Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Olga Maria Nardone, Giulio Calabrese, Alessia La Mantia et al. · 2025 · Therapeutic Advances in Gastroenterology
Background: Managing extraintestinal manifestations (EIMs) in inflammatory bowel disease (IBD) patients remains challenging due to considerable heterogeneity in diagnostic criteria and the lack of a standardised definition and validated diagnostic pathways. Delays in recognising and treating EIMs can lead to significant disease progression. Therefore, early detection and treatment are crucial. Objectives: We aimed to assess the effectiveness of a dedicated immune-mediated inflammatory diseases (IMIDs) clinic in reducing EIM diagnostic delays and improving patients’ outcomes. Design: A single-c
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Vanessa Maria Nunes Roque, Nora Manoukian Forones · 2006 · Arquivos de Gastroenterologia
RACIONAL: O câncer colorretal é a quarta causa de câncer no Brasil e o 5-fluourouracil uma das principais drogas usadas no tratamento adjuvante e paliativo dessa doença. A toxicidade da quimioterapia e as alterações de qualidade de vida, causadas pela própria doença e pelo tratamento, são motivo de muitos estudos. OBJETIVO: Avaliar nos doentes com câncer colorretal em tratamento quimioterápico, a toxicidade e possíveis alterações da qualidade de vida. MÉTODOS: Durante o período de março de 2001 a maio de 2003 no Ambulatório de Oncologia da Disciplina de Gastroenterologia Clínica da Universidad
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Suzana Müller, Carlos Fernando de Magalhães Francesconi, Ismael Maguilnik et al. · 2007 · Arquivos de Gastroenterologia
BACKGROUND: The cleansing of the colon for a colonoscopy exam must be complete so as to allow the visualization and inspection of the intestinal lumen. The ideal cleansing agent should be easily administered, have a low cost, and minimum collateral effects. Sodium picosulfate together with the magnesium citrate is a cathartic stimulant and mannitol is an osmotic laxative, both usually used for this purpose. AIMS: Assess the colon cleanliness comparing the use of mannitol and sodium picosulfate as well as evaluate the level of patient satisfaction, the presence of foam, pain, and abdominal dist
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Hao Lu, Shikuan Li, Chengzhi Wang et al. · 2025 · BMC Gastroenterology
Abstract Objective To investigate the impact of peritoneal lavage on the incidence of intra-abdominal abscess (IAA) after laparoscopic appendectomy (LA) in adults with perforated appendicitis. Methods Clinical data from adult patients intraoperatively diagnosed with perforated appendicitis and undergoing LA at the Affiliated Hospital of Qingdao University between January 2020 and January 2025 were retrospectively analyzed. Patients were divided into a no-peritoneal lavage group and a peritoneal lavage group based on whether peritoneal lavage was performed. A total of 128 patients were included
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Sumanpreet Kaur, Neha Jindal, Amandeep Kaur et al. · 2025 · BMC Gastroenterology
Abstract Background Colonoscopy is important for diagnosis, assessment and dysplasia screening in inflammatory bowel disease (IBD). A good bowel preparation is required for complete and adequate assessment. Trial design Randomised, assessor blinded parallel arm trial with 1:1 allocation. Methods Patients with IBD undergoing colonoscopy were randomised to control group (standard preparation with written instructions) or experimental group (additional brief video educational intervention). Outcome assessors and colonoscopist were masked to the allocation. Primary outcome was adequacy of bowel pr
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Lívia Beraldo de LIMA, André MALBERGIER, Priscila Dib GONÇALVES et al. · 2025 · Arquivos de Gastroenterologia
ABSTRACT Background: Hepatitis C virus (HCV) infection remains a significant public health concern. Behavioral factors such as alcohol use and psychiatric comorbidities, particularly depression, may influence disease progression and eligibility for antiviral treatment. Objective: To assess the prevalence and clinical impact of current alcohol consumption in patients with chronic HCV infection eligible for treatment with direct-acting antivirals (DAAs), and to explore its associations with depressive symptoms and clinical characteristics. Methods: This was a cross-sectional study including 109
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Pedro Boal Carvalho, Bruno Rosa, Maria João Moreira et al. · 2014 · Gastroenterology Research and Practice
Objectives. Small bowel capsule endoscopy (SBCE) plays a decisive role in the obscure gastrointestinal bleeding (OGIB) diagnosis. Antithrombotics may increase bleeding risk in patients with preexistent lesions or through direct mucosal aggression. We aimed to correlate antithrombotics usage with lesions with bleeding potential found in SBCE. Methods. Retrospective single-center study including 274 consecutive SBCE performed over 7 years for OGIB. The lesions were classified as P0 (no bleeding potential), P1 (uncertain bleeding potential: erosions), and P2 (high bleeding potential: angioectasia
