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Failed Experiment ReportMedicine

Early antifungal prophylaxis fails to prevent influenza-associated pulmonary aspergillosis in the ICU: a target trial emulation.

Li P; Xu S; Chen C; Hu X; Li Y; Wang J; Guo L; Qiao B · 2026 · Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

WASTE classifies this as Failed Experiment Report · AI classification, approximate

An experimental approach did not work as intended — learn what to avoid before investing the same effort.

Abstract (excerpt)

Objectives To evaluate whether early antifungal prophylaxis reduces the incidence of influenza-associated pulmonary aspergillosis (IAPA) in critically ill adults with influenza. Methods We emulated a target trial using a multicentre cohort…

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Metadata source: Europe PMC · DOI 10.1016/j.cmi.2026.05.002