The role of mTORC2 in the in vitro neurotoxicity of Parkinsonian mimetics 6-OHDA and MPP .
Jeremic M; Jovanovic-Tucovic M; Martinovic T; Kravic-Stevovic T; Stevanovic D; Blagojevic S; Markovic I; Trajkovic V · 2026 · Neurotoxicology
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
The mechanistic target of rapamycin complex 2 (mTORC2), a key regulator of cellular metabolism, growth, and survival, remains poorly characterized in the context of dopaminergic neurotoxicity. In this study, we investigated the role of…
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Metadata source: Europe PMC · DOI 10.1016/j.neuro.2026.103497