Enterococcus faecalis Subverts and Invades the Host Urothelium in Patients with Chronic Urinary Tract Infection
Harry Horsley; James Malone‐Lee; David Holland; Madeleine Tuz; Andrew Hibbert; Michael Kelsey; Anthony Kupelian; Jennifer Rohn · 2013 · PLoS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Bacterial urinary tract infections (UTI) are a major growing concern worldwide. Uropathogenic Escherichia coli has been shown to invade the urothelium during acute UTI in mice and humans, forming intracellular reservoirs that can evade antibiotics and the immune response, allowing recurrence at a later date. Other bacterial species, such as Staphylococcus saprophyticus, Klebsiella pneumonia and Salmonella enterica have also been shown to be invasive in acute UTI. However, the role of intracellular infection in chronic UTI causing more subtle lower urinary tract symptoms (LUTS), a particular pr
Abstract by Harry Horsley; James Malone‐Lee; David Holland; Madeleine Tuz; Andrew Hibbert; Michael Kelsey; Anthony Kupelian; Jennifer Rohn, PLoS ONE (2013) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0083637