Negative / Null Result ReportOpen accessDiseases of the respiratory system
Ahmed Magdy, Khaled Shokry, Hany Foad et al. · 2017 · Egyptian Journal of Chest Disease and Tuberculosis
Objectives: This study sought to examine the pre-interventional parameters for procedural success of CTO angioplasty and to assess improvement of Left ventricular ejection fraction after successful angioplasty of CTO. Background: Chronic total occlusions (CTOs) are the most technically challenging lesion subset that interventional cardiologists might face, and that recanalization of these lesions will have the most impact on future percutaneous coronary interventions (PCI) success. Considering the recent development of catheter based technologies specific for CTO recanalization and the potenti
View details →Negative / Null Result ReportOpen accessDiseases of the respiratory system
Joshua Trivlidis, Noof Aloufi, Fatmah Al-Habeeb et al. · 2021 · Respiratory Research
Abstract Background Pulmonary fibrosis is thought to be driven by recurrent alveolar epithelial injury which leads to the differentiation of fibroblasts into α-smooth muscle actin (α-SMA)-expressing myofibroblasts and subsequent deposition of extracellular matrix (ECM). Transforming growth factor beta-1 (TGF-β1) plays a key role in fibroblast differentiation, which we have recently shown involves human antigen R (HuR). HuR is an RNA binding protein that also increases the translation of hypoxia inducible factor (HIF-1α) mRNA, a transcription factor critical for inducing a metabolic shift from
View details →Negative / Null Result ReportOpen accessDiseases of the respiratory system
Lu-lu Xu, Wen-sheng Zhao, Lang-ping Li et al. · 2022 · Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Objective: This study aimed to analyze the effects of transcutaneous electrical acupoint stimulation (TEAS) on the immune function in patients with pulmonary tuberculosis (PT) and the inflammatory response following one-lung ventilation surgery by comparing the levels of inflammatory mediators, such as tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), and interleukin 8 (IL-8); T lymphocyte subsets, including CD3+, CD4+, CD8+, and CD4+/CD8+ cells; and natural killer cells (NK cells). Methods: We randomly divided 62 patients who underwent general anesthesia for thoracotomy into two grou
View details →Negative / Null Result ReportOpen accessDiseases of the respiratory system
Rizna Abdul Cader, Kanagerajan Thoriappa, Rozita Mohd et al. · 2019 · Respiratory Medicine Case Reports
A 54 year old lady with underlying chronic lung disease on long term oxygen therapy and end stage renal disease of unknown aetiology on regular haemodialysis for two years started developing progressive shortness of breath during her routine haemodialysis. She was unable to tolerate her haemodialysis sessions which had to be terminated prematurely in view of her symptoms despite adjustment of her dry weight and treatment of anaemia. She was not in chronic fluid overload and her symptoms always worsened after initiation of haemodialysis and improved after termination of haemodialysis. She was a
View details →Negative / Null Result ReportOpen accessDiseases of the respiratory system
Suzanne L. Pollard, John J. Lima, Karina Romero et al. · 2017 · Asthma Research and Practice
Abstract Background Prior evidence suggests that vitamin D deficiency may increase the risk of asthma and atopy and impair pulmonary function in children. Methods In this cross-sectional analysis nested in a case-control study, we analyzed serum 25(OH)D concentrations in 413 children with asthma and 471 children without asthma living in two geographically adjacent study communities (Pampas and Villa El Salvador). We measured total and antigen-specific IgE levels, pulmonary function, asthma control, and exhaled nitric oxide. Results Mean 25(OH)D concentrations were 25.2 ng/mL (SD 10.1) in child
View details →Negative / Null Result ReportOpen accessDiseases of the respiratory system
Amika K. Sood, Allison J. Burbank, Michael Lawson et al. · 2019 · Respiratory Research
Abstract Background Endotoxin is a component of particulate matter linked to respiratory disease. Our group has shown that experimental endotoxin inhalation challenge reproducibly triggers neutrophilic inflammation in the airways and in peripheral blood. Sputum induction is currently the only available method for assessing airway neutrophilia but is laborious and time-consuming. This analysis examined the correlation between systemic and airway inflammatory responses to endotoxin to determine if peripheral blood could serve as a surrogate marker for neutrophilic airway inflammation. Methods We
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