sauer JD · 2021 · Memory (Hove, England)
The way in which individuals think about their own cognitive processes plays an important role in various domains. When eyewitnesses assess their confidence in identification decisions, they could be influenced by how easily relevant…
View details →Ferhatlar ME, Cumhur BA, Koca Y et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Purpose The aim of this study is to prospectively compare the diagnostic performance of the PECARN, CATCH, and CHALICE clinical decision rules in pediatric patients presenting with minor head trauma, within a rural secondary-level…
View details →Zarghami Y, Rad MG, Mafeld S et al. · 2026 · Scientific reports
Continual automated pain detection from facial expressions using computer vision during procedural sedation could optimize sedation dose titration and minimize pain. A prospective observational study was conducted. Participants' faces were…
View details →Balraam Kv V, Nayak AR, Dass J et al. · 2026 · Journal of pediatric hematology/oncology
Background Systemic mastocytosis (SM) with associated acute myeloid leukemia (AML) is a rare malignancy usually linked to KIT p.D816V mutations. Observations We report a 17-year-old female with RUNX1::RUNX1T1-positive AML and florid mast…
View details →Slis A, Parrell B · 2026 · Journal of cognitive neuroscience
Sensory errors, mismatches between predicted sensory outcomes of movement and reafferent sensory feedback, drive changes in the feedforward control of future motor behavior that correct for those errors. Across a wide variety of motor…
View details →Kaiser A, Resasco J, Dee LE · 2026 · Nature ecology & evolution
Urban environments pose unique challenges for understanding drivers of biodiversity change, as fragmented land ownership makes traditional biodiversity monitoring and randomized experiments logistically difficult. While participatory…
View details →Swanstein HKJ, Gommeren K, Langhorn R et al. · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
Objective To describe point-of-care ultrasound (POCUS) and clinical findings in cats with high-rise syndrome. Design Retrospective descriptive study. Setting University hospital. Animals Fourteen cats that fell from a height. Measurements…
View details →Romano F, Overbey K, Durocher-Jean A et al. · 2026 · Ophthalmic surgery, lasers & imaging retina
Background and objective This study describes a novel hyperspectral imaging (HSI) approach for visualizing and measuring geographic atrophy (GA) lesions in age-related macular degeneration. Patients and methods This cross-sectional…
View details →Akinci D'Antonoli T, Adams LC, Lübberstedt J et al. · 2026 · European radiology
Objectives To evaluate whether GPT-4.1 and Llama 3.3 70B, large language models (LLMs) assessed in zero-shot, baseline configurations, detect and categorize clinically consequential errors across types that range from pattern-based to…
View details →Hasan D, Sauer J, Heller C et al. · 2026 · Clinical neuroradiology
Purpose Hemorrhagic transformation (HT) within ischemic infarcts is a critical post-stroke complication that significantly influences secondary prevention strategies, particularly the timing and safety of anticoagulation. Ultra-low field…
View details →Theingi M, Ruengdit C, Punyamung M et al. · 2026 · Laboratory medicine
Introduction This study aimed to characterize the molecular and hematologic features of hemoglobin (Hb) Hekinan II in northern Thailand and to evaluate its phenotypic expression when co-inherited with other hemoglobinopathies. Methods In…
View details →Genç S, Uzun AN, Tanriverdi̇ H · 2026 · Folia microbiologica
Carbapenem resistance in Klebsiella pneumoniae is primarily mediated by carbapenemase production. This study aimed to identify carbapenemase genes in carbapenem-resistant K. pneumoniae isolates using multiplex polymerase chain reaction…
View details →Kim H, Yu H, Kim AR et al. · 2026 · Scientific reports
Retrospective dosimetry based on thermoluminescence (TL) and optically stimulated luminescence (OSL) using personal belongings was applied to a series of small‑scale radiological accidents that occurred in South Korea between 2015 and…
View details →Lye G, Pollard RE, Hartman A et al. · 2026 · Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
The intrathoracic lymph nodes (LN) of clinical interest in dogs are the sternal (STLN), cranial mediastinal (CrMLN), and tracheobronchial (TBLN) groups. Although computed tomography (CT) depicts and measures these nodes well, thoracic…
View details →Hashimoto R, Otsuki Y, Nakamura T · 2026 · Cureus
Pulmonary metastases from papillary thyroid carcinoma (PTC) are usually detectable by computed tomography (CT) or radioactive iodine (RAI) scanning. Pathologically proven pulmonary micrometastases that are completely undetectable by…
View details →Khin STMM, Jafar SM, Ju M et al. · 2025 · Journal of virological methods
Feline morbillivirus (FeMV) is a globally emerging virus that has been linked to chronic kidney disease (CKD) in infected cats. Immunological assays, such as enzyme-linked immunosorbent assay (ELISA), are important for studying the virus…
View details →Lowe BG, Woolgar A, Smit S et al. · 2026 · Cortex; a journal devoted to the study of the nervous system and behavior
Sustaining attention is effortful but crucial for daily life. Despite this, attentional lapses are common and can have fatal consequences (e.g., when driving). The spontaneous nature of these lapses makes studying their underlying…
View details →Hayashi T, Mizobuchi K, Higa N et al. · 2026 · Ophthalmic genetics
Purpose To assess the detectability of the pathogenic RP1 Alu insertion using the PrismGuide™ inherited retinal dystrophy (IRD) panel, which targets 82 IRD genes, and whole-exome sequencing (WES). Methods A girl diagnosed with early-onset…
View details →Nichols S, Estandía A, Young CM et al. · 2026 · International journal for parasitology
Parasites are ubiquitous and exert varied ecological and evolutionary pressures on their hosts. Yet, characterising parasite diversity and distributions can be challenging and costly. Leveraging existing data to identify parasites is thus…
View details →He C, Gu X, Liu Y et al. · 2026 · Frontiers in cellular and infection microbiology
Objective This study aims to investigate the impact of mutations within the major hydrophilic region (MHR) of the hepatitis B virus (HBV) S gene on the expression, secretion, and antigenicity of hepatitis B surface antigen (HBsAg), and…
View details →Ueda M, Mitani H, Nakaki Y et al. · 2025 · Interventional radiology (Higashimatsuyama-shi (Japan)
Purpose: To evaluate the performance of automated tumor-feeder detection software in transarterial chemoembolization for hepatocellular carcinoma using angio-computed tomography. Material and Methods: This was a retrospective study of 107…
View details →Mottaghi M, Manda P, Morton EA et al. · 2025 · Cureus
We report the case of a 58-year-old woman who initially presented to the emergency department with intermittent nausea, vomiting, and left upper quadrant abdominal pain for six days. As part of the abdominal pain workup in the emergency…
View details →Ruiz-Rebollo ML, Muñoz-Moreno MF · 2025 · Medicina clinica
Background Acute pancreatitis can affect elderly people. Conflicting results have been published regarding the role of age in the course of this life-threatening disease. Aim To assess the clinical outcomes of acute pancreatitis in…
View details →Wilmshurst P · 2026 · Clinical medicine (London, England)
One-quarter of adults have a persistent (patent) foramen ovale (PFO). Right-to-left shunting through a PFO can facilitate paradoxical thromboembolism, cryptogenic stroke, paradoxical gas embolism, decompression sickness, arterial…
View details →Wei Q, Wang SA, Garcia-Manero G et al. · 2025 · Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Identification of cytogenetic abnormalities is critical for the classification and risk stratification of myelodysplastic syndromes (MDS). Optical genome mapping (OGM) is an emerging cytogenomic platform that enables high-resolution…
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