Genome-wide association study of treatment-related toxicity two years following radiotherapy for breast cancer
Harkeran K. Jandu; Colin Veal; Laura Fachal; Craig Luccarini; Miguel E. Aguado‐Barrera; Manuel Altabas; D. Azria; Adinda Baten · 2023 · Radiotherapy and Oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background and purpose Up to a quarter of breast cancer patients treated by surgery and radiotherapy experience clinically significant toxicity. If patients at high risk of adverse effects could be identified at diagnosis, their treatment could be tailored accordingly. This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity two years following whole breast radiotherapy. Materials and Methods A genome-wide association study (GWAS) was performed in 1,640 breast cancer patients with complete SNP, clinical, treatment and toxicity data, recruited a
Abstract by Harkeran K. Jandu; Colin Veal; Laura Fachal; Craig Luccarini; Miguel E. Aguado‐Barrera; Manuel Altabas; D. Azria; Adinda Baten, Radiotherapy and Oncology (2023) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1016/j.radonc.2023.109806