A phase 2 trial of dasatinib in patients with locally advanced or stage IV mucosal, acral, or vulvovaginal melanoma: A trial of the ECOG‐ACRIN Cancer Research Group (E2607)
Kevin Kalinsky; Sandra Lee; Krista M. Rubin; Donald P. Lawrence; Anthony J. Iafrarte; Darell R. Borger; Kim A. Margolin; Mario M. Leitão · 2017 · Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND KIT‐directed tyrosine kinase inhibitors such as imatinib have demonstrated benefits in KIT‐mutant (KIT+) mucosal, acral, vulvovaginal, and chronically sun‐damaged (CSD) melanoma. Dasatinib has superior preclinical activity in…
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Metadata source: OpenAlex · DOI 10.1002/cncr.30663