Geographic atrophy: pathophysiology and current therapeutic strategies
Kalpana Rajanala; Farokh Dotiwala; Arun K. Upadhyay · 2023 · Frontiers in Ophthalmology
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Abstract
Geographic atrophy (GA) is an advanced stage of age-related macular degeneration (AMD) that leads to gradual and permanent vision loss. GA is characterized by the loss of photoreceptor cells and retinal pigment epithelium (RPE), leading to distinct atrophic patches in the macula, which tends to increase with time. Patients with geographic atrophy often experience a gradual and painless loss of central vision, resulting in difficulty reading, recognizing faces, or performing activities that require detailed vision. The primary risk factor for the development of geographic atrophy is advanced ag
Abstract by Kalpana Rajanala; Farokh Dotiwala; Arun K. Upadhyay, Frontiers in Ophthalmology (2023) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fopht.2023.1327883