e-ISSN: Pending
Negative / Null Result ReportMedicine

Concentration, Antibacterial Effect, and Safety of Combining Intra-articular Epsilon-Aminocaproic Acid and Vancomycin in Primary Total Knee Arthroplasty: A Randomized Study.

Zhang Y; Wei J; Su C; Hu M; Xu H; Xiang S · 2025 · The Journal of arthroplasty

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Background In this study, we aimed to investigate the intra-articular concentration, antibacterial effect, and safety of a combination of vancomycin and epsilon-aminocaproic acid (EACA) in primary total knee arthroplasty (TKA). Methods…

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Metadata source: Europe PMC · DOI 10.1016/j.arth.2025.12.032