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Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology· cited by 219

Molecular evolution of genes in avian genomes

Kiwoong Nam; Carina F. Mugal; Benoît Nabholz; Holger Schielzeth; Jochen B. W. Wolf; Niclas Backström; Axel Künstner; Christopher N. Balakrishnan · 2010 · Genome biology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

BACKGROUND: Obtaining a draft genome sequence of the zebra finch (Taeniopygia guttata), the second bird genome to be sequenced, provides the necessary resource for whole-genome comparative analysis of gene sequence evolution in a non-mammalian vertebrate lineage. To analyze basic molecular evolutionary processes during avian evolution, and to contrast these with the situation in mammals, we aligned the protein-coding sequences of 8,384 1:1 orthologs of chicken, zebra finch, a lizard and three mammalian species. RESULTS: We found clear differences in the substitution rate at fourfold degenerate

Abstract by Kiwoong Nam; Carina F. Mugal; Benoît Nabholz; Holger Schielzeth; Jochen B. W. Wolf; Niclas Backström; Axel Künstner; Christopher N. Balakrishnan, Genome biology (2010) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1186/gb-2010-11-6-r68