Results of TRIO-15, a multicenter, open-label, phase II study of the efficacy and safety of ganitumab in patients with recurrent platinum-sensitive ovarian cancer.
Davidson TM; Lebreton CL; Hendricksen AEW; Atkinson HJ; Larson MC; Oberg AL; Provencher DM; Glaspy JA · 2023 · Gynecologic oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background IGF signaling has been implicated in the pathogenesis and progression of ovarian carcinoma (OC). Single agent activity and safety of ganitumab (AMG 479), a fully human monoclonal antibody against IGF1R that blocks binding of…
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Metadata source: Europe PMC · DOI 10.1016/j.ygyno.2023.01.021