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101 real negative results, null findings, and replication failures in Dentistry · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessDentistry

Tooth-Implant-Supported Prosthetic Structures Versus Implant-Supported Restorations

Marieta Bujak, Ivan Brakus, Ratka Borić · 2023 · Acta Stomatologica Croatica

Objectives: The primary aim was to compare the amount of bone height change that occurs around the tooth and the implant when having tooth-implant-supported prosthetic restorations versus bone height change that appears around implants in only implant-supported prosthetic restorations. The secondary aim was to examine the influence of various factors such as the number of teeth involved in the construction, their endodontic treatment, number of implants, the type of implantology construction, the jaw in which the construction is located, the condition of the opposite jaw, gender, age, and work

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Negative / Null Result ReportOpen accessDentistry

Effect of laser etching on shear bond strength between polyether ether ketone (PEEK) and maxillofacial silicone after accelerated ageing – an in vitro study

Ganesh RamKumar Rajapandi, Ahila Singaravel Chidambaranathan, MuthuKumar Balasubramanium · 2025 · Biomaterial Investigations in Dentistry

Introduction: Debonding of silicone prostheses from metal substructures is a frequently reported complication in prosthodontics. Polyether ether ketone (PEEK) has emerged as a promising alternative framework material owing to its favourable biomechanical properties; however, its limited bond strength to silicone remains a concern. The present study aimed to evaluate the shear bond strength between PEEK and maxillofacial silicone following laser etching of PEEK and subsequent accelerated ageing. Materials and methods: According to ISO 10477:2020, 128 PEEK specimens were fabricated using Compute

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Negative / Null Result ReportOpen accessDentistry

Comparison of the occlusal contact area of virtual models and actual models: a comparative in vitro study on Class I and Class II malocclusion models

Hyemin Lee, Jooly Cha, Youn-Sic Chun et al. · 2018 · BMC Oral Health

Abstract Backgrounds The occlusal registration of virtual models taken by intraoral scanners sometimes shows patterns which seem much different from the patients’ occlusion. Therefore, this study aims to evaluate the accuracy of virtual occlusion by comparing virtual occlusal contact area with actual occlusal contact area using a plaster model in vitro. Methods Plaster dental models, 24 sets of Class I models and 20 sets of Class II models, were divided into a Molar, Premolar, and Anterior group. The occlusal contact areas calculated by the Prescale method and the virtual occlusion by scanning

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Negative / Null Result ReportOpen accessDentistry

Antifungal Efficacy of a Permanent Silicon Soft Liner Containing Silver Nanoparticles

Sareh Habibzadeh, Solmauz Eskandarion, Seyed Mahmoud Amin Marashi et al. · 2021 · Frontiers in Dentistry

Objectives: This study aimed to evaluate the in vitro antifungal efficacy of addition of silver nanoparticles (SNPs) to Mucopren® silicone soft liner material. Materials and Methods: Twenty disc samples (8 × 2 mm) of Mucopren® silicone soft liner containing 0wt% (control), 0.5wt%, 1wt%, 2wt%, and 3wt% SNPs were fabricated. Samples were powdered and added to 150 mL of Sabouraud dextrose agar culture medium and placed on separate culture dish plates. Each plate was inoculated with 106 colony forming units per milliliter (CFUs/mL) of Candida albicans (PTCC 5027) according to the CLSI protocol, an

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Negative / Null Result ReportOpen accessDentistry

Effect of time in hardness test on artificially demineralized human dental enamel

Mirian de Waele Souchois Marsillac, Alberto Carlos Botazzo Delbem, Ricardo de Sousa Vieira · 2016 · Brazilian Journal of Oral Sciences

A cross-sectional microhardness (CSMH) test was carried out in human dental enamel exposed to a demineralizing solution in order to evaluate two different times of indentation in sound tissue and artificially induced caries. Twenty caries-free extracted human molars had one of their smooth surfaces sectioned and the enamel surface was isolated with nail polish except for an area of 6 mm2 . These specimens were submitted to artificially induced enamel caries on a lactate buffer containing 0.1 ppm fluoride (F) during 28 days. All specimens were bisected to create groups A and B in which CSMH tes

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Negative / Null Result ReportOpen accessDentistry

Demographic variations in the coping ability of people living with HIV/AIDS in Nigeria: implications for counseling

