Randomized, phase IIb study of low-dose cytarabine and lintuzumab versus low-dose cytarabine and placebo in older adults with untreated acute myeloid leukemia
Mikkael A. Sekeres; J. E. Lancet; Brent L. Wood; Laurie E. Grove; Larissa Sandalic; Eric L. Sievers; Joseph G. Jurcic · 2012 · Haematologica
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Improving outcomes in older adults with acute myeloid leukemia remains a formidable challenge. Lintuzumab (SGN-33; HuM195) is a humanized monoclonal antibody directed against CD33, which is expressed on the majority of myeloblasts in acute…
Excerpt shown for reference under fair use — read the full paper at the publisher.
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Metadata source: OpenAlex · DOI 10.3324/haematol.2012.066613