e-ISSN: Pending
Failed Experiment ReportMedicine

Double-Stranded DNA Sensing cGAS-STING Immune Signaling in a Rat Co-Culture Model of the Blood-Brain Barrier.

Harazin A; Reinert LS; Alam P; Hoy L; Marnow AB; Nielsen J; Lorentzen A; Otzen DE · 2026 · Cell biochemistry and function

WASTE classifies this as Failed Experiment Report · AI classification, approximate

An experimental approach did not work as intended — learn what to avoid before investing the same effort.

Abstract (excerpt)

Double-stranded DNA coming from, for example, viruses, bacteria, or apoptotic cells is recognized by the cGAS-STING signaling pathway comprising the cyclic GMP-AMP synthase (cGAS) and the stimulator of interferon genes (STING) receptors.…

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Metadata source: Europe PMC · DOI 10.1002/cbf.70240