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Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology· cited by 92

Cefiderocol-Based Combination Therapy for “Difficult-to-Treat” Gram-Negative Severe Infections: Real-Life Case Series and Future Perspectives

Davide Fiore Bavaro; Alessandra Belati; Lucia Diella; Monica Stufano; Federica Romanelli; Luca Scalone; Stefania Stolfa; Luigi Ronga · 2021 · Antibiotics

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Cefiderocol is a new cephalosporin displaying against extensively resistant (XDR) Gram-negative bacteria. We report our experience with cefiderocol-based combination therapies as “rescue” treatments in immunocompromised or critically ill patients or in patients with post-surgical infections who had failed previous regimens. A total of 13 patients were treated from 1 September 2020 to 31 March 2021. In total, 5/13 (38%) patients were classified as critically ill, due to severe COVID-19 lung failure; 4/13 (31%) patients had post-surgical infections and 4/13 (31%) had severe infections in immunoc

Abstract by Davide Fiore Bavaro; Alessandra Belati; Lucia Diella; Monica Stufano; Federica Romanelli; Luca Scalone; Stefania Stolfa; Luigi Ronga, Antibiotics (2021) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.3390/antibiotics10060652