e-ISSN: Pending
Replication FailureMedicine

Case report: false-negative Xpert MRSA/SA BC result due to spa gene deletion in a patient with methicillin-resistant Staphylococcus aureus bacteremia.

Mura T; Aso M; Kawamura K; Kanaya K; Ueda N; Iinuma Y · 2025 · Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Rapid diagnostic tests like the Xpert MRSA/SA BC assay are valuable for the early detection of Staphylococcus aureus (SA) and methicillin-resistant S. aureus (MRSA) in positive blood cultures. However, genetic variations in target regions…

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Metadata source: Europe PMC · DOI 10.1016/j.jiac.2025.102780