M. A. Adedigba, O. O. Ojo, E. O. Ogunbodede et al. · 2008 · Nigerian Dental Journal

Objective: To determine the coping ability of people living with HIV/AIDS (PLWHA) across demographic variations of gender, duration of living with HIV infection, marital status and living arrangements either with the family or alone. Method: The research design adopted in this study was descriptive survey. The population consisted of all PLWHA in Nigeria. The sample comprised of 117 PLWHA attending clinic regularly at General Hospital Ilesa, Osun State, Nigeria. The subjects had all been exposed to voluntary counselling and testing (VCT). Only those who consented participated in the study. A s

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Negative / Null Result ReportOpen accessDentistry

The potential of rambutan honey toothpaste in reducing the dental plaque index: a quasi Experimental study

Euis Reni Yuslianti, Anindya Sekar Ayu Ningrum, Hartanto Endrowahyudi · 2023 · Padjadjaran Journal of Dentistry

ABSTRACT Introduction: The accumulation of dental plaque is a common cause of dental and oral health problems such as caries and periodontitis, therefore it is necessary to control plaque. Brushing is the most effective way to control plaque. Currently, there are various toothpastes used by the people, one of which is herbal toothpaste. One of the herbal toothpastes that has an antibacterial potential is rambutan honey toothpaste. The purpose of this study was to analyze the effectiveness of rambutan honey toothpaste in reducing the dental plaque index. Methods: this research was Quasi Experim

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Negative / Null Result ReportOpen accessDentistry

Bacterial endotoxin adhesion to different types of orthodontic adhesives

Priscilla Coutinho ROMUALDO, Thaís Rodrigues GUERRA, Fábio Lourenço ROMANO et al. · Journal of Applied Oral Science

Abstract Bacterial endotoxin (LPS) adhesion to orthodontic brackets is a known contributing factor to inflammation of the adjacent gingival tissues. Objective The aim of this study was to assess whether LPS adheres to orthodontic adhesive systems, comparing two commercial brands. Material and Methods Forty specimens were fabricated from Transbond XT and Light Bond composite and bonding agent components (n=10/component), then contaminated by immersion in a bacterial endotoxin solution. Contaminated and non-contaminated acrylic resin samples were used as positive and negative control groups, res

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Negative / Null Result ReportOpen accessDentistry

Effects of a novel dye containing toothpaste versus regular fluoridated toothpaste for supragingival biofilm reduction in patients with chronic gingivitis: A Randomized Controlled Trial

Avita Rath, Chong Junning, Priyadarshini HR et al. · 2021 · Dentistry 3000

AIM:To compare the effects of a plaque disclosing toothpaste with a regular fluoridated toothpaste for supragingival biofilm reduction in patients with chronic gingivitis. MATERIALS AND METHODS:This study was a randomized controlled trial with a parallel design. Forty patients, both males and females aged 18-25 years with chronic generalized gingivitis (N=40) were randomly allocated to two groups of twenty each (n=20), using lottery method. Participants in the experimental group brushed with a plaque disclosing toothpaste, while participants in the control group brushed with regular fluoridate

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Negative / Null Result ReportOpen accessDentistry

Morphometric analysis of infraorbital canal using digital panoramic radiograph and proposing new classification

Chandramani B More, Palak H Shah · 2018 · Journal of Indian Academy of Oral Medicine and Radiology

Background: The infraorbital canal is one of the important anatomic structures present in the panoramic radiographic image which shows different radiographic presentations. Aim: To study the morphology of infraorbital canal on digital panoramic radiograph. Materials and Methods: The total of 1000 digital panoramic radiographs were selected from archives of the department after fulfilling the inclusion and exclusion criteria. Each radiograph was then analyzed for morphological study based on Scarfe et al. classification. The collected data were statistically analyzed by using descriptive statis

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Negative / Null Result ReportOpen accessDentistry

Dens invaginatus as a diagnostic challenge: evaluating large language models against expert endodontic reasoning

Damla Erkal, Turgut Felek, Oana-Paula Butean et al. · 2025 · BMC Oral Health

Abstract Introduction This study hypothesized that large language models (LLMs) would underperform compared to expert clinicians in diagnosing and managing complex endodontic anomalies, such as dens invaginatus, when provided with periapical radiographs. Although LLMs have shown promise in dental education and basic diagnostics, their effectiveness in nuanced clinical reasoning has remained unclear. Methods Nineteen anonymized periapical radiographs depicting challenging endodontic conditions were paired with clinical vignettes. Six advanced LLMs and one expert endodontist independently answer

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