In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice
Troy C. Sutton; Elaine W. Lamirande; Kevin W. Bock; Ian N. Moore; Wouter Koudstaal; Muniza Rehman; Gerrit Jan Weverling; Jaap Goudsmit · 2017 · Journal of Virology
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract (excerpt)
ABSTRACT Influenza viruses of the H1N1, H2N2, and H3N2 subtypes have caused previous pandemics. H2 influenza viruses represent a pandemic threat due to continued circulation in wild birds and limited immunity in the human population. In…
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Metadata source: OpenAlex · DOI 10.1128/jvi.01603-17
