Genes That Escape X-Inactivation in Humans Have High Intraspecific Variability in Expression, Are Associated with Mental Impairment but Are Not Slow Evolving
Yuchao Zhang; Atahualpa Castillo-Morales; Min Jiang; Yufei Zhu; Landian Hu; Araxi O. Urrutia; Xiangyin Kong; Laurence D. Hurst · 2013 · Molecular Biology and Evolution
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
In female mammals most X-linked genes are subject to X-inactivation. However, in humans some X-linked genes escape silencing, these escapees being candidates for the phenotypic aberrations seen in polyX karyotypes. These escape genes have…
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Metadata source: OpenAlex · DOI 10.1093/molbev/mst148