18F-PI-2620 Tau PET is associated with cognitive and motor impairment in Lewy body disease
Joseph R. Winer; Hillary Vossler; Christina B. Young; Viktorija Smith; America Romero; Marian Shahid; Carla Abdelnour; Edward N. Wilson · 2024 · Brain Communications
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Co-pathology is frequent in Lewy body disease, which includes clinical diagnoses of both Parkinson’s disease and dementia with Lewy bodies. Measuring concomitant pathology in vivo can improve clinical and research diagnoses and prediction of cognitive trajectories. Tau PET imaging may serve a dual role in Lewy body disease by measuring cortical tau aggregation as well as assessing dopaminergic loss attributed to binding to neuromelanin within substantia nigra. We sought to characterize 18F-PI-2620, a next generation PET tracer, in individuals with Lewy body disease. We recruited 141 p
Abstract by Joseph R. Winer; Hillary Vossler; Christina B. Young; Viktorija Smith; America Romero; Marian Shahid; Carla Abdelnour; Edward N. Wilson, Brain Communications (2024) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1093/braincomms/fcae458