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Xiaotong Xu, Jinglan Jin, Yuwei Liu et al. · 2023 · BMC Gastroenterology
Abstract Background and aims To investigate the usefulness of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), protein C (PC), and thromboelastography (TEG) to serve as a predictor of portal vein thrombosis (PVT) in patients with liver cirrhosis. Additionally, we examined the clinical significance of the above indicators in terms of disease progression. Methods A total of 123 patients with liver cirrhosis were recruited from May 2021 to December 2021, according to the imaging findings. They were divided into the PVT group (n = 52) and the non-PVT group (n = 71). Furthermore, patients
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Mohamed Abdelkhalek, Ahmed Setit, Francesco Bianco et al. · 2018 · Annals of Coloproctology
Purpose Revolutions have occurred over the last 3 decades in the management of patients with colorectal cancer. Most advances were in rectal cancer surgery, especially after the introduction of the total mesorectal excision (TME) by Heald. However, no parallel advances regarding colon cancer surgeries have occurred. In 2009, Hohenberger introduced a new concept trying to translate the survival advantages of TME to patients with colon cancer. This relatively new concept of a complete mesocolic excision (CME) with central vascular ligation (CVL) in the management of patients with colon cancer re
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Tadataka Takagi, Fumikazu Koyama, Hiroyuki Kuge et al. · 2024 · Journal of the Anus, Rectum and Colon
Objectives: This study aimed to investigate the impact of the COVID-19 pandemic on the examination and treatment of colorectal cancer (CRC) and on the behaviors of patients and practitioners. Methods: This is a retrospective analysis of the CRC patients who presented to our department between April 2019 and March 2021 and underwent surgery. Clinical presentation of CRC and time from symptom onset to medical presentation were compared between the control (April 2019 to March 2020, n=124) and COVID-19 pandemic periods (April 2020 to March 2021, n=111). Results: Two hundred and thirty-five patien
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Saixin Li, Zheng Wang, Zheng Li et al. · 2024 · BMC Gastroenterology
Abstract Background T-tube cholangiography and choledochoscopy are commonly used techniques for detecting residual bile duct stones after biliary surgery. However, the utility of routine cholangiography before T-tube removal needs further investigation. This study aims to evaluate the diagnostic efficacy of various methods for detecting residual calculi following biliary surgery. Methods We retrospectively analyzed the clinical data of 287 adult patients who underwent common bile duct exploration with T-tube drainage, followed by T-tube cholangiography and choledochoscopy, at the Department of
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Yoshiyasu Kono, Seiji Kawano, Yuki Okamoto et al. · 2018 · Therapeutic Advances in Gastroenterology
Background: The clinical outcome of patients with obscure gastrointestinal bleeding (OGIB) during antithrombotic drug therapy has not been fully investigated. Methods: Patients who underwent video capsule endoscopy (VCE) for the investigation of OGIB at Okayama University Hospital from January 2009 to March 2016 were enrolled. We evaluated the VCE findings, the patterns of OGIB, and the rate of rebleeding within 1 year in antithrombotic drug users and antithrombotic drug nonusers. Results: A total of 181 patients were enrolled. Among the antithrombotic drug users, the rate of VCE positivity in
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Naoki Akizue, Tomoaki Matsumura, Daisuke Maruoka et al. · 2018 · Endoscopy International Open
Background and study aims Endoscopic submucosal dissection (ESD) requires advanced skills to perform safely without complications. The current study evaluated the usefulness of a novel three-dimensional (3D) imaging system in ESD using porcine stomachs. Methods Four endoscopists (two trainees and two experts) performed eight ESD procedures using both 3D and 2D images. The usefulness of 3D image versus 2D image was evaluated by visibility and procedure time. In addition, occurrence of eyestrain and dizziness in 3D image was assessed. Results En bloc resection was successfully achieved, without
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
· 2014 · Gut and Liver
Background/AimsWe investigated the efficacy of prophylactic pancreatic stent placement for preventing postprocedure pancreatitis in patients undergoing endoscopic papillectomy.Methods : This retrospective study included 82 consecutive patients who underwent endoscopic papillectomy for benign ampullary neoplasm at Samsung Medical Center between August 2002 and June 2011. The patients were subdivided into two groups, namely, those who received prophylactic pancreatic stent placement and those who did not. Patient demographics, baseline blood test, tumor characteristics, and endoscopic treatment
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