Investigation of Genetic Variation Underlying Central Obesity amongst South Asians
William R. Scott; Weihua Zhang; Marie Loh; Sian-Tsung Tan; Benjamin Lehne; Uzma Afzal; Juan M. Peralta; Richa Saxena · 2016 · PLoS ONE
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The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
South Asians are 1/4 of the world's population and have increased susceptibility to central obesity and related cardiometabolic disease. Knowledge of genetic variants affecting risk of central obesity is largely based on genome-wide association studies of common SNPs in Europeans. To evaluate the contribution of DNA sequence variation to the higher levels of central obesity (defined as waist hip ratio adjusted for body mass index, WHR) among South Asians compared to Europeans we carried out: i) a genome-wide association analysis of >6M genetic variants in 10,318 South Asians with focused analy
Abstract by William R. Scott; Weihua Zhang; Marie Loh; Sian-Tsung Tan; Benjamin Lehne; Uzma Afzal; Juan M. Peralta; Richa Saxena, PLoS ONE (2016) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0155478